Article
Orthopedics
Yue Li
Summary: This study found a positive association between body mass index (BMI) and lumbar bone mineral density (BMD), suggesting that increasing BMI may be beneficial for BMD. However, an inverted U-shaped relationship was also identified, indicating that excessive BMI may be harmful to bone health in women and blacks.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2022)
Article
Nutrition & Dietetics
Jun-Hyuk Lee, A-Ra Cho, Yu-Jin Kwon
Summary: High dairy protein intake is inversely related to the development of LMAO in Korean women, indicating that dairy protein intake may be effective in preventing incident LMAO.
CLINICAL NUTRITION
(2022)
Article
Endocrinology & Metabolism
Ho Geol Woo, Dong-Hyeok Kim, Hyungwoo Lee, Min Kyoung Kang, Tae-Jin Song
Summary: This study found that decreased skeletal muscle mass was associated with the occurrence of heart failure, while the relationship between changes in fat mass and heart failure occurrence varied, even paradoxically, depending on sex.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Multidisciplinary Sciences
Seyedeh Zahra Badrkhahan, Moein Ala, Hossein Fakhrzadeh, Arash Yaghoobi, Sara Mirzamohamadi, Seyed Masoud Arzaghi, Sina Shahabi, Farshad Sharifi, Afshin Ostovar, Noushin Fahimfar, Iraj Nabipour, Bagher Larijani, Gita Shafiee, Ramin Heshmat
Summary: This study aimed to investigate the prevalence and predictors of geriatric giants in Southern Iran. The prevalence of frailty, incontinence, immobility, depression, cognitive impairment, and malnutrition was measured among participants. The study found that geriatric giants were more common among women and older individuals.
SCIENTIFIC REPORTS
(2023)
Article
Neurosciences
Lee Smith, Jae Il Shin, Hans Oh, Christina Carmichael, Louis Jacob, Sinisa Stefanac, Rosie K. Lindsay, Pinar Soysal, Nicola Veronese, Mark A. Tully, Laurie Butler, Yvonne Barnett, Ai Koyanagi
Summary: This study examined the association between body mass index (BMI) status and mild cognitive impairment (MCI) in middle-aged and older adults in six low- and middle-income countries. The results showed that underweight, overweight, and obesity were all significantly associated with higher odds for MCI among those aged 50-64 years. However, in individuals aged >= 65 years, underweight and overweight were associated with significantly lower odds for MCI, while obesity was not significantly associated with MCI.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Cardiac & Cardiovascular Systems
Ke Zhou, Jie Xiang, Guo-yong Li, Xiao-bo Pu, Li Zhang
Summary: This study analysed the characteristics and mortality of hypertrophic cardiomyopathy (HCM) patients with different body compositions. Patients with low body mass index (BMI) and lean mass index (LMI) had higher mortality rates, while body fat (BF) was not significantly associated with mortality.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Endocrinology & Metabolism
Di Yang, Rongrong Xu, Yinfang Tu, Yunfeng Xiao, Hongwei Zhang, Weijie Liu, Pin Zhang, Haoyong Yu, Yuqian Bao, Ying Yang, Junfeng Han
Summary: Sleeve gastrectomy leads to a decrease in femoral neck and total hip bone mineral density (BMD) in both women and men. Changes in body composition are associated with BMD loss at different time points and bone sites.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Meg Lawless, Lenka H. Shriver, Laura Hubbs-Tait, Glade L. Topham, Taren Swindle, Amanda W. Harrist
Summary: This study found a significant association between weight in grade 3 and dietary restraint in grade 4 among children. However, dietary restraint in grade 3 was not associated with weight in grade 4. Child sex and race/ethnicity were not associated with BMIz or dietary restraint at any time point.
Article
Medicine, General & Internal
Parco M. Siu, Angus P. Yu, Edwin C. Chin, Doris S. Yu, Stanley S. Hui, Jean Woo, Daniel Y. Fong, Gao X. Wei, Michael R. Irwin
Summary: Tai chi is an effective approach to reduce waist circumference in adults with central obesity aged 50 years or older. The study results showed positive changes in waist circumference, body weight, and blood lipid levels in both the tai chi group and exercise group compared to the control group.
