☆ 4.4 Article

Guidelines for diagnosis and clinical classification of leishmaniasis in dogs

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION (2010)

Journal

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Volume 236, Issue 11, Pages 1184-1191

Publisher

AMER VETERINARY MEDICAL ASSOC

DOI: 10.2460/javma.236.11.1184

Keywords

-

Categories

Veterinary Sciences

Ask authors/readers for more resources

Protocol

Community support

Reagent

Community support

Authors

I am an author on this paper

Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4

Not enough ratings

Secondary Ratings

Novelty

-

Significance

-

Scientific rigor

-

Rate this paper

Recommended

Article Multidisciplinary Sciences

Preliminary study for the application of Raman spectroscopy for the identification of Leishmania infected dogs

Acri Giuseppe, Falcone Annastella, Claudia Giannetto, Giudice Elisabetta, Piccione Giuseppe, Testagrossa Barbara, Luca Cicero, Giovanni Cassata, Di Pietro Simona

Summary: Raman spectroscopy is a rapid qualitative and quantitative technique that can be used to determine multiple components in biological fluids. This study used Raman spectroscopy to differentiate between Leishmaniasis-infected dogs and healthy dogs. Further research is needed to confirm the feasibility of Raman spectroscopy as a diagnostic tool for Leishmaniasis.

SCIENTIFIC REPORTS (2022)

Add to Collection

Article Microbiology

Comparative Study of Real-Time PCR (TaqMan Probe and Sybr Green), Serological Techniques (ELISA, IFA and DAT) and Clinical Signs Evaluation, for the Diagnosis of Canine Leishmaniasis in Experimentally Infected Dogs

Maria Paz Peris, Adriana Esteban-Gil, Paula Ortega-Hernandez, Mariano Morales, Nabil Halaihel, Juan Antonio Castillo

Summary: The study used Sybr Green and TaqMan Probe based real-time PCRs to detect Leishmania sp. in dogs, finding that conjunctival swab could be the optimal sample for parasite detection in both early and late stages, avoiding the need for other sample collection.

MICROORGANISMS (2021)

Add to Collection

Article Gastroenterology & Hepatology

Toward an evidence-based approach for cholangitis diagnosis

James Buxbaum, Bashar Qumseya, Sachin Wani

Summary: Despite the lack of consensus criteria for the diagnosis of cholangitis, the BILE criteria appears to be a promising approach in identifying high-risk patients. Further validation studies are needed to confirm its diagnostic performance and ability to prevent unnecessary ERCP.

GASTROINTESTINAL ENDOSCOPY (2021)

Add to Collection

Article Biology

Toward automating the diagnosis of gastrointestinal parasites in cats and dogs

L. M. Joao, Leticia Rodrigues Proenca, Saulo Hudson Nery Loiola, Sandra Valeria Inacio, Bianca Martins dos Santos, Stefany Laryssa Rosa, Felipe Augusto Soares, Vitoria Castilho Stefano, Daniel Osaku, Celso Tetsuo Nagase Suzuki, Katia Denise Saraiva Bresciani, Jancarlo Ferreira Gomes, Alexandre Xavier Falcao

Summary: Diagnosing gastrointestinal parasites through microscope slide examination can lead to human interpretation errors. We have developed an automated process to overcome these errors, including a new processing technique called TF-Test VetPet and a deep learning-based microscopy image analysis pipeline. TF-Test VetPet improves image quality, resulting in automated analysis that can accurately identify parasites in cats and dogs with an average accuracy of 98.6%. We have also provided datasets of parasite images obtained using TF-Test VetPet.

COMPUTERS IN BIOLOGY AND MEDICINE (2023)

Add to Collection

Article Parasitology

Frequency of detection and load of amastigotes in the pancreas of Leishmania infantum-seropositive dogs: clinical signs and histological changes

William de Oliveira Kost, Sandro Antonio Pereira, Fabiano Borges Figueiredo, Artur Augusto Velho Mendes Junior, Maria de Fatima Madeira, Luciana de Freitas Campos Miranda, Raquel de Vasconcellos Carvalhaes de Oliveira, Luiz Claudio Ferreira, Fernanda Nazare Morgado, Rodrigo Caldas Menezes

Summary: This study found that L. infantum is one of the etiological agents of chronic pancreatitis in dogs, but the frequency of detection and parasite load are low in the pancreas. Poor body condition and cachexia are associated with pancreatitis as well as with spleen and/or bone marrow infection.

