Journal
JAPANESE JOURNAL OF APPLIED PHYSICS
Volume 53, Issue 1, Pages -Publisher
IOP PUBLISHING LTD
DOI: 10.7567/JJAP.53.01AF03
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Funding
- National Research Foundation of Korea (NRF)
- Korea government (MEST) [20090093908]
- Gyeonggi-do Regional Research Center (GRRC) for the Bionano Sensor at Gachon University
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Less toxic zinc selenide (ZnSe) quantum dots were synthesized in the cavity of the apoferritin from horse spleen (HsAFr), and the two-dimensional ZnSe-ferritin nanodots were prepared on modified silicon surface. For utilizing the array as a biosensor, the photoluminescence (PL) spectrum change was investigated by accompanying its conjugation reaction with a neurotransmitter dopamine. When the array was conjugated with dopamine, a significant quenching of the fluorescence occurred and the PL intensity was a linear function of the dopamine concentration in the range of 0-0.6 mu M. Accordingly, the ZnSe-ferritin nanodot arrays can be employed as a useful sensing media for tiny concentration of dopamine. (C) 2014 The Japan Society of Applied Physics
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