Review
Medicine, General & Internal
Mengjin Hu, Xiaojin Gao, Jingang Yang, Yuejin Yang
Summary: For patients treated with DESs, 3-month DAPT followed by P2Y12 inhibitor monotherapy may be the optimal antiplatelet strategy, while DAPT beyond 1 year reduces myocardial infarction at the expense of increased major bleeding.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Lars Jakobsen, Evald H. Christiansen, Phillip Freeman, Johnny Kahlert, Karsten Veien, Michael Maeng, Bent Raungaard, Julia Ellert, Anton B. Villadsen, Steen D. Kristensen, Ole Ahlehoff, Martin K. Christensen, Christian J. Terkelsen, Hans Erik Botker, Jens Aaroe, Troels Thim, Leif Thuesen, Ahmed Aziz, Ashkan Eftekhari, Rebekka V. Jensen, Nicolaj B. Stottrup, Jeppe G. Rasmussen, Anders Junker, Svend E. Jensen, Henrik S. Hansen, Lisette O. Jensen
Summary: The Combo stent (DTS) did not demonstrate noninferiority to the sirolimus-eluting Orsiro stent (SES) for target lesion failure at 12 months in an all-comers patient population. The SES was found to be superior to the DTS, mainly due to a higher risk of target lesion revascularization associated with the DTS.
Article
Cardiac & Cardiovascular Systems
Matteo Maurina, Mauro Chiarito, Pier Pasquale Leone, Luca Testa, Matteo Montorfano, Bernhard Reimers, Giovanni Esposito, Francesco Monti, Maurizio Ferrario, Azeem Latib, Antonio Colombo
Summary: This study failed to demonstrate the superiority of Abluminus DES+ over DP-EES in reducing neointimal hyperplasia in diabetic patients.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Medicine, General & Internal
David S. Eccleston, Enayet Chowdhury, Tony Rafter, Peter Sage, Alan Whelan, Christopher Reid, Danny Liew, MyNgan Duong, Nisha Schwarz, Stephen G. Worthley
Summary: This study aimed to compare long-term outcomes of new generation drug-eluting stents (DES) with other stents in Australia, and reported the clinical practice and outcomes of PCI with the Xience DES, finding that the use of Xience DES in Australia is consistent with international series.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Do-Yoon Kang, Jung-Min Ahn, Sung-Cheol Yun, Seung-Ho Hur, Yun-Kyeong Cho, Cheol Hyun Lee, Soon Jun Hong, Subin Lim, Sang-Wook Kim, Hoyoun Won, Jun-Hyok Oh, Jeong Cheon Choe, Young Joon Hong, Yong-Hoon Yoon, Hoyun Kim, Yeonwoo Choi, Jinho Lee, Young Won Yoon, Soo-Joong Kim, Jang-Ho Bae, Duk-Woo Park, Seung-Jung Park
Summary: This study demonstrated that OCT-guided PCI was noninferior to IVUS-guided PCI in terms of major cardiovascular events at one year in patients with significant coronary artery lesions, with a lower incidence of major procedural complications in the OCT group compared to the IVUS group. There was no significant difference in the incidence of contrast-induced nephropathy between the two groups.
Article
Cardiac & Cardiovascular Systems
Yong Zhu, Kesen Liu, Maolin Chen, Yan Liu, Ang Gao, Chengping Hu, Hong Li, Huagang Zhu, Hongya Han, Jianwei Zhang, Yingxin Zhao
Summary: The triglyceride-glucose (TyG) index is positively associated with in-stent restenosis (ISR) after drug-eluting stent (DES) implantation in patients with acute coronary syndrome (ACS). Higher TyG index is related to higher prevalence of DES-ISR in ACS patients.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Hyo-Soo Kim, Jeehoon Kang, Doyeon Hwang, Jung-Kyu Han, Han-Mo Yang, Hyun-Jae Kang, Bon-Kwon Koo, Seok Yeon Kim, Keun-Ho Park, Seung-Woon Rha, Won-Yong Shin, Hong-Seok Lim, Kyungil Park, Kyung Woo Park
Summary: The study demonstrated that in patients with acute coronary syndrome (ACS), durable polymer drug-eluting stents (DP-DES) were noninferior to biodegradable polymer DES (BP-DES) in terms of patient-oriented composite outcomes at 12 months after percutaneous coronary intervention.
