Article
Environmental Sciences
Raffaella Lazzarini, Maria Elexpuru-Zabaleta, Francesco Piva, Matteo Giulietti, Gianluca Fulgenzi, Maria Fiorella Tartaglione, Laura Zingaretti, Adriano Tagliabracci, Matteo Valentino, Lory Santarelli, Massimo Bracci
Summary: This study analyzed the effects of exposure to extremely low-frequency electromagnetic fields (ELF-MF) on breast cancer cells. The results showed that ELF-MF increased cell viability, cellular morphology, oxidative stress response, and altered proteomic profile in breast cancer cells. Moreover, ELF-MF exposure also affected cell adhesion, migration, and invasion abilities, as well as induced changes in mitochondrial function.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Review
Oncology
Mengqian Huang, Parker Li, Feng Chen, Zehao Cai, Shoubo Yang, Xiaohong Zheng, Wenbin Li
Summary: This review summarizes the five significant underlying mechanisms and applications of ELF-PEMF in the treatment of gliomas, as well as discusses the prospects of combining ELF-PEMF with conventional therapy for treating gliomas.
Article
Biochemistry & Molecular Biology
Marina Grinberg, Maxim Mudrilov, Elizaveta Kozlova, Vladimir Sukhov, Fedor Sarafanov, Andrey Evtushenko, Nikolay Ilin, Vladimir Vodeneev, Colin Price, Evgeny Mareev
Summary: Magnetic field oscillations may affect the growth and responses of plants to environmental factors. In this study, it was found that a low-frequency magnetic field can modulate the light-induced electric reactions of wheat. Fluorescent and inhibitory analysis revealed the involvement of calcium ions and plasma membrane H+-ATPase in the development of the reaction, with the magnetic field activating H+-ATPase through increased calcium influx.
PLANT SIGNALING & BEHAVIOR
(2022)
Article
Public, Environmental & Occupational Health
Grace X. Chen, Andrea 't Mannetje, Jeroen Douwes, Leonard H. van den Berg, Neil Pearce, Hans Kromhout, Bill Glass, Naomi Brewer, Dave J. McLean
Summary: The study found that working near solar power poles in the sun can cause low-frequency electrical stimulation, premature exposure to solar electron fields may lead to premature release of toxins from plants and fresh produce. Short-term or high-intensity electrical field exposure can accelerate premature skull opening, non-solidification analog shrinking.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Review
Neurosciences
Haoyang Tian, Haozheng Zhu, Chenhao Gao, Mingxia Shi, Dekun Yang, Mingyu Jin, Fenghua Wang, Xiaohong Sui
Summary: During the past decades, the potential effects of extremely low-frequency electromagnetic fields (ELF-EMFs) on human health have gained significant attention worldwide. While there have been guidelines for magnetic field limits, further research is needed to explore the long-term effects of ELF-EMFs on organisms and systems, particularly the induced electrotherapy and potential impacts on human health under different frequencies and fields. This article systematically reviews the in vivo experimental outcomes and corresponding mechanisms to provide insights into the safety considerations of ELF-EMFs and advance the future application of electrotherapy in human health.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Environmental Sciences
Masoud Khosravipour, Masoud Ghanbari Kakavandi, Faramarz Gharagozlou, Farshad Nadri, Akbar Barzegar, Khosro Emami, Hossein Valadi Athar
Summary: A four-year repeated measures study was conducted to quantify the long-term effects of noise, extremely low-frequency electromagnetic fields (ELF-EMFs), and shift work on liver enzymes. The study found that an increase in noise and ELF-EMFs was significantly associated with changes in liver enzymes. Shift work, especially 3-rotating night shifts, also had a significant impact on liver enzymes. Furthermore, significant interaction effects were observed among noise, ELF-EMFs, and shift work.
ENVIRONMENTAL POLLUTION
(2023)
Article
Multidisciplinary Sciences
Jie Sun, Yingying Tong, Yu Jia, Xu Jia, Hua Wang, Yang Chen, Jiamin Wu, Weiyang Jin, Zheng Ma, Kai Cao, Xiangdong Li, Zhonglin Chen, Guanghua Yang
Summary: Low-frequency magnetic fields have a significant inhibitory effect on tumor growth and can be used as a therapeutic modality. The direct and indirect effects of a low-frequency magnetic field on cells were evaluated in this study. Adherent tumor cells showed higher sensitivity to magnetic field inhibition in the original environment, while the effect was suppressed in suspended cells or cells with low density. Non-tumor cell lines showed no inhibitory effect. The intracellular ion fluorescence analysis revealed changes in membrane potential, indicating hyperpolarization in adherent cells and depolarization in suspended cells.
