Article
Neurosciences
Yanxiao Li, Yee Ling Ng, Manish D. Paranjpe, Qi Ge, Fengyun Gu, Panlong Li, Shaozhen Yan, Jie Lu, Xiuying Wang, Yun Zhou
Summary: This study aimed to improve the statistical power in detecting changes in brain glucose metabolism, amyloid, and tau deposition in Alzheimer's disease studies by using a reference tissue-based quantification approach. The results showed that the tracer-specific reference tissue improved the detection of PET SUVR changes, which is beneficial for early diagnosis, disease progression monitoring, and therapeutic response in Alzheimer's disease.
HUMAN BRAIN MAPPING
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Jin Qi, Elizabeth Kurian, Orhan K. oez
Summary: Hibernomas are rare benign tumors originating from fetal brown adipose tissue. They can occur in various parts of the body, with thigh, shoulder, back, and neck being the most common locations, and are rarely found in the abdominal cavity, retroperitoneum, breast, bones, scrotum, and perirectum. We present a case of a 58-year-old woman with a mediastinal mass, who was incidentally found to have an FDG-avid fat-containing lesion in the omentum abutting the stomach.
CLINICAL NUCLEAR MEDICINE
(2023)
Review
Immunology
Ilaria Mormile, Francesca Mosella, Piergiorgio Turco, Filomena Napolitano, Amato de Paulis, Francesca Wanda Rossi
Summary: Calcinosis is a severe complication of autoimmune disorders, including types like calcinosis cutis and calciphylaxis. Calcification of damaged tissues in the presence of normal calcium and phosphate levels is commonly associated with autoimmune diseases. Calciphylaxis, characterized by vascular calcifications and thrombosis, is also related to autoimmune conditions. It is important for physicians to be aware of the clinical presentation and management of calcinosis in order to choose appropriate treatment and prevent long-term complications.
Article
Radiology, Nuclear Medicine & Medical Imaging
Sung Ryul Shim, Seong-Jang Kim
Summary: This study evaluated the diagnostic accuracies of F-18-FDG PET or PET/CT for Merkel cell carcinoma (MCC) through a systematic review and meta-analysis. The results showed that F-18-FDG PET/CT had excellent performance in diagnosing MCC and could be useful for exclusion and confirmation of the disease. Further large multicenter studies are needed to validate its diagnostic accuracy.
CLINICAL NUCLEAR MEDICINE
(2022)
Review
Medicine, General & Internal
Anna Wajda, Larysa Sivitskaya, Agnieszka Paradowska-Gorycka
Summary: NGS technologies have played a crucial role in the study and diagnosis of autoimmune diseases, particularly in autoimmune connective tissue diseases, with panels, whole-genome and -exome sequencing, and HLA widely used. Despite the wide scope of research areas, it seems that epigenetic influence on the development of systemic autoimmune diseases may set important trends for future studies.
JOURNAL OF CLINICAL MEDICINE
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Yun Chen, Shan Zheng, Zenan Wu, Yanmin Lin, Weibing Miao
Summary: A 76-year-old man with yellowish discoloration of sclera and skin for 2 months was referred for F-18-FDG PET/CT to characterize a mass in the pancreas. PET/CT images showed intense FDG uptake in the head of the pancreas, with a lymph nodal mass in the hepatic hilar region, consistent with pancreatic malignancy. Histopathologic findings confirmed diffuse large B-cell lymphoma with no evidence of adenocarcinoma.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Respiratory System
Vincent Cottin, Luca Richeldi, Ivan Rosas, Maria Otaola, Jin Woo Song, Sara Tomassetti, Marlies Wijsenbeek, Manuela Schmitz, Carl Coeck, Susanne Stowasser, Rozsa Schlenker-Herceg, Martin Kolb
Summary: In patients with progressive fibrosing ILDs, the effect of nintedanib in reducing FVC decline was not affected by the use of immunomodulatory therapies, allowing for combination use of nintedanib with these therapies.