Article
Cardiac & Cardiovascular Systems
Kirstine Norregaard Hansen, Lisette Okkels Jensen, Michael Maeng, Martin Kirk Christensen, Manijeh Noori, Johnny Kahlert, Lars Jakobsen, Anders Junker, Phillip Freeman, Julia Ellert-Gregersen, Bent Raungaard, Christian Juhl Terkelsen, Karsten Tange Veien, Evald Hoj Christiansen
Summary: This study compared the efficacy of biodegradable polymer drug-eluting stents (O-SES) and biodegradable polymer biolimus-eluting stents (N-BES) in percutaneous coronary intervention. The findings showed no significant difference in the 5-year target lesion failure rate between the two stents, but the O-SES had a lower rate of definite stent thrombosis in the first year. However, this difference was not maintained after 5 years.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Tiffany Patterson, Tim Clayton, Matthew Dodd, Zeeshan Khawaja, Marie Claude Morice, Karen Wilson, Won-Keun Kim, Nicolas Meneveau, Rainer Hambrecht, Jonathan Byrne, Didier Carrie, Doug Fraser, David H. Roberts, Sagar N. Doshi, Azfar Zaman, Adrian P. Banning, Helene Eltchaninoff, Herve Le Breton, David Smith, Ian Cox, Derk Frank, Anthony Gershlick, Mark de Belder, Martyn Thomas, David Hildick-Smith, Bernard Prendergast, Simon Redwood
Summary: This study aimed to determine whether PCI prior to TAVR in patients with significant coronary artery disease would produce noninferior clinical results compared to no PCI. The results showed no significant difference in death and rehospitalization rates at 1 year between PCI and no PCI, but the noninferiority margin was not met, and PCI resulted in a higher risk of bleeding.
JACC-CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Sebastiano Gili, Stefano Galli, Giovanni Teruzzi, Giulia Santagostino Baldi, Paolo Ravagnani, Franco Fabbiocchi, Antonio Bartorelli, Piero Montorsi, Daniela Trabattoni
Summary: This study retrospectively analyzed the clinical outcomes and safety of the BP-SES in male and female patients. The results showed that the ultrathin strut BP-SES was a safe and effective option for the treatment of CAD in both men and women, with a very low stent thrombosis rate and favorable long-term outcomes.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
J. J. Coughlan, Lorenz Raber, Salvatore Brugaletta, Sebastian Kufner, Michael Maeng, Lisette Okkels Jensen, Luis Ortega-Paz, Sarah Bar, Karl-Ludwig Laugwitz, Morten Madsen, Dik Heg, Alp Aytekin, Stephan Windecker, Kevin Kris Warnakula Olesen, Manel Sabate, Adnan Kastrati, Salvatore Cassese
Summary: This study analyzed the long-term follow-up outcomes of patients receiving drug-eluting stent (DES) implantation and found that female patients have an increased risk of early myocardial infarction but no difference in cardiovascular mortality compared with male patients. Additionally, female patients require fewer repeat revascularizations during the follow-up period.
Article
Cardiac & Cardiovascular Systems
Jung-Kyu Han, Doyeon Hwang, Seokhun Yang, Sang-Hyeon Park, Jeehoon Kang, Han-Mo Yang, Kyung Woo Park, Hyun-Jae Kang, Bon-Kwon Koo, Seung-Ho Hur, Weon Kim, Seok Yeon Kim, Sang-Hyun Park, Seung Hwan Han, Sang-Hyun Kim, Sanghoon Shin, Yong Hoon Kim, Kyungil Park, Namho Lee, Seung Jin Lee, Jin Won Kim, Hyo-Soo Kim
Summary: This study investigated the efficacy of 3- to 6-month dual antiplatelet therapy (DAPT) compared to 12-month DAPT after percutaneous coronary intervention using third-generation drug-eluting stents. The findings demonstrated that the shorter DAPT duration was noninferior to the longer duration in terms of net adverse clinical events. Further research is needed to generalize these results.