ANNALS OF INTERNAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Sahat Basana Romanti Ezer Matondang, Bennadi Adiandrian, Komang Shary Karismaputri, Cicilia Marcella, Joedo Prihartono, Dicky Levenus Tahapary
Summary: This study aims to develop formulas based on waist circumference (WC) and body mass index (BMI) to predict visceral adipose tissue (VAT) area and determine the cut-off values for central obesity in Indonesian men. The study included 32 middle-aged Indonesian men and used abdominal CT scans to measure VAT area, and anthropometric measurements to assess WC and BMI. Strong positive correlations were found between WC and VAT, as well as BMI and VAT. The formulas predicted WC of 88.5 cm and BMI of 23.9 kg/m(2) as the optimal cut-off values for central obesity in middle-aged Indonesian men.
Article
Medicine, General & Internal
Li Lin, Harry Haoxiang Wang, Ciyong Lu, Weiqing Chen, Vivian Yawei Guo
Summary: This study found that exposure to adverse childhood experiences (ACEs) was associated with higher risks of chronic diseases. There was a dose-response relationship between the number of ACEs and the risk of most chronic diseases. However, demographic and socioeconomic characteristics such as age, sex, educational level, household expenditure level, and childhood economic hardship did not significantly modify the associations between ACEs and multimorbidity.
Article
Nutrition & Dietetics
Xingqi Cao, Gan Yang, Xueqin Li, Jinjing Fu, Mayila Mohedaner, Danzengzhuoga, Terese Sara Hoj Jorgensen, George O. Agogo, Liang Wang, Xuehong Zhang, Tao Zhang, Liyuan Han, Xiang Gao, Zuyun Liu
Summary: This study aimed to estimate the influence of weight change across adulthood on biological aging acceleration in middle-aged and older adults in the United States. The findings suggest that maximal overweight, nonobese to obese, and stable obesity across adulthood, as well as an obese to nonobese pattern from middle to late adulthood, were associated with accelerated biological aging. In contrast, weight loss from young to middle adulthood was associated with decelerated biological aging.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Endocrinology & Metabolism
Chaoran Liu, Keith Yu-Kin Cheng, Xin Tong, Wing-Hoi Cheung, Simon Kwoon-Ho Chow, Sheung Wai Law, Ronald Man Yeung Wong
Summary: This study aimed to explore the relationship between obesity and sarcopenia, and the optimal proportion of fat and muscle for old individuals. The results showed that obesity was a risk factor for sarcopenia, and there was a positive correlation between muscle mass and fat mass. It was recommended that older females should have a body fat percentage between 26.0-34.6%, while older males should have a body fat percentage below 23.9% to prevent sarcopenia.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Yunsoo Soh, Chang Won Won
Summary: The study examined the relationship between body composition and frailty in community-dwelling elderly Koreans, revealing gender differences with frailty in females associated with fat-related body composition and in males with fat-free mass.
Article
Nutrition & Dietetics
Kathleen M. McClain, Christine M. Friedenreich, Charles E. Matthews, Joshua N. Sampson, David P. Check, Darren R. Brenner, Kerry S. Courneya, Rachel A. Murphy, Steven C. Moore
Summary: This study found that a thorough evaluation of fat and lean mass components provides a more accurate assessment of the associations between body composition and metabolites compared to using BMI alone. It is important to correctly characterize these relations to better understand the relationship between obesity and disease.
JOURNAL OF NUTRITION
(2022)
Review
Rheumatology
Maria Chiara Maccarone, Daniele Coraci, Gianluca Regazzo, Nicola Sarandria, Anna Scanu, Stefano Masiero
Summary: Long COVID syndrome refers to the new, returning, or persistent symptoms after the initial SARS-CoV-2 infection. Musculoskeletal symptoms have a significant impact on the quality of life in many patients. A literature review was conducted to explore the evolution of musculoskeletal symptoms in Long COVID syndrome. The findings highlight the need for interdisciplinary management and timely rehabilitative interventions.