RESPIRATORY RESEARCH
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Abarnaa Sivapathasundaram, Nicolas Golse, Alina Pascale, Emmanuel Durand, Mylene Sebagh, Florent L. Besson
Summary: Contrary to common belief, F-18-FDG/F-18-choline dual-tracer PET behavior is not a relevant surrogate of tumor differentiation in hepatocellular carcinoma (HCC). Future multitracer PET studies are necessary to improve our understanding of their biological significance in this field.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Nutrition & Dietetics
Paola Tiberio, Lidija Antunovic, Mariangela Gaudio, Alessandro Vigano, Manuela Pastore, Chiara Miggiano, Flavia Jacobs, Chiara Benvenuti, Elisabetta Farina, Arturo Chiti, Armando Santoro, Rita De Sanctis
Summary: The impact of patients' eating habits on breast cancer management and inflammation has been investigated. The study found positive correlations between bowel [18]F-FDG uptake and pro-inflammatory drinks and foods, as well as a negative correlation between rectum SUVmean and anti-inflammatory foods. In addition, colon SUVmean was significantly lower in patients with pCR. This suggests that PET scan could be used to identify patients with unhealthy behaviors.
Review
Oncology
Domenico Albano, Giorgio Treglia, Francesco Dondi, Anna Calabro, Alessio Rizzo, Salvatore Annunziata, Luca Guerra, Silvia Morbelli, Alessandra Tucci, Francesco Bertagna
Summary: The new biomarker Dmax, which measures the maximal distance between the two farthest hypermetabolic PET lesions, has shown high accuracy as a prognostic factor in lymphoma patients. Most studies have demonstrated the significant predictive value of Dmax in predicting progression-free survival and overall survival.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Himanshu Bansal, Mudalsha Ravina, Siddhartha Nanda, Tinu Thadiyananickal Lukose, Sarin Krishna
Summary: This case report describes a patient with cervical cancer who showed intense FDG uptake in white adipose tissue on F-18-FDG PET/CT scan, which was later attributed to herbal medication containing corticosteroids for treating herpes zoster infection.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Respiratory System
Franck F. Rahaghi, Vivien M. Hsu, Robert J. Kaner, Maureen D. Mayes, Ivan O. Rosas, Rajan Saggar, Virginia D. Steen, Mary E. Strek, Elana J. Bernstein, Nitin Bhatt, Flavia V. Castelino, Lorinda Chung, Robyn T. Domsic, Kevin R. Flaherty, Nishant Gupta, Bashar Kahaleh, Fernando J. Martinez, Lee E. Morrow, Teng Moua, Nina Patel, Oksana A. Shlobin, Brian D. Southern, Elizabeth R. Volkmann, Dinesh Khanna
Summary: This study aimed to develop consensus recommendations on the management of patients with SSc-ILD based on expert physician insights. A modified Delphi process was completed by pulmonologists and rheumatologists, resulting in the generation of a management algorithm that addresses the current gaps in management approaches.
RESPIRATORY RESEARCH
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
David J. Liesker, Stijn Legtenberg, Paola A. Erba, Andor W. J. M. Glaudemans, Clark J. Zeebregts, Jean-Paul P. M. De Vries, Nabil Chakfe, Ben R. Saleem, Riemer H. J. A. Slart
Summary: This study aimed to assess the variability of [F-18]FDG-PET/LDCT reporting in suspected VGEI using a standardized reporting format. The results showed that less than half of the reports met all the pre-selected criteria, and the incompleteness of reports led to lower sensitivity and specificity.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Sing Hon Kwok, Frankie Choi
Summary: In this report, a 54-year-old woman with a 3-month history of skin rash and bilateral hearing loss is presented. Multiple investigations failed to diagnose relapsing polychondritis, until F-18-FDG PET/CT showed a characteristic FDG activity pattern-the oto-rhino-tracheobronchial triad. The patient was subsequently diagnosed and treated for relapsing polychondritis. The second FDG PET/CT revealed differential response in different disease sites, leading to an escalation of treatment.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Oncology
Lidija Antunovic, Alessia Artesani, Alessandro Vigano, Arturo Chiti, Armando Santoro, Martina Sollini, Silvia D. Morbelli, Rita De Sanctis
Summary: This study aimed to examine brain metabolic patterns on [F-18]Fluorodeoxyglucose ([F-18]FDG) positron emission tomography (PET) in breast cancer (BC), comparing patients with tension-type headache (TTH), migraine (MiG), and those without headache. The results showed that headache patients exhibited hypometabolism in specific brain regions before neoadjuvant chemotherapy (NAC) and headache patients with a good response to NAC showed hypermetabolic brain regions in the anterior medial frontal cortex.