PARASITES & VECTORS (2021)

Add to Collection

Article Infectious Diseases

Clinical and laboratory characteristics of hemophagocytic lymphohistiocytosis induced by Leishmania infantum infection

Qi Shi, Minjun Huang, Xiaoli Li, Xiaoyan Zheng, Fei Wang, Yang Zou, Lei Wang, Jidong Jia

Summary: The study found significant differences in clinical and laboratory characteristics between patients with VL associated HLH and those with VL only, including higher inflammation status, higher parasite load, and higher risk of complications in VL associated HLH patients.

PLOS NEGLECTED TROPICAL DISEASES (2021)

Add to Collection

Review Parasitology

Phenotypical and genotypical differences among Leishmania (Leishmania) amazonensis isolates that caused different clinical frames in humans and dogs: A systematic review

Taylon Felipe Silva, Fernanda Tomiotto-Pellissier, Aline Kuhn Sbruzzi Pasquali, Fernanda Pinto-Ferreira, Wander Rogerio Pavanelli, Ivete Conchon-Costa, Italmar Teodorico Navarro, Eloiza Teles Caldart

Summary: The study revealed that the exact mechanism leading to different clinical manifestations among strains of the same species is still uncertain, and future studies are needed to better elucidate this phenomenon.

ACTA TROPICA (2021)

Add to Collection

Article Multidisciplinary Sciences

Chromosome-scale genome sequencing, assembly and annotation of six genomes from subfamily Leishmaniinae

Hatim Almutairi, Michael D. Urbaniak, Michelle D. Bates, Narissara Jariyapan, Godwin Kwakye-Nuako, Vanete Thomaz Soccol, Waleed S. Al-Salem, Rod J. Dillon, Paul A. Bates, Derek Gatherer

Summary: The study provides raw and processed data from genome sequencing of isolates from six species of parasites. The data has been deposited in various databases and repositories, serving as a resource for comparative genomics and applications in parasitology.

SCIENTIFIC DATA (2021)

Add to Collection

Review Pharmacology & Pharmacy

Dogs as a Model for Chemotherapy of Chagas Disease and Leishmaniasis

Marta de Lana, Rodolfo Cordeiro Giunchetti

Summary: The study on dog models with Chagas disease and leishmaniasis chemotherapy showed that combination chemotherapy was more effective than monotherapy. Treatment demonstrated benefits in reducing or eliminating lesions and controlling parasitism.

CURRENT PHARMACEUTICAL DESIGN (2021)

Add to Collection

Review Infectious Diseases

Clinical criteria for Mucosal Leishmaniasis diagnosis in rural South America: A systematic literature review

Jacob M. Bezemer, Kevin Meesters, Cristhian L. Naveda, Paulo R. L. Machado, Manuel Calvopina, Mariska M. G. Leeflang, Henk D. F. H. Schallig, Henry J. C. de Vries

Summary: Mucosal Leishmaniasis is a disease caused by Leishmania parasites that severely affects the quality of life of under-resourced populations in South America. The low sensitivity of microscopy results and the unavailability of accurate diagnostic tests hinder the diagnosis, making it necessary to find effective clinical criteria.

PLOS NEGLECTED TROPICAL DISEASES (2022)

Add to Collection

Review Parasitology

Correlations between tissue parasite load and common clinical signs in dogs naturally infected by Leishmania infantum

Ursula Maira Russo Chagas, Daniel Moreira de Avelar, Andreza Pain Marcelino, Gustavo Fontes Paz, Celia Maria Ferreira Gontijo

Summary: qPCR was used to quantify parasite load in dogs infected with Leishmania infantum, showing skin as the tissue with the highest parasite load and a strong correlation between clinical manifestations and parasite load.

VETERINARY PARASITOLOGY (2021)

Add to Collection

Article Infectious Diseases

Immunogenic mapping of rDyn-1 and rKDDR-plus proteins and selection of oligopeptides by immunoblotting for the diagnosis of Leishmania infantum-infected dogs

Williane Fernanda Siqueira, Mariana Santos Cardoso, Vanessa Gomes Fraga, Jennifer Ottino, Vitor Marcio Ribeiro, Carolina Novato Gondim, Joziana Muniz de Paiva Barcante, Ana Carolina Amado Gomes, Alexsandro Sobreira Galdino, Kasper Eersels, Bart van Grinsven, Daniella Castanheira Bartholomeu, Lilian Lacerda Bueno, Thomas Cleij, Ricardo Toshio Fujiwara

Summary: This study aimed to compare the efficacy of two previously described whole proteins with their more immunoreactive synthetic peptides in the diagnosis of Canine leishmaniasis (CanL). The results showed that ELISA using the mixture of peptides and the rDyn-1 protein showed high performance in the diagnosis of CanL.

