Poroelastic modeling of the intervertebral disc: A path toward integrated studies of tissue biophysics and organ degeneration

Human L3L4 intervertebral disc mean 3D shape, modes of variation, and their relationship to degeneration

(2014) John M. Peloquin et al.   JOURNAL OF BIOMECHANICS

Validation and application of an intervertebral disc finite element model utilizing independently constructed tissue-level constitutive formulations that are nonlinear, anisotropic, and time-dependent

(2014) Nathan T. Jacobs et al.   JOURNAL OF BIOMECHANICS

Numerical exploration of the combined effect of nutrient supply, tissue condition and deformation in the intervertebral disc

(2014) Andrea Malandrino et al.   JOURNAL OF BIOMECHANICS

Intervertebral disc regeneration: do nutrients lead the way?

(2014) Yong-Can Huang et al.   Nature Reviews Rheumatology

The role of endplate poromechanical properties on the nutrient availability in the intervertebral disc

(2014) A. Malandrino et al.   OSTEOARTHRITIS AND CARTILAGE

Simulation of the Progression of Intervertebral Disc Degeneration Due to Decreased Nutritional Supply

(2014) Weiyong Gu et al.   SPINE

Disc size markedly influences concentration profiles of intravenously administered solutes in the intervertebral disc: a computational study on glucosamine as a model solute

(2013) S. Motaghinasab et al.   EUROPEAN SPINE JOURNAL

Analysis of quantitative magnetic resonance imaging and biomechanical parameters on human discs with different grades of degeneration

(2013) John Antoniou et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Material property discontinuities in intervertebral disc porohyperelastic finite element models generate numerical instabilities due to volumetric strain variations

(2013) C. Ruiz et al.   Journal of the Mechanical Behavior of Biomedical Materials

Specimen specific parameter identification of ovine lumbar intervertebral discs: On the influence of fibre–matrix and fibre–fibre shear interactions

(2013) Christoph Reutlinger et al.   Journal of the Mechanical Behavior of Biomedical Materials

Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration

(2013) Nam V. Vo et al.   Spine Journal

Confined compression and torsion experiments on a pHEMA gel in various bath concentrations

(2012) Reinder W. Roos et al.   Biomechanics and Modeling in Mechanobiology

Regional annulus fibre orientations used as a tool for the calibration of lumbar intervertebral disc finite element models

(2012) Andrea Malandrino et al.   COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING

Cell viability in intervertebral disc under various nutritional and dynamic loading conditions: 3d Finite element analysis

(2012) Qiaoqiao Zhu et al.   JOURNAL OF BIOMECHANICS

Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study

(2011) G. Livshits et al.   ANNALS OF THE RHEUMATIC DISEASES

Difference in Energy Metabolism of Annulus Fibrosus and Nucleus Pulposus Cells of the Intervertebral Disc

(2011) Jessica Czamanski Salvatierra et al.   Cellular and Molecular Bioengineering

3D Finite Element Analysis of Nutrient Distributions and Cell Viability in the Intervertebral Disc: Effects of Deformation and Degeneration

(2011) Alicia R. Jackson et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Mechanical loading affects the energy metabolism of intervertebral disc cells

(2011) Hanan N. Fernando et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Interactions of environmental conditions and mechanical loads have influence on matrix turnover by nucleus pulposus cells

(2011) Cornelia Neidlinger-Wilke et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Comparison of four methods to simulate swelling in poroelastic finite element models of intervertebral discs

(2011) Fabio Galbusera et al.   Journal of the Mechanical Behavior of Biomedical Materials

Human Disc Nucleus Properties and Vertebral Endplate Permeability

(2011) Azucena G. Rodriguez et al.   SPINE

The Effect of Sustained Compression on Oxygen Metabolic Transport in the Intervertebral Disc Decreases with Degenerative Changes

(2011) Andrea Malandrino et al.   PLoS Computational Biology

Limitation of Finite Element Analysis of Poroelastic Behavior of Biological Tissues Undergoing Rapid Loading

(2010) Ian A. Stokes et al.   ANNALS OF BIOMEDICAL ENGINEERING

A biochemical/biophysical 3D FE intervertebral disc model

(2010) Y. Schroeder et al.   Biomechanics and Modeling in Mechanobiology

On the collagen criss-cross angles in the annuli fibrosi of lumbar spine finite element models

(2010) Jérôme Noailly et al.   Biomechanics and Modeling in Mechanobiology

The mechanical response of the lumbar spine to different combinations of disc degenerative changes investigated using randomized poroelastic finite element models

(2010) Fabio Galbusera et al.   EUROPEAN SPINE JOURNAL

Response analysis of the lumbar spine during regular daily activities—A finite element analysis

(2010) Hendrik Schmidt et al.   JOURNAL OF BIOMECHANICS

Analysis of cell viability in intervertebral disc: Effect of endplate permeability on cell population

(2010) A. Shirazi-Adl et al.   JOURNAL OF BIOMECHANICS

Influence of low glucose supply on the regulation of gene expression by nucleus pulposus cells and their responsiveness to mechanical loading

(2010) Christina Rinkler et al.   JOURNAL OF NEUROSURGERY-SPINE

Human intervertebral disc internal strain in compression: The effect of disc region, loading position, and degeneration

(2010) Grace D. O'Connell et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The Combined Effects of Limited Nutrition and High-Frequency Loading on Intervertebral Discs With Endplates

(2010) Svenja Illien-Jünger et al.   SPINE

Association between Annular Tears and Disk Degeneration: A Longitudinal Study

(2009) A. Sharma et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Notochordal intervertebral disc cells: Sensitivity to nutrient deprivation

(2009) Thorsten Guehring et al.   ARTHRITIS AND RHEUMATISM

Localized Intervertebral Disc Injury Leads to Organ Level Changes in Structure, Cellularity, and Biosynthesis

(2009) James C. Iatridis et al.   Cellular and Molecular Bioengineering

Statistical factorial analysis on the poroelastic material properties sensitivity of the lumbar intervertebral disc under compression, flexion and axial rotation

(2009) Andrea Malandrino et al.   JOURNAL OF BIOMECHANICS

In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression

(2009) Karin Wuertz et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Micro-structure and mechanical properties of annulus fibrous of the L4-5 and L5-S1 intervertebral discs

(2008) Dong Zhu et al.   CLINICAL BIOMECHANICS

Effects of mechanical compression on metabolism and distribution of oxygen and lactate in intervertebral disc

(2008) Chun-Yuh Huang et al.   JOURNAL OF BIOMECHANICS

Nutrient distribution and metabolism in the intervertebral disc in the unloaded state: A parametric study

(2008) Carole Magnier et al.   JOURNAL OF BIOMECHANICS

The Twin Spine Study: Contributions to a changing view of disc degeneration†

(2008) Michele C. Battié et al.   Spine Journal