Review
Rheumatology
Masayoshi Harigai, Kenji Nagasaka, Koichi Amano, Masashi Bando, Hiroaki Dobashi, Tamihiro Kawakami, Kan Kishibe, Yohko Murakawa, Joichi Usui, Takashi Wada, Eiichi Tanaka, Eishu Nango, Takeo Nakayama, Michi Tsutsumino, Kunihiro Yamagata, Sakae Homma, Yoshihiro Arimua
MODERN RHEUMATOLOGY
(2019)
Article
Urology & Nephrology
Kunihiro Yamagata, Joichi Usui, Michio Nagata, Hitoshi Sugiyama, Ken-ei Sada, Eri Muso, Masayoshi Harigai, Koichi Amano, Tatsuya Atsumi, Shouichi Fujimoto, Yukio Yuzawa, Masaki Kobayashi, Takao Saito, Takafumi Ito, Nobuhito Hirawa, Sakae Homma, Hiroaki Dobashi, Naotaka Tsuboi, Akihiro Ishizu, Yoshihiro Arimura, Hirofumi Makino, Seiichi Matsuo, Yoshinari Takasaki, Shogo Banno, Takahiko Sugihara, Yohko Murakawa, Hitoshi Hasegawa, Atsushi Komatsuda, Satoshi Ito, Takao Fujii, Atsushi Kawakami, Izaya Nakaya, Masahiro Yamamura, Masaaki Nakano, Kosaku Nitta, Makoto Ogura, Taio Naniwa, Shoichi Ozaki, Junichi Hirahashi, Noriyoshi Ogawa, Tatsuo Hosoya, Takashi Wada, Satoshi Horikoshi, Yasushi Kawaguchi, Taichi Hayashi, Masaharu Yoshida, Tsuyoshi Watanabe, Daijo Inaguma, Kazuhiko Tsuruya, Noriyuki Homma, Yasunori Okada, Tsutomu Takeuchi, Naoki Nakagawa, Shinichi Takeda, Ritsuko Katabuchi, Masayuki Iwano
CLINICAL AND EXPERIMENTAL NEPHROLOGY
(2019)
Article
Rheumatology
Hiromi Shimada, Tomohiro Kameda, Kenji Kanenishi, Nobuyuki Miyatake, Shusaku Nakashima, Risa Wakiya, Mikiya Kato, Taichi Miyagi, Mai Mahmoud Fahmy Mansour, Toshiyuki Hata, Norimitsu Kadowaki, Hiroaki Dobashi
CLINICAL RHEUMATOLOGY
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Aika Suzuki, Susumu Sakamoto, Atsuko Kurosaki, Yasuyuki Kurihara, Keita Satoh, Yusuke Usui, Toshihiro Nanki, Yoshihiro Arimura, Hirofumi Makino, Yasunori Okada, Masayoshi Harigai, Kunihiro Yamagata, Hitoshi Sugiyama, Hiroaki Dobashi, Akihiro Ishizu, Naotake Tsuboi, Joichi Usui, Ken-ei Sada, Sakae Homma
AMERICAN JOURNAL OF ROENTGENOLOGY
(2019)
Article
Rheumatology
R. Wakiya, T. Kameda, K. Ueeda, S. Nakashima, H. Shimada, M. F. Mansour, M. Kato, T. Miyagi, N. Miyatake, N. Kadowaki, H. Dobashi
Article
Rheumatology
Yoshiya Tanaka, Koji Oba, Takao Koike, Nobuyuki Miyasaka, Tsuneyo Mimori, Tsutomu Takeuchi, Shintaro Hirata, Eiichi Tanaka, Hidekata Yasuoka, Yuko Kaneko, Kosaku Murakami, Tomohiro Koga, Kazuhisa Nakano, Koichi Amano, Kazuyasu Ushio, Tatsuya Atsumi, Masayuki Inoo, Kazuhiro Hatta, Shinichi Mizuki, Shouhei Nagaoka, Shinichiro Tsunoda, Hiroaki Dobashi, Nao Horie, Norihiro Sato
