Modular Synthesis of Heparin-Related Tetra-, Hexa- and Octasaccharides with Differential O-6 Protections: Programming for Regiodefined 6-O-Modifications

Interactions That Influence the Binding of Synthetic Heparan Sulfate Based Disaccharides to Fibroblast Growth Factor-2

(2014) Yi-Ching Li et al.   ACS Chemical Biology

Synthesis of a heparin-related GlcN–IdoA sulfation-site variable disaccharide library and analysis by Raman and ROA spectroscopy

(2014) Gavin J. Miller et al.   CARBOHYDRATE RESEARCH

Homogeneous low-molecular-weight heparins with reversible anticoagulant activity

(2014) Yongmei Xu et al.   Nature Chemical Biology

Synthesis of a Targeted Library of Heparan Sulfate Hexa- to Dodecasaccharides as Inhibitors of β-Secretase: Potential Therapeutics for Alzheimer’s Disease

(2013) Ralf Schwörer et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthetic heparin and heparan sulfate oligosaccharides and their protein interactions

(2013) Medel Manuel L Zulueta et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Pathophysiology of heparan sulphate: many diseases, few drugs

(2013) U. Lindahl et al.   JOURNAL OF INTERNAL MEDICINE

Toward the Solid-Phase Synthesis of Heparan Sulfate Oligosaccharides: Evaluation of Iduronic Acid and Idose Building Blocks

(2013) Nerea Guedes et al.   JOURNAL OF ORGANIC CHEMISTRY

Fluorous Supported Modular Synthesis of Heparan Sulfate Oligosaccharides

(2013) Chengli Zong et al.   ORGANIC LETTERS

Efficient chemical synthesis of heparin-like octa-, deca- and dodecasaccharides and inhibition of FGF2- and VEGF165-mediated endothelial cell functions

(2013) Gavin J. Miller et al.   Chemical Science

Tetrasaccharide iteration synthesis of a heparin-like dodecasaccharide and radiolabelling for in vivo tissue distribution studies

(2013) Steen U. Hansen et al.   Nature Communications

Endothelial Heparan Sulfate 6-O-Sulfation Levels Regulate Angiogenic Responses of Endothelial Cells to Fibroblast Growth Factor 2 and Vascular Endothelial Growth Factor

(2012) Cristina Ferreras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Divergent Synthesis of 48 Heparan Sulfate-Based Disaccharides and Probing the Specific Sugar–Fibroblast Growth Factor-1 Interaction

(2012) Yu-Peng Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

First Gram-Scale Synthesis of a Heparin-Related Dodecasaccharide

(2012) Steen U. Hansen et al.   ORGANIC LETTERS

Divergent Heparin Oligosaccharide Synthesis with Preinstalled Sulfate Esters

(2011) Gopinath Tiruchinapally et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of 3-O-sulfonated heparan sulfate octasaccharides that inhibit the herpes simplex virus type 1 host–cell interaction

(2011) Yu-Peng Hu et al.   Nature Chemistry

Chemoenzymatic Synthesis of Homogeneous Ultralow Molecular Weight Heparins

(2011) Y. Xu et al.   SCIENCE

Preactivation-Based, One-Pot Combinatorial Synthesis of Heparin-like Hexasaccharides for the Analysis of Heparin-Protein Interactions

(2010) Zhen Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancer

(2010) Benito Casu et al.   MATRIX BIOLOGY

Synthetic Heparan Sulfate Oligosaccharides Inhibit Endothelial Cell Functions Essential for Angiogenesis

(2010) Claire L. Cole et al.   PLoS One

Modular Synthesis of Heparan Sulfate Oligosaccharides for Structure−Activity Relationship Studies

(2009) Sailaja Arungundram et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY