Article
Oncology
Kentaro Hayashi, Makiko Mori, Youhei Sanmoto, Hironobu Oiki, Tetsuya Ishimaru, Yuki Arakawa, Katsuyoshi Koh, Hiroshi Kawashima
Summary: Background biopsies for diagnosis before chemotherapy are common in children with malignant solid tumors. This study aimed to summarize the relationship between chemotherapy timing and postoperative surgical complications. The results suggest that the rate of postoperative surgical complications related to biopsy seems acceptable, even when chemotherapy was initiated in the early postoperative period.
PEDIATRIC BLOOD & CANCER
(2023)
Review
Medicine, General & Internal
Abel Botelho Quaresma, Fernanda da Silva Barbosa Barauna, Fabio Vieira Teixeira, Rogerio Saad-Hossne, Paulo Gustavo Kotze
Summary: Most studies have not shown increased complication rates after abdominal surgical procedures in UC patients with preoperative exposure to biologics. Further prospective studies are needed to better establish the impact of preoperative biologics on surgical complications in UC.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Magdalena Walicka, Monika Puzianowska-Kuznicka, Marcin Chlebus, Andrzej Sliwczynski, Melania Brzozowska, Daniel Rutkowski, Lidia Kania, Marcin Czech, Andrzej Jacyna, Edward Franek
Summary: This study assessed in-hospital non-surgical mortality rate in a large group of patients, finding that the rate was approximately 4% and significantly increased with age, with patients suffering from respiratory diseases having the highest mortality regardless of age.
ARCHIVES OF MEDICAL SCIENCE
(2021)
Article
Geriatrics & Gerontology
X. Chen, Z. Liao, Y. Shen, B. Dong, L. Hou, Q. Hao
Summary: The study showed that pre-admission waiting time was associated with postoperative complications, length of stay, and hospitalization costs among older Chinese patients undergoing surgery to treat hip fractures.
JOURNAL OF NUTRITION HEALTH & AGING
(2021)
Article
Surgery
Nader N. Massarweh, Vivi W. Chen, Tracey Rosen, Peter A. Richardson, Alex H. S. Harris, Laura A. Petersen
Summary: The study found moderate correlations between mortality, morbidity, and other perioperative outcomes at the hospital level after noncardiac surgery. It is challenging to accurately identify high or low performing hospitals using a single measure, suggesting that evaluating performance across a range of individual measures may be more effective.
JOURNAL OF SURGICAL RESEARCH
(2021)
Article
Health Care Sciences & Services
Samer Haidar, Reynaldo Vazquez, Goran Medic
Summary: This study aimed to compare the length of stay, hospital costs, and hospital revenues for Medicare patients with and without potentially preventable postoperative complications. The analysis revealed that patients with complications had longer hospital stays, higher costs, and negative impact on hospital profitability and patient quality of life. Quality initiatives targeting complication reduction can be highly valuable for improving patient outcomes and hospital finances.
JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH
(2023)
Article
Anesthesiology
Luca J. Wachtendorf, Maximilian Sebastian Schaefer, Peter Santer, Omid Azimaraghi, Salameh Sameh Obeidat, Sabine Friedrich, Liana Zucco, Albert Woo, Sarah Nabel, Eswar Sundar, Matthias Eikermann, Satya Krishna Ramachandran
Summary: The study showed that preoperative administration of gabapentinoids can reduce the risk of hospital readmission and postoperative respiratory complications in patients, partly due to lower intraoperative opioid utilization.
JOURNAL OF CLINICAL ANESTHESIA
(2021)
Article
Oncology
Nina L. Eng, Danielle E. Mustin, Brendan P. Lovasik, Michael K. Turgeon, Adriana C. Gamboa, Mihir M. Shah, Kenneth Cardona, Juan M. Sarmiento, Maria C. Russell, Shishir K. Maithel, Jeffrey M. Switchenko, David A. Kooby
Summary: Preoperative biopsy of duodenal adenomas has a high false-negative rate for malignancy, and pancreatoduodenectomy for duodenal adenoma is associated with higher complication rates compared to pancreatic ductal adenocarcinoma. These findings suggest careful consideration should be given when deciding between observation and pancreatoduodenectomy for duodenal adenoma patients, especially in younger patients without biliary obstruction.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Surgery
Sheraz Markar, Giola Santoni, John Maret-Ouda, Miia Artama, Martti Farkkila, Elsebeth Lynge, Eero Pukkala, Eivind Ness-Jensen, My Von Euler-Chelpin, Jesper Lagergren
Summary: Based on data from Denmark, Finland, and Sweden, the study found that higher hospital volume did not decrease the rates of endoscopic and surgical re-interventions after antireflux surgery, indicating that centralization of surgery may not reduce postoperative complications or recurrence rates.
Article
Medicine, General & Internal
Michal Elbaum, Marcin Kaluzny, Aleksandra Jawiarczyk-Przybylowska, Beata Wojtczak, Grzegorz Zielinski, Marek Bolanowski
Summary: Uncontrolled acromegaly is associated with increased morbidity and mortality. The incidence of comorbidities and complications in acromegaly patients is high, with the most common being arterial hypertension, multinodular goiter, lipid disorders, hypopituitarism, and degenerative changes. Active acromegaly has a higher incidence of complications compared to treated groups. Successfully cured patients have significantly fewer complications than pharmacologically controlled patients and patients with active acromegaly.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Adrian Diaz, Joal D. Beane, J. Madison Hyer, Diamantis Tsilimigras, Timothy M. Pawlik
Summary: This study aimed to investigate the impact of high-versus low-quality hospitals on the risk of adverse outcomes among patients undergoing hepatopancreatic surgery relative to social vulnerability. The results showed that socially vulnerable patients had considerably better outcomes at high-quality hospitals.