SCIENTIFIC REPORTS
(2023)
Article
Computer Science, Information Systems
Sumou Hu, Hui Xie, Zhangming Li
Summary: This paper addresses the challenge of Sommerfeld numerical integration in the near-field region by introducing a quasi-static approximation method. It examines the propagation of electromagnetic fields using a horizontal electric dipole model and provides approximations for electromagnetic field propagation in the near region. Experimental findings highlight the presence of lateral waves as the primary mode of electromagnetic wave propagation at the seawater-air boundary.
Article
Plant Sciences
N. S. Mshenskaya, M. A. Grinberg, E. A. Kalyasova, V. A. Vodeneev, N. V. Ilin, N. N. Slyunyaev, E. A. Mareev, Y. V. Sinitsyna
Summary: Magnetic fields with a frequency of 14.3 Hz were found to have a protective effect on wheat plants under drought conditions, delaying harmful changes in transpiration and photosynthesis processes for several days.
Article
Engineering, Electrical & Electronic
Feichi Lin, Huan Zheng, Bing Xiang, Rui Xu, Wei Jiang, Liang Lang
Summary: Extremely low frequency magnetic antennas are commonly used in geophysical exploration and other applications, but vibration can lead to additional electromagnetic noise. Experimental results show that vibration-induced noise is a major source of antenna electromagnetic noise, but it can be reduced to the level of ambient electromagnetic noise with proper vibration isolation technology.
IEEE ANTENNAS AND WIRELESS PROPAGATION LETTERS
(2021)
Article
Biochemistry & Molecular Biology
Irit Markus, Evyatar Ohayon, Keren Constantini, Keren Geva-Kleinberger, Rawan Ibrahim, Angela Ruban, Yftach Gepner
Summary: Previous investigations have shown the therapeutic advantages of extremely low frequency electromagnetic fields (ELF-EMFs) in reducing inflammation and impacting biological processes. However, this study suggests that ELF-EMF has no significant overall effects on recovery rate following high-intensity exercise among athletes. Post-hoc analysis reveals modest benefits of ELF-EMF for younger athletes under certain conditions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Physics, Multidisciplinary
J. Misek, J. Jakus, K. Hamza Sladicekova, L. Zastko, M. Veternik, V. Jakusova, I. Belyaev
Summary: Cell phones expose significant parts of the human brain and head to extremely low frequency (ELF) magnetic fields (MF) classified by the IARC as a 2B carcinogen. Measurements and simulations showed that the ELF MF emitted by cell phones can reach levels comparable to those known to induce biological and health effects, including carcinogenesis. Understanding the exposure and combined effects of radiofrequency and ELF electromagnetic fields is important for future studies.
FRONTIERS IN PHYSICS
(2023)
Review
Cell Biology
Gianfranco Giorgi, Brunella Del Re
Summary: Epigenetic mechanisms regulate gene expression without altering DNA sequence, and alterations of epigenetic marks have been observed in various pathological conditions. Environmental factors may cause epigenetic changes, affecting disease risks. Exposure to ELF-MFs has been associated with epigenetic alterations such as DNA methylation, histone modifications, and microRNA expression, indicating a need for further research on the underlying molecular mechanisms.
CELL AND TISSUE RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Viacheslav V. Krylov, Galina A. Papchenkova, Irina L. Golovanova
Summary: Lednev developed a biophysical model to calculate the effective parameters of low-frequency magnetic fields targeted to calcium ions as enzyme cofactors. However, the effects of combinations of static and alternating magnetic fields with different frequencies and intensities corresponding to Lednev's model were not studied. The results of this study suggest that different combinations of magnetic fields tuned to calcium ions can affect the same molecular target, supporting Lednev's model.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Anatomy & Morphology
Nicola delli Muti, Gianmaria Salvio, Alessandro Ciarloni, Michele Perrone, Giovanni Tossetta, Raffaella Lazzarini, Massimo Bracci, Giancarlo Balercia
Summary: This study examined the effects of extremely low frequency magnetic fields (ELF-MF) on sperm parameters. The findings showed that exposure to ELF-MF at a frequency of 50 Hz (1 mT) for two hours led to significant changes in progressive motility, morphology, and the production of reactive oxygen species in human spermatozoa, suggesting that ELF-MF plays a role in altering reproductive function.
