Article
Immunology
Kee Thai Yeo, Chee Fu Yung, Poh Choo Khoo, Seyed Ehsan Saffari, Jane Swee Peng Sng, Mee See How, Bin Huey Quek
Summary: The study showed that palivizumab prophylaxis was effective in reducing RSV hospitalization among high-risk preterm infants of <32 weeks' gestation within the initial 6 months after discharge in a tropical setting with year-round RSV circulation.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Obstetrics & Gynecology
Emily Wener, Kimberly E. Dow, Sandra Fucile
Summary: This study aimed to assess the impact of direct breastfeeding establishment on length of hospital stay in preterm infants, finding that direct breastfeeding does not lengthen hospitalization. Apart from gestational age and days on ventilator support, other factors were not associated with duration of hospitalization.
BREASTFEEDING MEDICINE
(2021)
Article
Pediatrics
Clara Galvis, Alejandro Colmenares, Lina Cabrales, Linda Ibata, Juliana Marulanda, Oscar Ovalle, Dionisio Puello, Catherine Rojas, Martha Africano, Adriana Ballesteros, Hector Posso
Summary: This study evaluated the impact of palivizumab immunoprophylaxis on preterm infants and found that it can effectively reduce hospitalization rate and the need for intensive care unit admission due to respiratory syncytial virus infection. Patients with home oxygen, pulmonary dysplasia, and age younger than 6 months were more susceptible to respiratory infections.
PEDIATRIC PULMONOLOGY
(2022)
Review
Immunology
Diana M. Bowser, Katharine R. Rowlands, Dhwani Hariharan, Raissa M. Gervasio, Lauren Buckley, Yara Halasa-Rappel, Elizabeth L. Glaser, Christopher B. Nelson, Donald S. Shepard
Summary: This study examines the economic costs of respiratory syncytial virus (RSV) infections among infants and young children in the United States. The findings suggest that public sources bear the majority of the medical costs associated with infants' RSV treatment, and full-term infants account for the majority of RSV hospitalizations and costs.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Psychology, Clinical
Aditi Kadakia, Maryaline Catillon, Qi Fan, G. Rhys Williams, Jessica R. Marden, Annika Anderson, Noam Kirson, Carole Dembek
Summary: The estimated economic burden of schizophrenia in the US doubled between 2013 and 2019, reaching $343.2 billion in 2019. Indirect costs accounted for the majority of the burden, with caregiving, premature mortality, and unemployment being the main drivers.
JOURNAL OF CLINICAL PSYCHIATRY
(2022)
Article
Clinical Neurology
Anastasis Georgoulas, Laura Jones, Maria Pureza Laudiano-Dray, Judith Meek, Lorenzo Fabrizi, Kimberley Whitehead
Summary: In this study of 175 infants, unique regulation of sleep-wake states was observed, with particularly long durations of active sleep. Stress and nociception were found to impact sleep durations, especially in preterm infants, highlighting the importance of environmental interventions in promoting healthy sleep patterns.
Article
Biotechnology & Applied Microbiology
Elizabeth R. Packnett, Isabelle H. Winer, Heather Larkin, Abiola Oladapo, Tara Gonzalez, Matthew Wojdyla, Mitchell Goldstein, Vincent C. Smith
Summary: Respiratory syncytial virus (RSV) is a major cause of bronchiolitis and pneumonia in infants. Palivizumab is effective in reducing the risk of severe RSV disease in infants under one year. Very preterm infants have a higher risk of RSV-related hospitalization compared to term infants, but outpatient palivizumab administration can reduce the severity of these outcomes.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Article
Geriatrics & Gerontology
Chengcheng Yu, Qingyun Xia, Quanman Li, Juxiao Wu, Xiangyu Wang, Jian Wu
Summary: This study aimed to assess the hospitalization costs among patients with Chronic Obstructive Pulmonary Disease (COPD) in Henan Province, China, and investigate the factors contributing to their costs. Through a survey of 1697 COPD patients from two large tertiary hospitals, it was found that the hospitalization costs of COPD cases were substantial, with higher costs for older patients, patients with more comorbidities, and longer length of stay. Strategies should be implemented to reduce hospitalization costs for COPD patients.