Review
Rheumatology
Alexis Mathian, Renaud Felten, Marta E. Alarcon-Riquelme, Antony Psarras, Philippe Mertz, Francois Chasset, Edward M. Vital, Laurent Arnaud
Summary: Improved understanding of the molecular basis of innate immunity has led to the recognition of type I interferons (IFNs) as key mediators in the development of immunemediated inflammatory diseases (IMIDs). Pharmacological targeting of IFNs and their downstream signaling pathways, such as JAK1 and Tyk2, holds promise for the treatment of IMIDs.
Review
Rheumatology
Marie Robert, Marc Scherlinger
Summary: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by immune dysregulation and organ injury, involving the active role of platelets in the pathogenesis and disease progression. Platelets in SLE patients show intrinsic differences and can perpetuate inflammation by interacting with immune cells, thereby participating in organ damage and heightened cardiovascular mortality.
Review
Rheumatology
Jean Sibilia, Fabrice Berna, Jean-Gerard Bloch, Marc Scherlinger
Summary: Mind-body practices, such as mindfulness meditation, yoga, and Tai Chi, show promise in improving patient-reported outcomes in chronic rheumatic diseases, but their impact on inflammation and structural progression remains unclear.
Review
Rheumatology
Anne Tournadre, Marine Beauger
Summary: Obesity alters the characteristics of adipose tissue, leading to chronic low-grade inflammation, increased risk of chronic inflammatory diseases, and impact on treatment efficacy. Dietary and weight adjustments have a positive effect on improving inflammatory rheumatic diseases.
Article
Rheumatology
Romain Fore, Eric Liozon, Stephanie Dumonteil, Thomas Sene, Emmanuel Heron, Valentin Lacombe, Mathilde Leclercq, Julie Magnant, Clement Beuvon, Alexis Regent, Donatienne de Mornac, Maxime Samson, Perrine Smets, Jean-Francois Alexandra, Brigitte Granel, Pierre-Yves Robert, Muhammad Faiz Curumthaullee, Simon Parreau, Sylvain Palat, Holy Bezanahary, Kim Heang Ly, Anne-Laure Fauchais, Guillaume Gondran
Summary: This study aimed to evaluate whether the use of intravenous pulse of methylprednisolone reduces the risk of bilateral visual ischemia in patients with giant cell arteritis. The results showed no significant difference in the incidence of bilateral visual ischemia between the group receiving intravenous pulse of methylprednisolone and the group receiving direct prednisone.
Review
Rheumatology
Florent Eymard, Judith Aron-Wisnewsky
Summary: Obesity is a major modifiable risk factor for osteoarthritis (OA) and is associated with poorer outcomes in terms of pain, functional limitations, and response to treatments. Bariatric surgery (BS) can significantly reduce symptoms and improve function in patients with symptomatic knee OA, but its impact on long-term complications of arthroplasties appears to be disappointing. Overall, BS shows promise in reducing OA symptoms and potentially slowing disease progression.
Review
Rheumatology
Georges Marouna, Christina Fissouna, Marina Villaverde, Jean-Marc Brondelloa, Yves-Marie Pers
Summary: Recent discoveries have shown that the presence of senescent cells in osteoarticular tissues plays a crucial role in the development of osteoarthritis (OA). However, the senescence-regulatory factors associated with OA still need to be identified. Additionally, there is a lack of diagnostic and prognostic biomarkers currently used in clinics to evaluate OA patients. In the future, detecting senescence-regulatory biomarkers in patient fluids, along with imaging and clinical examination, could become a promising method for diagnosing, monitoring, assessing progression, and predicting prognosis in OA patients.
Article
Rheumatology
Patrick Yousif, Vicky Nahra, Muhammad A. Khan, Marina Magrey
Summary: Axial psoriatic arthritis (axPsA) has unique clinical and radiographic features compared to axial spondyloarthritis (axSpA). IL-23 inhibitors may be effective in treating axPsA, but further clinical trials are needed. Developing classification criteria and assessment tools for axPsA is also necessary.
Review
Rheumatology
Baptiste Gerard, Florian Bailly, Anne-Priscille Trouvin
Summary: This review aims to critically evaluate the effectiveness and safety of pharmacological treatments for chronic pain in rheumatic diseases, providing guidance for clinicians in selecting appropriate treatment options. The recommended pharmacological treatments vary depending on the specific rheumatic disease.