PLOS NEGLECTED TROPICAL DISEASES (2023)

Add to Collection

Article Multidisciplinary Sciences

Risk prediction of clinical adverse outcomes with machine learning in a cohort of critically ill patients with atrial fibrillation

Lorenzo Falsetti, Matteo Rucco, Marco Proietti, Giovanna Viticchi, Vincenzo Zaccone, Mattia Scarponi, Laura Giovenali, Gianluca Moroncini, Cinzia Nitti, Aldo Salvi

Summary: The study utilized topological data analysis and machine learning techniques to identify risk factors for therapeutic failure, stroke/TIA, and major bleeding in critically ill patients with pre-existing atrial fibrillation. Specific risk factors were identified and dedicated clinical prediction models were successfully engineered, accurately predicting clinical outcomes for these patients.

SCIENTIFIC REPORTS (2021)

Add to Collection

Article Multidisciplinary Sciences

Targeted deep learning classification and feature extraction for clinical diagnosis

Yiting Tsai, Vikash Nanthakumar, Saeed Mohammadi, Susan A. Baldwin, Bhushan Gopaluni, Fei Geng

Summary: This paper proposes a feature extractor that uses a deep learning model to discover protein biomarkers for various classification problems. The study found that compared to traditional models, using this method can improve class separation and reduce false discovery rates.

ISCIENCE (2023)

Add to Collection

Article Multidisciplinary Sciences

Clinical decision support tool for diagnosis of COVID-19 in hospitals

Claude Saegerman, Allison Gilbert, Anne-Francoise Donneau, Marjorie Gangolf, Anh Nguvet Diep, Cecile Meex, Sebastien Bontems, Marie-Pierre Hayette, Vincent D'Orio, Alexandre Ghuysen

Summary: This study investigated clinical patterns of suspected COVID-19 patients and identified fever and dry cough, along with patient age, as the main predictors using multivariate binary logistic regression. An overall pondered score (OPS) was calculated to discriminate between confirmed and unconfirmed COVID-19 patients, showing a significant negative correlation with qRT-PCR cycle threshold values.

PLOS ONE (2021)

Add to Collection

Article Veterinary Sciences

Utility and prognostic significance of leukocyte ratios in dogs with Primary Immune-Mediated Hemolytic Anemia

Chiara Alaimo, Giulia De Feo, George Lubas, Alessandra Gavazza

Summary: Based on a retrospective study of medical records from two veterinary teaching hospitals, this study suggests that lower monocyte to lymphocyte ratio (MLR) and higher neutrophil to monocyte ratio (NMR) may predict poorer prognosis in untreated dogs with immune-mediated hemolytic anemia (IMHA).

VETERINARY RESEARCH COMMUNICATIONS (2023)

Add to Collection

Editorial Material Parasitology

ALIVE: The 1st Animal Leishmaniosis International Veterinary Event in a hybrid format

Guadalupe Miro, Juliana Sarquis, Luis Cardoso, Patrick Bourdeau, Laia Solano-Gallego, Gaetano Oliva, Maria Grazia Pennisi, Christine Petersen, Lluis Ferrer, Gad Baneth

Summary: The organizers of the 1st congress on animal leishmaniosis (ALIVE) in Malaga, Spain, discuss the recent advances in the field presented during the meeting.

TRENDS IN PARASITOLOGY (2022)

Add to Collection

Article Veterinary Sciences

The Leishmaniasis

Gad Baneth, Laia Solano-Gallego

VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE (2022)

Add to Collection

Review Parasitology

Vector-borne and other pathogens of potential relevance disseminated by relocated cats

Ricardo Guillermo Maggi, Vicky Halls, Friederike Kramer, Michael Lappin, Maria Grazia Pennisi, Andrew S. Peregrine, Xavier Roura, Bettina Schunack, Valeria Scorza, Severine Tasker, Gad Baneth, Patrick Bourdeau, Dwight D. Bowman, Edward B. Breitschwerdt, Gioia Capelli, Luis Cardoso, Filipe Dantas-Torres, Gerhard Dobler, Lluis Ferrer, Luigi Gradoni, Peter Irwin, Frans Jongejan, Volkhard A. J. Kempf, Barbara Kohn, Susan Little, Maxime Madder, Carla Maia, Mary Marcondes, Guadalupe Miro, Torsten Naucke, Gaetano Oliva, Domenico Otranto, Barend L. Penzhorn, Martin Pfeffer, Angel Sainz, SungShik Shin, Laia Solano-Gallego, Reinhard K. Straubinger, Rebecca Traub, Ian Wright