Article
Cardiac & Cardiovascular Systems
Sung-Jin Hong, Byeong-Keuk Kim, Iksung Cho, Hee-Yeol Kim, Seung-Woon Rha, Seung-Hwan Lee, Sang Min Park, Yong Hoon Kim, Hyuk-Jae Chang, Chul-Min Ahn, Young-Guk Ko Md, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang
Summary: The study demonstrates that pre-procedural coronary CTA-guidance for CTO resulted in higher success rates in PCI, with fewer immediate periprocedural complications such as coronary perforations or myocardial infarction. Higher success rates were more prominent in patients with higher J-CTO scores.
JACC-CARDIOVASCULAR IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Xiao Long Lin, Qiu Yu Li, Dong Hui Zhao, Jing Hua Liu, Qian Fan
Summary: This study found that the level of serum glycated albumin (GA) is significantly associated with a high risk of in-stent restenosis (ISR) after drug-eluting stent (DES) implantation in patients with acute coronary syndrome (ACS). Adding GA to a baseline risk model increases the predictive potential for ISR.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Takashi Muramatsu, Shinichiro Masuda, Nozomi Kotoku, Ken Kozuma, Hideyuki Kawashima, Yuki Ishibashi, Gaku Nakazawa, Kuniaki Takahashi, Takayuki Okamura, Yosuke Miyazaki, Hiroki Tateishi, Masato Nakamura, Norihiro Kogame, Taku Asano, Shimpei Nakatani, Yoshihiro Morino, Yuki Katagiri, Kai Ninomiya, Shigetaka Kageyama, Hiroshi Takahashi, Scot Garg, Shengxian Tu, Kengo Tanabe, Yukio Ozaki, Patrick W. Serruys, Yoshinobu Onuma
Summary: This study aimed to evaluate the safety and feasibility of reduced dose prasugrel monotherapy in Japanese patients with chronic coronary syndrome (CCS). Results showed no primary bleeding or ischemic events, or any stent thrombosis during the treatment period.
CIRCULATION JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Daniele Andreini, Edoardo Conte, Saima Mushtaq, Eleonora Melotti, Carlo Gigante, Maria Elisabetta Mancini, Marco Guglielmo, Gerardo Lo Russo, Andrea Baggiano, Andrea Annoni, Alberto Formenti, Alessandra Magini, Gianluca Pontone, Piergiuseppe Agostoni, Antonio L. Bartorelli, Mauro Pepi, Yoshinobu Onuma, Patrick W. Serruys
Summary: This study evaluated the feasibility and diagnostic accuracy of cardiac computed tomography (CCT) compared to cardiac magnetic resonance (CMR) in patients with newly diagnosed left ventricular dysfunction. The results showed high concordance between CCT and CMR in suggesting the cause of dysfunction and assessing myocardial fibrosis. CCT demonstrated high diagnostic accuracy and was confirmed to accurately assess coronary circulation.
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Anantharaman Ramasamy, Ameer Hamid A. Khan, Jackie Cooper, Judit Simon, Pal Maurovich-Horvat, Retesh Bajaj, Pieter Kitslaar, Rajiv Amersey, Ajay Jain, Andrew Deaner, Johan H. C. Reiber, James C. Moon, Jouke Dijkstra, Patrick W. Serruys, Anthony Mathur, Andreas Baumbach, Ryo Torii, Francesca Pugliese, Christos Bourantas
Summary: This study evaluated the application of different coronary computed tomography angiography (CCTA) reconstruction methods in coronary atherosclerosis using intravascular ultrasound as the reference standard. The results showed that CCTA reconstruction with thinner slice thickness, smooth kernel, and highest strength advanced IR enabled more accurate quantification of the lumen and plaque in coronary atherosclerosis. Rating: 8/10
JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY
(2023)
Article
Cardiac & Cardiovascular Systems
Rutao Wang, Mattia Lunardi, Hironori Hara, Chao Gao, Masafumi Ono, Piroze M. Davierwala, David R. Holmes, Friedrich W. Mohr, Nick Curzen, Francesco Burzotta, Robert-Jan van Geuns, Arie Pieter Kappetein, Stuart J. Head, Daniel J. F. M. Thuijs, Ling Tao, Scot Garg, Yoshinobu Onuma, William Wijns, Patrick W. Serruys
Summary: This study investigated the impact of repeat revascularization within 5 years on 10-year mortality in patients with three-vessel and/or left main coronary artery disease after PCI/CABG. The results showed that repeat revascularization within 5 years had no impact on 10-year all-cause death in the overall population. However, among patients requiring repeat procedures, the 10-year mortality was higher after initial treatment with PCI than after CABG.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Laust Dupont Rasmussen, Simon Winther, Salma Raghad Karim, Jelmer Westra, Jane Kirk Johansen, Hanne Maare Sondergaard, Osama Hammid, Emelyne Sevestre, Yoshinobu Onuma, Mette Nyegaard, June Anita Ejlersen, Evald Christiansen, Ashkan Eftekhari, Niels Ramsing Holm, Samuel Emil Schmidt, Morten Bottcher
Summary: Objective Validation studies found that 35%-40% of patients with coronary artery disease have low pretest probability and acoustic detection could potentially improve clinical likelihood stratification. The aims were to investigate the diagnostic performance of an acoustic-based CAD score and study the reclassification potential of a dual likelihood strategy.