Review
Oncology
Lu Zhao, Na Wang, Dou Zhang, Yingjie Jia, Fanming Kong
Summary: The RET gene plays important roles in the nervous system and various tissues. RET mutation is associated with cell proliferation, invasion, and migration. Many invasive tumors show changes in RET, and recent therapeutic advancements utilizing selpercatinib and pralsetinib have shown promising efficacy. However, the development of acquired resistance needs further exploration. This article provides a systematic review of the RET gene and its biology, as well as its oncogenic role in multiple cancers. Recent advances in RET treatment and drug resistance mechanisms are also summarized.
FRONTIERS IN ONCOLOGY
(2023)
Article
Green & Sustainable Science & Technology
Om Raj Katoch
Summary: Globally, there is a growing momentum toward achieving universal access to clean energy, particularly electricity, as it plays a crucial role in improving the overall quality of life. In many countries, governments are actively involved in enhancing electricity access, but this effort can put strain on state finances, leading to increased fiscal deficits. This paper investigates the relationship between power expenditure and state finances in Jammu and Kashmir, India, and suggests targeted subsidies, small energy projects, and energy-saving technologies to reduce the pressure on state finances caused by enormous domestic power subsidies.
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY
(2023)
Article
Surgery
Caitlin B. Finn, Chris Wirtalla, Tory Mascuilli, Lauren N. Krumeich, Heather Wachtel, Douglas Fraker, Rachel R. Kelz
Summary: The study evaluated the impact of referring older adults with thyroid cancer to higher-quality hospitals for surgery. It was found that referral to higher-quality hospitals resulted in a lower rate of postoperative complications.
Article
Psychology, Social
Joe J. Gladstone, Emily N. Garbinsky, Cassie Mogilner
Summary: The decision of whether to pool finances in a relationship can have an impact on relationship satisfaction and the likelihood of breakup, especially for couples with scarce financial resources. Joining bank accounts benefits couples by increasing relationship satisfaction and reducing the risk of separation.
JOURNAL OF PERSONALITY AND SOCIAL PSYCHOLOGY
(2022)
Letter
Surgery
Barry Rosenberg, Bennett Lane, Atul Gawande
Letter
Oncology
Joshua Z. Drago, Bennett Lane, Jonathan Kochav, Bruce Chabner
Article
Pediatrics
Samuel Rice-Townsend, Atul Gawande, Stuart Lipsitz, Shawn J. Rangel
JOURNAL OF PEDIATRIC SURGERY
(2013)
Article
Pediatrics
Kendra G. Bowman, Goran Jovic, Shawn Rangel, William R. Berry, Atul A. Gawande
JOURNAL OF PEDIATRIC SURGERY
(2013)
Article
Statistics & Probability
Stuart R. Lipsitz, Garrett M. Fitzmaurice, Scott E. Regenbogen, Debajyoti Sinha, Joseph G. Ibrahim, Atul A. Gawande
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS
(2013)
Article
Emergency Medicine
Bennett H. Lane, Peter J. Mallow, Maria B. Hooker, Edmond Hooker
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2020)
Article
Emergency Medicine
Andrew H. Ruffner, Rachel M. Ancona, Catherine Hamilton, Francisco J. Fernandez, Kiran A. Faryar, Bennett H. Lane, Michael S. Lyons
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2020)
Article
Emergency Medicine
Brittany E. Punches, Summer Soliman, Caroline E. Freiermuth, Bennett H. Lane, Michael S. Lyons
JOURNAL OF EMERGENCY NURSING
(2020)
Article
Emergency Medicine
Bennett H. Lane, Michael S. Lyons, Uwe Stolz, Rachel M. Ancona, Richard J. Ryan, Caroline E. Freiermuth
Summary: This study assessed the fidelity to naloxone practice recommendations in a cohort of Emergency Department patients with suspected opioid use disorder. The results showed that most patients who received interventions targeted at OUD did not receive naloxone upon discharge, suggesting barriers to naloxone provision.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Editorial Material
Medicine, General & Internal
Eric Goralnick, Christoph Kaufmann, Atul A. Gawande
Summary: Mass-vaccination sites present a logical solution to the challenges of Covid-19 vaccination, and early adopters have learned critical lessons for achieving population-wide vaccination.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Editorial Material
Emergency Medicine
Bennett H. Lane, Rachel M. Ancona, Natalie Kreitzer, Elizabeth Leenellett
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Nursing
Bennett H. Lane, Rachel M. Ancona, Michael S. Lyons, Brittany E. Punches
Summary: Emergency departments (EDs) are important potential sites for public health screening programs, but implementing such programs can be challenging due to system-level and individual provider-level barriers. A cross-sectional evaluation of a nurse-driven, triage-based hepatitis C virus (HCV) screening program in an urban, academic ED found wide variation in individual nurse participation, indicating that individual-level barriers may be a more significant obstacle to ED screening than previously recognized. Further research should focus on addressing staff knowledge, beliefs, attitudes, and motivation in addition to resource availability and procedural streamlining.
ADVANCED EMERGENCY NURSING JOURNAL
(2021)
Review
Emergency Medicine
Bennett H. Lane
EMERGENCY CARE JOURNAL
(2016)
Letter
Medicine, General & Internal
Atul A. Gawande, Alexander F. Arriaga
NEW ENGLAND JOURNAL OF MEDICINE
(2013)