Summary: Large populations of unowned cats pose various issues worldwide, including animal welfare, ecology, society, and public health. Relocating and homing these cats is seen as a means to alleviate suffering and social problems, while also contributing to ethical population control. Understanding individual cats' lifestyle and disease status is crucial for veterinary professionals and those working with cat charities to minimize cat stress and the spread of pathogens, especially vector-borne ones.

PARASITES & VECTORS (2022)

Add to Collection

Article Veterinary Sciences

Comparison of six microscopic methods and two operators for estimation of white and red blood cells in canine urine sediment

Marco Giraldi, Filippo Tagliasacchi, Saverio Paltrinieri, Tiziana Vitiello, Paola Rossetti, Paola Scarpa

Summary: This study aimed to compare the results obtained by two operators using six microscopic methods for the quantification of urinary leukocytes and erythrocytes. The results showed that although there were some differences between operators, all methods exhibited good reproducibility. Stained sediment evaluations allowed better identification of leukocytes by inexperienced operators but introduced bias in erythrocyte counts.

VETERINARY CLINICAL PATHOLOGY (2023)

Add to Collection

Article Agriculture, Dairy & Animal Science

Gene Expression Profiles of the Immuno-Transcriptome in Equine Asthma

Elisa Padoan, Serena Ferraresso, Sara Pegolo, Carlo Barnini, Massimo Castagnaro, Luca Bargelloni

Summary: This study comprehensively defined the transcriptomic fingerprints of mild and severe equine asthma using gene expression analysis. The pathogenesis of equine asthma involves reduced mucociliary clearance and excessive complement activation leading to tissue injury. Furthermore, severe equine asthma is characterized by chronic inflammation and tissue remodeling similar to human asthma.

ANIMALS (2023)

Add to Collection

Article Veterinary Sciences

Clinicopathological findings and risk factors associated with Cytauxzoon spp. infection in cats: A case-control study (2008-2021)

Erika Carli, Laia Solano-Gallego, Stefano De Arcangeli, Laura Ventura, Elisa Ligorio, Tommaso Furlanello

Summary: This study evaluated clinicopathological findings and risk factors associated with Cytauxzoon spp. infection in domestic cats. The results showed that infection mainly manifested as subclinical infection, and anemia was more common in subclinical infected cats.

FRONTIERS IN VETERINARY SCIENCE (2022)

Add to Collection

Article Veterinary Sciences

Pre-analytical and analytical variability of reticulocyte counts in dogs

Roberta Franchi, Marco Giraldi, Walter Bertazzolo, Francesca Bartolini, Francesca Maria Di Maria, Saverio Paltrinieri

Summary: This study aimed to evaluate potential sources of analytical and pre-analytical errors when performing automated and manual counts. The results showed that intra-assay coefficients of variation were lower for automated counts than for manual counts. Comparison between automated and mean total manual reticulocyte count showed no significant differences. In both refrigerated samples and those stored at room temperature, an increase in reticulocyte count was recorded only after 72 hours. It is recommended to perform the analysis as soon as possible after sampling.

VETERINARY RECORD (2023)

Add to Collection

Article Agriculture, Dairy & Animal Science

Signalment, Immunological and Parasitological Status and Clinicopathological Findings of Leishmania-Seropositive Apparently Healthy Dogs

Marta Baxarias, Oriol Jornet-Rius, Giulia Donato, Cristina Mateu, Ma Magdalena Alcover, Maria Grazia Pennisi, Laia Solano-Gallego

Summary: This study highlights the importance of evaluating the clinical health status of apparently healthy L. infantum-seropositive dogs in Europe. Routine laboratory tests, including antibody quantification and PCR, should be performed to detect sick dogs with clinicopathological findings that would otherwise remain undetected.

