Article
Virology
Pierluigi Francesco Salvo, Damiano Farinacci, Arturo Ciccullo, Vanni Borghi, Stefano Rusconi, Annalisa Saracino, William Gennari, Bianca Bruzzone, Ilaria Vicenti, Annapaola Callegaro, Antonio Di Biagio, Maurizio Zazzi, Simona Di Giambenedetto, Alberto Borghetti
Summary: This study compared the efficacy of darunavir-based regimens and dolutegravir-based regimens in clinical practice, with a focus on pre-treatment drug resistance mutations and HIV-1 subtype. The results showed that dolutegravir-based regimens had a superior efficacy in terms of time to virological failure compared to darunavir-based regimens, and pre-treatment drug resistance mutations and HIV-1 subtype influenced the treatment outcomes.
Article
Biology
Eva Liliane Ujeneza, Wilfred Ndifon, Shobna Sawry, Geoffrey Fatti, Julien Riou, Mary-Ann Davies, Martin Nieuwoudt
Summary: This study introduces a novel 'ratio' model to explore the long-term effects of the growing population of HIV-treated individuals in Southern Africa on both individuals and the public health sector. Results show that children were closer to healthy CD4+ counts compared to adults, and adults had a higher CD4+ growth rate post-ART initiation.
Article
Oncology
Sang-Won Kim, Mison Chun, Yong Sik Jung, Young-Taek Oh, O. Kyu Noh, Oyeon Cho
Summary: The study identified traditionally underestimated risk groups for LR and suggested that BMI may diversely influence the rate of LR across intrinsic subtypes in Korean patients with breast cancer.
Article
Infectious Diseases
Paul Krogstad, Pearl Samson, Edward P. Acosta, Jack Moye, Ellen Townley, Sarah Bradford, Emily Brown, Kayla Denson, Bobbie Graham, Laura Hovind, Thucuma Sise, Hedy Teppler, Sisinyana Ruth Mathiba, Lee Fairlie, Jana L. Winckler, Gretchen Slade, Tammy Meyers
Summary: This study showed that 12 mg/kg twice daily raltegravir chewable tablets administered to HIV-positive children aged 4 weeks to <2 years concurrently receiving rifampin for TB treatment achieved pharmacokinetic targets safely.
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY
(2021)
Article
Public, Environmental & Occupational Health
Siphamandla B. B. Gumede, Annemarie M. J. Wensing, Samanta T. T. Lalla-Edward, John B. F. de Wit, W. D. Francois Venter, Hugo A. A. Tempelman, Lucas E. E. Hermans
Summary: A large proportion of people living with HIV in sub-Saharan Africa reside in rural areas, and limited knowledge is available about the enablers and barriers of adherence to antiretroviral treatment in these populations. In a cohort study of 501 adult PLHIV on ART at a rural South African treatment facility, we found that male gender, food insecurity, and depressive symptoms were independent risk factors for virological failure. Low household income and task-oriented coping were protective against suboptimal pill-count adherence. These findings highlight the importance of addressing the impact of socio-economic and psychosocial factors on treatment outcomes in rural settings.
Article
Infectious Diseases
Atul K. Patel, Ketan K. Patel, Sanjay Pujari, Jagdish K. Patel, Ambuj Kumar
Summary: The study shows that DTG is well tolerated and effective in suppressing HIV, with a low rate of persistent LLV across all antiretroviral treatment categories.
