FTY720 (fingolimod) treatment tips the balance towards less immunogenic antigen-presenting cells in patients with multiple sclerosis

Cutting Edge: Central Nervous System Plasmacytoid Dendritic Cells Regulate the Severity of Relapsing Experimental Autoimmune Encephalomyelitis

(2014) S. L. Bailey-Bucktrout et al.   JOURNAL OF IMMUNOLOGY

Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis

(2013) Valérie Jolivel et al.   BRAIN

Cladribine exerts an immunomodulatory effect on human and murine dendritic cells

(2013) Stefan H.P. Kraus et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Circulating Monocytes Are Reduced by Sphingosine-1-Phosphate Receptor Modulators Independently of S1P3

(2013) N. D. Lewis et al.   JOURNAL OF IMMUNOLOGY

A Sphingosine-1-Phosphate Receptor 1-Directed Agonist Reduces Central Nervous System Inflammation in a Plasmacytoid Dendritic Cell-Dependent Manner

(2012) G. Galicia-Rosas et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-6-Dependent Autoimmune Disease: Dendritic Cells as a Sufficient, but Transient, Source

(2012) M. D. Leech et al.   JOURNAL OF IMMUNOLOGY

Role of C-C chemokine receptor type 7 and its ligands during neuroinflammation

(2012) Shahani Noor et al.   Journal of Neuroinflammation

Topographical and Biological Evidence Revealed FTY720-Mediated Anergy-Polarization of Mouse Bone Marrow-Derived Dendritic Cells In Vitro

(2012) Xiangfeng Zeng et al.   PLoS One

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

(2011) Kamran Ghoreschi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-1  and TGF-  Act Antagonistically in Induction and Differentially in Propagation of Human Proinflammatory Precursor CD4+ T Cells

(2011) K. Hebel et al.   JOURNAL OF IMMUNOLOGY

Estriol Generates Tolerogenic Dendritic Cells In Vivo That Protect against Autoimmunity

(2011) T. L. Papenfuss et al.   JOURNAL OF IMMUNOLOGY

A role for interleukin-2 trans-presentation in dendritic cell–mediated T cell activation in humans, as revealed by daclizumab therapy

(2011) Simone C Wuest et al.   NATURE MEDICINE

Differential effects of fingolimod (FTY720) on immune cells in the CSF and blood of patients with MS

(2011) M. C. Kowarik et al.   NEUROLOGY

CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system

(2010) Carolin Prodinger et al.   ACTA NEUROPATHOLOGICA

Fingolimod (FTY720), sphingosine 1-phosphate receptor modulator, shows superior efficacy as compared with interferon-β in mouse experimental autoimmune encephalomyelitis

(2010) Kenji Chiba et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

An Imbalance of Two Functionally and Phenotypically Different Subsets of Plasmacytoid Dendritic Cells Characterizes the Dysfunctional Immune Regulation in Multiple Sclerosis

(2010) N. Schwab et al.   JOURNAL OF IMMUNOLOGY

Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis

(2010) Jeffrey A. Cohen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Signal Transduction Inhibition of APCs Diminishes Th17 and Th1 Responses in Experimental Autoimmune Encephalomyelitis

(2009) M. Skarica et al.   JOURNAL OF IMMUNOLOGY

Inflammation Triggers Synaptic Alteration and Degeneration in Experimental Autoimmune Encephalomyelitis

(2009) D. Centonze et al.   JOURNAL OF NEUROSCIENCE