ANIMALS (2023)

Add to Collection

Article Microbiology

Effect of Local Administration of Meglumine Antimoniate and Polyhexamethylene Biguanide Alone or in Combination with a Toll-like Receptor 4 Agonist for the Treatment of Papular Dermatitis due to Leishmania infantum in Dogs

Iciar Martinez-Florez, Maria Jose Guerrero, Annabel Dalmau, Maria Cabre, Maria Magdalena Alcover, Diana Berenguer, Liam Good, Roser Fisa, Cristina Riera, Laura Ordeix, Laia Solano-Gallego

Summary: This study evaluated the safety and clinical efficacy of local meglumine antimoniate, locally administered polyhexamethylene biguanide (PHMB) alone or PHMB in combination with a Toll-like receptor 4 agonist (TLR4a) for the treatment of papular dermatitis due to L. infantum infection. The results showed that local administration of meglumine antimoniate had the fastest clinical resolution, while local administration of PHMB (alone or with TLR4a) also showed positive results. In conclusion, the local administration of meglumine antimoniate appears to be safe and clinically efficient for the treatment of canine papular dermatitis due to L. infantum infection.

PATHOGENS (2023)

Add to Collection

Article Veterinary Sciences

Effect of storage on the nitro blue tetrazolium reduction test in dog blood samples

Marta Baxarias, Laia Solano-Gallego

Summary: This study evaluated the effect of storage on NBTT in dog blood samples. The results showed that the NBTT can be performed up to 72 h after the collection of canine blood if correctly refrigerated at 4℃.

VETERINARY CLINICAL PATHOLOGY (2023)

Add to Collection

Article Virology

Chitinase-1 Activity in Serum of Cats with FIP

Angelica Stranieri, Gabriela Avila Morales, Laura Brusasco, Saverio Paltrinieri

Summary: This study aimed to investigate the possible changes in serum chitotriosidase (CHIT1) activity in cats with feline infectious peritonitis (FIP). The results showed that CHIT1 activity can identify sick cats and, to some extent, cats with FIP, although further studies are needed to fully explore its diagnostic or prognostic potential for FIP.

VIRUSES-BASEL (2023)

Add to Collection

Article Veterinary Sciences

Serological survey of Leishmania infantum in apparently healthy dogs in different areas of Spain

Marta Baxarias, Cristina Mateu, Guadalupe Miro, Laia Solano-Gallego

Summary: This study investigated the seroprevalence of canine leishmaniosis in apparently healthy dogs in different areas of Spain. The results showed significant regional variations in the infection rates, with the highest prevalence in the Southeast and the lowest in the North.

VETERINARY MEDICINE AND SCIENCE (2023)

Add to Collection

Article Veterinary Sciences

Exploring the Relationship between Neutrophil Activation and Different States of Canine L. infantum Infection: Nitroblue Tetrazolium Test and IFN-γ

Carles Blasi-Brugue, Iciar Martinez-Florez, Marta Baxarias, Joan del Rio-Velasco, Laia Solano-Gallego

Summary: This study investigated the role of neutrophils in canine leishmaniosis and found that neutrophil activation was higher in dogs with mild disease and healthy-seropositive dogs. A relationship between neutrophil activation and the production of IFN-gamma was also observed.

VETERINARY SCIENCES (2023)

Add to Collection

Article Veterinary Sciences

The Italian Network of Laboratories for Veterinary Oncology (NILOV) 2.0: Improving Knowledge on Canine Tumours

Maria Ines Crescio, Giuseppe Ru, Luca Aresu, Elena Bozzetta, Maria Giovanna Cancedda, Katia Capello, Massimo Castagnaro, Azzurra Carnio, Cristiano Cocumelli, Barbara Degli Uberti, Claudia Eleni, Greta Foiani, Niccolo Fonti, Lucia Rita Gibelli, Lorella Maniscalco, Elisabetta Manuali, Valentina Moccia, Orlando Paciello, Antonio Petrella, Antonio Petrini, Alessandro Poli, Roberto Puleio, Elisabetta Razzuoli, Paola Scaramozzino, Katia Varello, Marta Vascellari, Valentina Zappulli, Angelo Ferrari

Summary: This study described the data collected by The Italian Network of Laboratories for Veterinary Oncology in the first 9 years of activity, analyzing the frequency of tumour sites in dogs and considering risk factors. The results highlighted differences in tumour sites and potential role of risk factors. This emphasizes the importance of animal cancer registration initiatives to deepen knowledge of tumour epidemiology in dogs and humans.

VETERINARY SCIENCES (2022)

Add to Collection

No Data Available

© Peeref 2019-2024. All rights reserved.