INDIAN JOURNAL OF SEXUALLY TRANSMITTED DISEASES AND AIDS
(2021)
Article
Immunology
Helene Pere, Aida Rascanu, Jerome LeGoff, Mathieu Matta, Frederic Bois, Olivier Lortholary, Valeriane Leroy, Odile Launay, Laurent Belec
INTERNATIONAL JOURNAL OF STD & AIDS
(2016)
Article
Infectious Diseases
S. Servais, N. Dumontier, L. Biard, N. Schnepf, M. Resche-Rigon, R. Peffault de Latour, C. Scieux, M. Robin, M. Meunier, A. Xhaard, F. Sicre de Fontbrune, J. Le Goff, G. Socie, F. Simon, M. -C. Mazeron
CLINICAL MICROBIOLOGY AND INFECTION
(2016)
Article
Infectious Diseases
M. Salmona, A. Caporossi, P. Simmonds, M. -A. Thelu, K. Fusillier, S. Mercier-Delarue, N. De Castro, J. LeGoff, M. -L. Chaix, O. Francois, F. Simon, P. Morand, S. Larrat, S. Maylin
CLINICAL MICROBIOLOGY AND INFECTION
(2016)
Article
Infectious Diseases
Maud Salmona, Slim Fourati, Linda Feghoul, Catherine Scieux, Aline Thiriez, Francois Simon, Matthieu Resche-Rigon, Jerome LeGoff
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
(2016)
Article
Virology
Sebastien Fouere, Benedicte Chaine, Sarah Maylin, Marine Minier, Pascale Vallee, Catherine Scieux, Francois Lassau, Jerome Legoff, Michel Janier
JOURNAL OF CLINICAL VIROLOGY
(2016)
Article
Infectious Diseases
M. A. Colombier, S. Amorim, M. Salmona, C. Thieblemont, J. Legoff, M. Lafaurie
JOURNAL OF INFECTION
(2017)
Article
Virology
Sarah Maylin, Linda Feghoul, Maud Salmona, Adel Herda, Severine Mercier-Delarue, Francois Simon, Jerome Legoff
JOURNAL OF MEDICAL VIROLOGY
(2017)
Article
Biochemistry & Molecular Biology
Jerome Legoff, Matthieu Resche-Rigon, Jerome Bouquet, Marie Robin, Samia N. Naccache, Severine Mercier-Delarue, Scot Federman, Erik Samayoa, Clotilde Rousseau, Prescillia Piron, Nathalie Kapel, Francois Simon, Gerard Socie, Charles Y. Chiu
Article
Critical Care Medicine
Jerome Legoff, Noemie Zucman, Virginie Lemiale, Djamel Mokart, Frederic Pene, Jerome Lambert, Achille Kouatchet, Alexandre Demoule, Francois Vincent, Martine Nyunga, Fabrice Bruneel, Adrien Contejean, Severine Mercier-Delarue, Antoine Rabbat, Christine Lebert, Pierre Perez, Anne-Pascale Meert, Dominique Benoit, Carole Schwebel, Merce Jourdain, Michael Darmon, Matthieu Resche-Rigon, Elie Azoulay
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2019)
Review
Hematology
Jerome Legoff, David Michonneau, Gerard Socie
SEMINARS IN HEMATOLOGY
(2020)
Article
Virology
Caroline Lefeuvre, Maud Salmona, Louise Bondeelle, Veronique Houdouin, Linda Feghoul, Herve Jacquier, Severine Mercier-Delarue, Anne Bergeron, Jerome LeGoff
Summary: This study found a higher incidence of LRTI-D caused by HPIV-3 in patients with HM and HSCT, with significantly higher viral loads in respiratory samples compared to non-hematological patients. These findings may help improve understanding of diagnosis and treatment for HM patients, and provide important insights for reducing complications caused by HPIV-3 infection in HSCT patients.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Respiratory System
Melanie Fromentin, Antoine Bridier-Nahmias, Jerome Legoff, Severine Mercier-Delarue, Noemie Ranger, Constance Vuillard, Julien Do Vale, Noemie Zucman, Antonio Alberdi, Jean-Damien Ricard, Damien Roux
Summary: The accuracy of the bacterial lung microbiome composition is highly dependent on the primers used for amplification of the 16s rRNA hypervariable sequence. Comparing two different primer pairs, results show that S-V4 primer pair provides better agreement with conventional microbiology for respiratory samples compared to R-V4 primer pair.
EXPERIMENTAL LUNG RESEARCH
(2022)
Article
Microbiology
Audrey Baron, Olivier Peyrony, Maud Salmona, Nadia Mahjoub, Sami Ellouze, Maud Anastassiou, Constance Delaugerre, Jean-Paul Fontaine, Sylvie Chevret, Jerome LeGoff, Linda Feghoul
Summary: The use of the ID NOW COVID-19 system in an emergency department was found to significantly reduce the length of stay for patients. The implementation of molecular point-of-care testing for SARS-CoV-2 resulted in faster results and decreased overcrowding in the emergency department. This study emphasizes the importance and benefits of COVID-19 molecular point-of-care testing in preventing overcrowding and facilitating patient care and isolation.
MICROBIOLOGY SPECTRUM
(2022)
Letter
Infectious Diseases
Guillaume Mellon, Emma Rubenstein, Meghann Antoine, Valentine Marie Ferre, Audrey Gabassi, Jean-Michel Molina, Constance Delaugerre, Jerome LeGoff
JOURNAL OF INFECTION
(2023)
Letter
Immunology
Jeremy Lafolie, Audrey Mirand, Maud Salmona, Alexandre Lautrette, Christine Archimbaud, Amelie Brebion, Christel Regagnon, Martine Chambon, Severine Mercier-Delarue, Jerome Le Goff, Cecile Henquell
EMERGING INFECTIOUS DISEASES
(2016)