ANNALS OF THE RHEUMATIC DISEASES
(2020)
Review
Cardiac & Cardiovascular Systems
Mitsuaki Isobe, Koichi Amano, Yoshihiro Arimura, Akihiro Ishizu, Shuichi Ito, Shinya Kaname, Shigeto Kobayashi, Yoshinori Komagata, Issei Komuro, Kimihiro Komori, Kei Takahashi, Kazuo Tanemoto, Hitoshi Hasegawa, Masayoshi Harigai, Shouichi Fujimoto, Tatsuhiko Miyazaki, Tetsuro Miyata, Hidehiro Yamada, Akitoshi Yoshida, Takashi Wada, Yoshinori Inoue, Haruhito A. Uchida, Hideki Ota, Takahiro Okazaki, Mitsuho Onimaru, Tamihiro Kawakami, Reiko Kinouchi, Atsushi Kurata, Hisanori Kosuge, Ken-ei Sada, Kunihiro Shigematsu, Eiichi Suematsu, Eijun Sueyoshi, Takahiko Sugihara, Hitoshi Sugiyama, Mitsuhiro Takeno, Naoto Tamura, Michi Tsutsumino, Hiroaki Dobashi, Yoshikazu Nakaoka, Kenji Nagasaka, Yasuhiro Maejima, Hajime Yoshifuji, Yoshiko Watanabe, Shoichi Ozaki, Takeshi Kimura, Hiroshi Shigematsu, Keiko Yamauchi-Takihara, Toyoaki Murohara, Shin-ichi Momomura
CIRCULATION JOURNAL
(2020)
Article
Rheumatology
Haruki Watanabe, Ken-Ei Sada, Yoshinori Matsumoto, Masayoshi Harigai, Koichi Amano, Shouichi Fujimoto, Hiroaki Dobashi, Yukio Yuzawa, Kunihiro Yamagata, Eri Muso, Yoshihiro Arimura, Hirofumi Makino, Hitoshi Sugiyama, Seiichi Matsuo, Yoshinari Takasaki, Akihiro Ishizu, Tatsuya Atsumi, Takao Fujii, Yasunori Okada, Sakae Homma, Naotake Tsuboi, Joichi Usui, Shunichi Kumagai, Takahiko Sugihara, Yohko Murakawa, Shogo Banno, Hitoshi Hasegawa, Wako Yumura, Hiroaki Matsubara, Masaharu Yoshida, Kensei Katsuoka, Noriyoshi Ogawa, Atsushi Komatsuda, Satoshi Ito, Atsushi Kawakami, Izaya Nakaya, Takao Saito, Takafumi Ito, Nobuhito Hirawa, Masahiro Yamamura, Masaaki Nakano, Kosaku Nitta, Makoto Ogura, Taio Naniwa, Shoichi Ozaki, Junichi Hirahashi, Tatsuo Hosoya, Takashi Wada, Satoshi Horikoshi, Yasushi Kawaguchi, Taichi Hayashi, Tsuyoshi Watanabe, Daijo Inaguma, Kazuhiko Tsuruya, Noriyuki Homma, Tsutomu Takeuchi, Naoki Nakagawa, Shinichi Takeda, Ritsuko Katafuchi, Masayuki Iwano, Masaki Kobayashi, Hidehiro Yamada
Summary: The study evaluated the effectiveness of cyclophosphamide for patients with microscopic polyangiitis and granulomatosis with polyangiitis. The results suggest that concomitant use of cyclophosphamide may improve glucocorticoid remission by Month 6 in MPO-ANCA-positive patients, potentially sparing glucocorticoid consumption.