Article
Food Science & Technology
Colin D. Glen, Laura E. McVeigh, Mariel Voutounou, Yuri E. Dubrova
MOLECULAR NUTRITION & FOOD RESEARCH
(2015)
Article
Biotechnology & Applied Microbiology
Andre M. G. F. Gomes, Ruth C. Barber, Yuri E. Dubrova
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
(2015)
Article
Biotechnology & Applied Microbiology
Carole L. Yauk, Marilyn J. Aardema, Jan van Benthem, Jack B. Bishop, Kerry L. Dearfield, David M. DeMarini, Yuri E. Dubrova, Masamitsu Honma, James R. Lupski, Francesco Marchetti, Marvin L. Meistrich, Francesca Pacchierotti, Jane Stewart, Michael D. Waters, George R. Douglas
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
(2015)
Article
Multidisciplinary Sciences
Adeolu B. Adewoye, Sarah J. Lindsay, Yuri E. Dubrova, Matthew E. Hurles
NATURE COMMUNICATIONS
(2015)
Article
Biology
Elena I. Sarapultseva, Julia V. Igolkina, Viktor N. Tikhonov, Yuri E. Dubrova
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2014)
Article
Biotechnology & Applied Microbiology
Marie Voutounou, Colin D. Glen, Yuri E. Dubrova
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
(2012)
Editorial Material
Biotechnology & Applied Microbiology
Carole Lyn Yauk, J. Lucas Argueso, Scott S. Auerbach, Philip Awadalla, Sean R. Davis, David M. DeMarini, George R. Douglas, Yuri E. Dubrova, Rosalie K. Elespuru, Thomas W. Glover, Barbara F. Hales, Matthew E. Hurles, Catherine B. Klein, James R. Lupski, David K. Manchester, Francesco Marchetti, Alexandre Montpetit, John J. Mulvihill, Bernard Robaire, Wendie A. Robbins, Guy A. Rouleau, Daniel T. Shaughnessy, Christopher M. Somers, James G. Taylor, Jacquetta Trasler, Michael D. Waters, Thomas E. Wilson, Kristine L. Witt, Jack B. Bishop
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
(2013)
Article
Multidisciplinary Sciences
Michael Batie, Julianty Frost, Mark Frost, James W. Wilson, Pieta Schofield, Sonia Rocha
Article
Environmental Sciences
Elena Sarapultseva, Kseniya Ustenko, Yuri E. Dubrova
JOURNAL OF ENVIRONMENTAL RADIOACTIVITY
(2019)
Article
Biology
Leyla Djansugurova, Nazym Altynova, Oksana Cherednichenko, Elmira Khussainova, Yuri E. Dubrova
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2020)
Article
Multidisciplinary Sciences
Ayesha Singh, James W. Wilson, Christopher J. Schofield, Ruoli Chen
SCIENTIFIC REPORTS
(2020)
Review
Biochemistry & Molecular Biology
James W. Wilson, Dilem Shakir, Michael Batie, Mark Frost, Sonia Rocha
Review
Biology
Yuri E. Dubrova, Elena I. Sarapultseva
Summary: Parental exposure to radiation not only leads to mutation induction in the germline of irradiated animals but also affects their non-exposed offspring. Laboratory studies have shown compromised viability, fertility, and genome stability among the non-exposed offspring of irradiated parents. The epigenetic phenomenon of radiation-induced transgenerational effects has been established, but further research is needed to understand its manifestation in populations inhabiting radioactive-contaminated areas and the underlying mechanisms.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
C. F. M. Menck, R. S. Galhardo, A. Quinet
Summary: Studies have shown that xeroderma pigmentosum variant (XP-V) patients have mutations in the POLH gene, resulting in a high frequency of skin tumors. However, it is paradoxical that the translesion synthesis DNA polymerase eta (Pol η) in these patients can actually suppress mutations, and the mechanism behind this is still unclear. Recent evidence suggests that cyclobutane pyrimidine dimers (CPDs) play an instructional role for Pol η, enabling accurate replication of these lesions, and the mutagenic effects induced by UV radiation are caused by the deamination of C-containing CPDs. This process leads to C>T transitions, which are the most common mutations in skin cancers. The delayed replication in XP-V cells amplifies the deamination of C in CPDs and increases the burden of C>T mutations through the activity of backup TLS polymerases.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
(2024)