Journal
JOURNAL OF AFFECTIVE DISORDERS
Volume 127, Issue 1-3, Pages 177-184Publisher
ELSEVIER
DOI: 10.1016/j.jad.2010.05.015
Keywords
Postpartum depression; Risk factors; Anxiety disorders; Self report measure; Structured interview
Categories
Funding
- Italian Ministry of Health
- Istituto per la ricerca e la prevenzione della Depressione E dell'Ansia (IDEA)
- Stella Major Foundations
- Pfizer Italia
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Objective: Literature underlines that the Edinburgh Postnatal Depression Scale (EPDS) is the most common measure to assess postpartum depression (PPD) worldwide and suggests that the rate of false positives is high. Furthermore, the EPDS does not distinguish between depression and anxiety. This study describes different definitions of PPD and whether pregnancy anxiety disorders are risk factors for different PPDs at both 1 month and 1 year postpartum. Method: 1066 women were recruited during pregnancy and followed until the 12th month postpartum (N = 500). Women were administered the SCID and completed the PDPI-R during pregnancy. During the postpartum women who had an EPDS score of 13 or more were administered the SCID to distinguish minor or major depressive episodes (mMD) from false positives. Results: 41.5% and 44.9% of the PPD assessed with the EPDS were false positives at theist month and during the 1st year postpartum respectively. The difference observed in prevalence rates estimated with EPDS and SCID was statistically significant both at the 1st month and during the 1st year postpartum. Overall the effect of anxiety diagnoses in predicting PPD was stronger at the 1st month than during the 1st year postpartum. The role of panic disorder is associated both with probable depression (ES = 0.82) and with mMD (ES = 0.87) at the 1st month postpartum, and predicted mMD during the 1st year postpartum (ES = 0.71). OCD predicted false positives at the 1st month postpartum (ES = 0.89). Conclusion: An antenatal screening of specific anxiety diagnoses could be extremely useful for the prevention of possible postpartum distress outcomes. (C) 2010 Elsevier B.V. All rights reserved.
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