Editorial Material
Cardiac & Cardiovascular Systems
Hendrik Wienemann, Hesham Elzomor, Elmar Kuhn, Jan-Malte Sinning, Stephan Baldus, Patrick W. Serruys, Matti Adam
Article
Multidisciplinary Sciences
Eric K. W. Poon, Masafumi Ono, Xinlei Wu, Jouke Dijkstra, Yu Sato, Matthew Kutyna, Ryo Torii, Johan H. C. Reiber, Christos V. Bourantas, Peter Barlis, Mohammed S. El-Kurdi, Martijn Cox, Renu Virmani, Yoshinobu Onuma, Patrick W. Serruys
Summary: This study examined the effect of endothelial shear stress (ESS) on the morphological changes of a biorestorative coronary bypass graft using computational fluid dynamics (CFD) simulation. The results showed that the presence of an endoluminal flap compromised the flow and increased shear stress, potentially leading to tissue fatigue failure. This study provides important insights into the pathophysiology of biorestorative grafts.
SCIENTIFIC REPORTS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Kai Ninomiya, Shigetaka Kageyama, Hiroki Shiomi, Nozomi Kotoku, Shinichiro Masuda, Pruthvi Revaiah, Scot Garg, Neil O'leary, Takeshi Kimura, Yoshinobu Onuma, Patrick Serruys, Patrick Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Pruthvi Chenniganahosahalli Revaiah, Asishkumar Mandalay, Gunasekaran Sengottuvelu, Ahmed Elkoumy, Hesham Elzomor, Mahmoud Abdelshafy, Sanjeev Bhatt, Yoshinobu Onuma, Osama Soliman, Patrick W. Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Pruthvi Chenniganahosahalli Revaiah, Schinichiro Masuda, Shigetaka Kageyama, Kai Ninomiya, Nozomi Kotoku, Bo Wang, He Xingqiang, Yoshinobu Onuma, Patrick W. Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Pruthvi Chenniganahosahalli Revaiah, Bo Wang, Shinichiro Masuda, Kai Ninomiya, Shigetaka Kageyama, Nozomi Kotoku, He Xingqiang, Tsung-Ying Tsai, Yoshinobu Onuma, Adrian Wlodarczak, Shengxian Tu, Patrick W. Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
TsungYing Tsai, Shigetaka Kageyama, Yoshinobu Onuma, Giulio Pompilio, Daniele Andreini, Saima Mushtaq, Gianluca Pontone, Gianluca Pontone, Mark La Meir, Johan De Mey, Kaoru Tanaka, Torsten Doenst, Ulf Teichgraeber, Ulf Teichgraeber, Ulrich Schneider, John Puskas, Jagat Narula, Patrick W. Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Bo Wang, Randall Lee, Yoshinobu Onuma, Patrick W. J. C. Serruys, Ling Tao
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Kai Ninomiya, Shigetaka Kageyama, Hiroki Shiomi, Shinichiro Masuda, Nozomi Kotoku, Pruthvi Revaiah, Scot Garg, Neil O'Leary, Takeshi Kimura, Yoshinobu Onuma, Patrick W. Serruys
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Xinlei Wu, Patrick W. Serruys, Xiaojie Yu, Yuanxue Sun, Yanru Chen, Daozhu Wu, Xinmin Zhang, Lianpin Wu
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)