MODERN RHEUMATOLOGY
(2021)
Article
Medicine, General & Internal
Nobuhiro Tahara, Hiroaki Dobashi, Keiichi Fukuda, Masanori Funauchi, Masaru Hatano, Satoshi Ikeda, Shuji Joho, Yasuki Kihara, Takahisa Kondo, Masakazu Matsushita, Tohru Minamino, Norifumi Nakanishi, Yoshiaki Okano, Yukio Ozaki, Tsutomu Saji, Satoshi Sakai, Nobuhiro Tanabe, Hiroshi Watanabe, Hidehiro Yamada, Koichiro Yoshioka, Motonori Hatta, Shigetake Sasayama
CURRENT MEDICAL RESEARCH AND OPINION
(2020)
Article
Rheumatology
S. Fukui, K. Ichinose, K-E Sada, J. Miyamoto, M. Harigai, K. Amano, T. Atsumi, Y. Takasaki, H. Dobashi, Y. Arimura, H. Hasegawa, Y. Yuzawa, K. Yamagata, N. Tsuboi, S. Maruyama, S. Matsuo, H. Makino, T. Maeda, A. Kawakami
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
(2020)
Article
Rheumatology
Yoshiyuki Abe, Keigo Saeki, Hiroaki Dobashi, Tamihiro Kawakami, Taichi Hayashi, Masaki Kobayashi, Shinya Kaname, Masayoshi Harigai, Naoto Tamura
Summary: Based on the analysis of data from the Ministry of Health, Labour and Welfare in Japan, it was found that from 2003 to 2013, the disease activity of MRA patients decreased and social productivity improved.
MODERN RHEUMATOLOGY
(2021)
Article
Transplantation
Yuki Yokoe, Naotake Tsuboi, Takahiro Imaizumi, Akimitsu Kitagawa, Munetoshi Karasawa, Takaya Ozeki, Nobuhide Endo, Yuriko Sawa, Sawako Kato, Takayuki Katsuno, Shoichi Maruyama, Kunihiro Yamagata, Joichi Usui, Michio Nagata, Ken-Ei Sada, Hitoshi Sugiyama, Koichi Amano, Yoshihiro Arimura, Tatsuya Atsumi, Yukio Yuzawa, Hiroaki Dobashi, Yoshinari Takasaki, Masayoshi Harigai, Hitoshi Hasegawa, Hirofumi Makino, Seiichi Matsuo
Summary: The detection of leukocyte-derived CD11b and CD163 in urine may reflect renal inflammation in ANCA-GN, and CD11b at diagnosis can predict the recovery rate after the treatment of ANCA-GN.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Medicine, General & Internal
Risa Wakiya, Tomohiro Kameda, Shusaku Nakashima, Hiromi Shimada, Mai Mahmoud Fahmy Mansour, Mikiya Kato, Taichi Miyagi, Norimitsu Kadowaki, Hiroaki Dobashi
Review
Immunology
Yoshiya Tanaka, Atsuko Murashima, Tatsuya Atsumi, Hiroaki Dobashi, Yohko Murakawa, Shigeki Momohara, Haruna Kawaguchi, Shinji Tanigaki, Shintaro Makino, Shigeru Saito
Summary: The introduction of biologic therapies and a treat-to-target approach has improved outcomes for women with rheumatoid arthritis (RA) who wish to become pregnant. However, guidelines for reproductive health management in female RA patients are lacking.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY
(2023)
Article
Rheumatology
Takahiko Sugihara, Hitoshi Hasegawa, Haruhito A. Uchida, Hajime Yoshifuji, Yoshiko Watanabe, Eisuke Amiya, Yasuhiro Maejima, Masanori Konishi, Yohko Murakawa, Noriyoshi Ogawa, Shunsuke Furuta, Yasuhiro Katsumata, Yoshinori Komagata, Taio Naniwa, Takahiro Okazaki, Yoshiya Tanaka, Tsutomu Takeuchi, Yoshikazu Nakaoka, Yoshihiro Arimura, Masayoshi Harigai, Mitsuaki Isobe
ARTHRITIS RESEARCH & THERAPY
(2020)