Article
Geriatrics & Gerontology
Xin Dai, Mingcheng Gao, Yue Liu, Run Lv, Huanhong Chen, Huayi Miao, Ying Zhang
Summary: As China's aging population continues to grow, the prevalence of mental illness among seniors is increasing steadily. This study aims to reveal the changing trends and characteristics of economic burden among seniors with long-term hospitalization for mental illness and to analyze the influencing factors. The study found that seniors' patients with mental illness treated in specialized hospitals have higher hospitalization costs, and long-term hospitalization increases total hospitalization costs. Age has an impact on hospitalization costs for patients with organic mental disorders. Patients with affective disorders and neurotic, stress-related, and somatoform disorders covered by urban employee medical insurance also have higher hospitalization costs. Patients with severe psychiatric disorders with a 31-day readmission plan, as well as senior patients with somatoform disorders comorbid with other illnesses, incur higher hospitalization costs.
Article
Immunology
Alexander Humberg, Lisa Neuenburg, Hannah Boeckel, Mats Ingmar Fortmann, Christoph Haertel, Egbert Herting, Heilwig Hinrichs, Franziska Rademacher, Juergen Harder
Summary: This study examined the expression of antimicrobial peptides (AMPs) in the skin of preterm infants and found that the expression of AMPs was decreased in preterm infants compared to term infants. Preterm infants with infections or inflammation had higher concentrations of AMPs. These findings are significant for understanding the susceptibility to infection in preterm infants and developing new prevention strategies.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Multidisciplinary Sciences
Solomon Tessema Memirie, Amanuel Yigezu, Samuel Abera Zewdie, Alemnesh H. Mirkuzie, Sarah Bolongaita, Stephane Verguet
Summary: The hospitalization costs at Ekka Kotebe COVID-19 treatment center in Ethiopia pose a significant economic burden on the country's health system. The cost varies depending on the severity of the disease.
Article
Pediatrics
Subhash Puthuraya, Sreenivas Karnati, Hasan Othman, Rachana Sripathi, Vanishree Nandakumar, Hany Aly
Summary: This study aimed to evaluate the trends and neonatal outcomes of preterm infants born in the USA who were exposed in-utero to drugs of substance use. The results showed a trend for increased in-utero exposure to opioids and hallucinogens in preterm infants, and these infants had more neurological morbidities. This study provides important insights for research and medical practice in related fields.
PEDIATRICS AND NEONATOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Fangfei Chen, Xiaoyu Chen, Peng Gu, Xiaodong Sang, Ruijun Wu, Miaomiao Tian, Yisheng Ye, Chengxu Long, Ghose Bishwajit, Lu Ji, Da Feng, Lei Yang, Shangfeng Tang
Summary: This study investigated China's malaria hospitalization costs and explored its determinants. The study found that there is a disparity in health protection for malaria hospitalization between rural and urban areas in China, and equivocal diagnosis and comorbidity contribute to high costs.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Pediatrics
Tran H. P. Nguyen, Beverly R. Young, Amy Alabaster, David R. Vinson, Dustin G. Mark, Patrick Van Winkle, Adam L. Sharp, Judy Shan, Adina S. Rauchwerger, Tara L. Greenhow, Dustin W. Ballard
Summary: The study evaluates the performance of the American Academy of Pediatrics (AAP) Clinical Practice Guideline (CPG) in detecting invasive bacterial infections (IBI) in febrile infants without the use of C-reactive protein (CRP) and procalcitonin (PCT) tests. The AAP CPG showed high sensitivity but low specificity in identifying IBI in young infants with fevers when CRP and PCT tests were unavailable.
Article
Medicine, General & Internal
B. Kampmann, S. A. Madhi, I. Munjal, E. A. F. Simoes, B. A. Pahud, C. Llapur, J. Baker, G. Perez Marc, D. Radley, E. Shittu, J. Glanternik, H. Snaggs, J. Baber, P. Zachariah, S. L. Barnabas, M. Fausett, T. Adam, N. Perreras, M. A. Van Houten, A. Kantele, L. -M Huang, L. J. Bont, T. Otsuki, S. L. Vargas, J. Gullam, B. Tapiero, R. T. Stein, F. P. Polack, H. J. Zar, N. B. Staerke, M. Duron Padilla, P. C. Richmond, K. Koury, K. Schneider, E. V. Kalinina, D. Cooper, K. U. Jansen, A. S. Anderson, K. A. Swanson, W. C. Gruber, A. Gurtman
Summary: Vaccination of pregnant women with RSVpreF vaccine was effective in reducing severe RSV-associated lower respiratory tract illness in infants. The vaccine showed 81.8% efficacy within 90 days and 69.4% efficacy within 180 days. The vaccine was found to be safe for both mothers and infants.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
