Higher levels of mucosal antibody to pneumococcal vaccine candidate proteins are associated with reduced acute otitis media caused by Streptococcus pneumoniae in young children

Contributions to Protection from Streptococcus pneumoniae Infection Using the Monovalent Recombinant Protein Vaccine Candidates PcpA, PhtD, and PlyD1 in an Infant Murine Model during Challenge

(2014) David Verhoeven et al.   Clinical and Vaccine Immunology

Review: Current and new generation pneumococcal vaccines

(2014) Charles Feldman et al.   JOURNAL OF INFECTION

Vaccination with a Streptococcus pneumoniae trivalent recombinant PcpA, PhtD and PlyD1 protein vaccine candidate protects against lethal pneumonia in an infant murine model

(2014) David Verhoeven et al.   VACCINE

Epidemiology of serotype 19A isolates from invasive pneumococcal disease in German children

(2013) Mark van der Linden et al.   BMC INFECTIOUS DISEASES

Current status and perspectives on protein-based pneumococcal vaccines

(2013) Michelle Darrieux et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid–CbpA Peptide Recombinant Fusion Protein

(2013) Beth Mann et al.   JOURNAL OF INFECTIOUS DISEASES

Vaccination against Streptococcus pneumoniae Using Truncated Derivatives of Polyhistidine Triad Protein D

(2013) Charles D. Plumptre et al.   PLoS One

New Insights into Histidine Triad Proteins: Solution Structure of a Streptococcus pneumoniae PhtD Domain and Zinc Transfer to AdcAII

(2013) Beate Bersch et al.   PLoS One

Co-colonization by Haemophilus influenzae with Streptococcus pneumoniae enhances pneumococcal-specific antibody response in young children

(2013) Qingfu Xu et al.   VACCINE

Functional maturation of nasal mucosa: role of secretory immunoglobulin A (SIgA)

(2013) Luisa Bellussi et al.   MULTIDISCIPLINARY RESPIRATORY MEDICINE

Viral and Bacterial Interactions in the Upper Respiratory Tract

(2013) Astrid A. T. M. Bosch et al.   PLoS Pathogens

Antibody in Middle Ear Fluid of Children Originates Predominantly from Sera and Nasopharyngeal Secretions

(2012) Ravinder Kaur et al.   Clinical and Vaccine Immunology

Nasopharyngeal Colonization Elicits Antibody Responses to Staphylococcal and Pneumococcal Proteins That Are Not Associated with a Reduced Risk of Subsequent Carriage

(2012) Sabine M. P. J. Prevaes et al.   INFECTION AND IMMUNITY

Biochemical, Genetic, and Serological Characterization of Two Capsule Subtypes amongStreptococcus pneumoniaeSerotype 20 Strains

(2012) Juan J. Calix et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PcpA of Streptococcus pneumoniae mediates adherence to nasopharyngeal and lung epithelial cells and elicits functional antibodies in humans

(2012) M. Nadeem Khan et al.   MICROBES AND INFECTION

Safety and immunogenicity of a pneumococcal histidine triad protein D vaccine candidate in adults

(2012) Michael Seiberling et al.   VACCINE

Safety and immunogenicity of pneumococcal protein vaccine candidates: Monovalent choline-binding protein A (PcpA) vaccine and bivalent PcpA–pneumococcal histidine triad protein D vaccine

(2012) Monica Bologa et al.   VACCINE

Safety and immunogenicity of the pneumococcal pneumolysin derivative PlyD1 in a single-antigen protein vaccine candidate in adults

(2012) Thierry Kamtchoua et al.   VACCINE

The mucosal immune system of the respiratory tract

(2012) Shintaro Sato et al.   Current Opinion in Virology

Antibody response toStreptococcus pneumoniaeproteins PhtD, LytB, PcpA, PhtE and Ply after nasopharyngeal colonization and acute otitis media in children

(2012) Michael E. Pichichero et al.   Human Vaccines & Immunotherapeutics

Next generation pneumococcal vaccines

(2011) Kristin L Moffitt et al.   CURRENT OPINION IN IMMUNOLOGY

Viral-Bacterial Interactions and Risk of Acute Otitis Media Complicating Upper Respiratory Tract Infection

(2011) Melinda M. Pettigrew et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Effectiveness of the 23-valent polysaccharide pneumococcal vaccine against invasive pneumococcal disease in people 60 years or older

(2010) Angel Vila-Corcoles et al.   BMC INFECTIOUS DISEASES

Correlation of viral load of respiratory pathogens and co-infections with disease severity in children hospitalized for lower respiratory tract infection

(2010) Anna Franz et al.   JOURNAL OF CLINICAL VIROLOGY

Serotype 19A Is the Most Common Serotype Causing Invasive Pneumococcal Infections in Children

(2010) S. L. Kaplan et al.   PEDIATRICS

Antibody response to Haemophilus influenzae outer membrane protein D, P6, and OMP26 after nasopharyngeal colonization and acute otitis media in children

(2010) Michael E. Pichichero et al.   VACCINE

Efficacy of 7-valent pneumococcal conjugate vaccination in Germany: An analysis using the indirect cohort method

(2010) Simon Rückinger et al.   VACCINE

Induction of antibodies by Staphylococcus aureus nasal colonization in young children

(2009) N.J. Verkaik et al.   CLINICAL MICROBIOLOGY AND INFECTION

Efficacy of Pneumococcal Vaccination in Children Younger Than 24 Months: A Meta-Analysis

(2009) M. Pavia et al.   PEDIATRICS

Potential role for mucosally active vaccines against pneumococcal pneumonia

(2009) Kondwani C. Jambo et al.   TRENDS IN MICROBIOLOGY

Kinetics of viral shedding and immune responses in adults following administration of cold-adapted influenza vaccine

(2009) Laura L. Hammitt et al.   VACCINE

Pneumococcal carriage and acute otitis media induce serum antibodies to pneumococcal surface proteins CbpA and PhtD in children

(2009) Birgit Simell et al.   VACCINE

Streptococcus pneumoniae Surface Protein PcpA Elicits Protection against Lung Infection and Fatal Sepsis

(2008) D. T. Glover et al.   INFECTION AND IMMUNITY