Mammalian nerve globins in search of functions

Cerebrovascular Pathology and Amyloid Plaque Formation in Alzheimer’s Disease

(2014) Chu-Wan Lee et al.   Current Alzheimer Research

Neuroglobin involvement in visual pathways through the optic nerve

(2013) Christophe Lechauve et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Hemoglobin is present as a canonical α2β2 tetramer in dopaminergic neurons

(2013) Roberta Russo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Non-covalent and covalent modifications modulate the reactivity of monomeric mammalian globins

(2013) Paolo Ascenzi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Expression patterns and adaptive functional diversity of vertebrate myoglobins

(2013) Signe Helbo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Neuroglobin and neuronal cell survival

(2013) Marco Fiocchetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients

(2013) Hong-Wu Xu et al.   BMC CANCER

Neuroglobin Modification by Reactive Quinone Species

(2013) Stefania Nicolis et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Mechanisms of Neuroprotection from Hypoxia-Ischemia (HI) Brain Injury by Up-regulation of Cytoglobin (CYGB) in a Neonatal Rat Model

(2013) Shu-Feng Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice

(2013) Marie Orre et al.   NEUROBIOLOGY OF AGING

Mitochondrial Mechanisms of Neuroglobin’s Neuroprotection

(2013) Zhanyang Yu et al.   Oxidative Medicine and Cellular Longevity

Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration

(2013) S. Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroglobin upregulation induced by 17β-estradiol sequesters cytocrome c in the mitochondria preventing H2O2-induced apoptosis of neuroblastoma cells

(2013) E De Marinis et al.   Cell Death & Disease

Inhibition of the activation of hepatic stellate cells by arundic acid via the induction of cytoglobin

(2012) Wenhao Cui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of the Function of Cytoglobin as an Oxygen-Dependent Regulator of Nitric Oxide Concentration

(2012) Xiaoping Liu et al.   BIOCHEMISTRY

Neuroglobin, a Novel Target for Endogenous Neuroprotection against Stroke and Neurodegenerative Disorders

(2012) Zhanyang Yu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human Neuroglobin Functions as an Oxidative Stress-responsive Sensor for Neuroprotection

(2012) Seiji Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the Mechanism and Magnitude of Cytoglobin-mediated Nitrite Reduction and Nitric Oxide Generation under Anaerobic Conditions

(2012) Haitao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

17β-Oestradiol Anti-Inflammatory Effects in Primary Astrocytes Require Oestrogen Receptor β-Mediated Neuroglobin Up-Regulation

(2012) E. De Marinis et al.   JOURNAL OF NEUROENDOCRINOLOGY

Endothelial cell expression of haemoglobin α regulates nitric oxide signalling

(2012) Adam C. Straub et al.   NATURE

Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain

(2012) Dyna I. Shirasaki et al.   NEURON

Neuroglobin of seals and whales: Evidence for a divergent role in the diving brain

(2012) M. Schneuer et al.   NEUROSCIENCE

Interactions between vascular endothelial growth factor and neuroglobin

(2012) Kunlin Jin et al.   NEUROSCIENCE LETTERS

Hypoxia-inducible factor-1 and neuroglobin expression

(2012) Bryan Haines et al.   NEUROSCIENCE LETTERS

Protection from Intracellular Oxidative Stress by Cytoglobin in Normal and Cancerous Oesophageal Cells

(2012) Fiona E. McRonald et al.   PLoS One

Promotion of Liver and Lung Tumorigenesis in DEN-Treated Cytoglobin-Deficient Mice

(2011) Le Thi Thanh Thuy et al.   AMERICAN JOURNAL OF PATHOLOGY

Cytoglobin, a Novel Member of the Globin Family, Protects Kidney Fibroblasts against Oxidative Stress under Ischemic Conditions

(2011) Hiroshi Nishi et al.   AMERICAN JOURNAL OF PATHOLOGY

Lipid binding to cytoglobin leads to a change in haem co-ordination: a role for cytoglobin in lipid signalling of oxidative stress

(2011) Brandon J. Reeder et al.   BIOCHEMICAL JOURNAL

Analysis of the mitochondrial proteome in multiple sclerosis cortex

(2011) Laurie Broadwater et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cytoglobin: biochemical, functional and clinical perspective of the newest member of the globin family

(2011) Urszula Oleksiewicz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Neuroglobin, estrogens, and neuroprotection

(2011) Elisabetta De Marinis et al.   IUBMB LIFE

Cardiolipin drives cytochrome c proapoptotic and antiapoptotic actions

(2011) Paolo Ascenzi et al.   IUBMB LIFE

14-3-3 Binding and Phosphorylation of Neuroglobin during Hypoxia Modulate Six-to-Five Heme Pocket Coordination and Rate of Nitrite Reduction to Nitric Oxide

(2011) Thottala Jayaraman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Neuroglobin Functions as a Redox-regulated Nitrite Reductase

(2011) Mauro Tiso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circulating IGF1 regulates hippocampal IGF1 levels and brain gene expression during adolescence

(2011) Han Yan et al.   JOURNAL OF ENDOCRINOLOGY

Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling

(2011) Li-Ming Chen et al.   JOURNAL OF NEUROCHEMISTRY

Neuroglobin-prion protein interaction: what's the function?

(2011) Pasquale Palladino et al.   JOURNAL OF PEPTIDE SCIENCE

Species-specific functional evolution of neuroglobin

(2011) Keisuke Wakasugi et al.   Marine Genomics

Identification of neuroglobin-interacting proteins using yeast two-hybrid screening

(2011) Z. Yu et al.   NEUROSCIENCE

17β-Estradiol – A New Modulator of Neuroglobin Levels in Neurons: Role in Neuroprotection against H2O2-Induced Toxicity

(2011) Elisabetta De Marinis et al.   NEUROSIGNALS

Pharmacological Induction of Neuroglobin Expression

(2011) Kunlin Jin et al.   PHARMACOLOGY

Upregulation of Hemoglobin Expression by Oxidative Stress in Hepatocytes and Its Implication in Nonalcoholic Steatohepatitis

(2011) Wensheng Liu et al.   PLoS One

Gene expression profiles and differential cytoglobin expression in atrophy and adenocarcinoma of the prostate

(2011) Ashish P. Mogal et al.   PROSTATE

Cytoglobin Exhibits Anti-Fibrosis Activity on Liver In Vivo and In Vitro

(2011) Xin He et al.   PROTEIN JOURNAL

Knockdown of Cytoglobin Expression Sensitizes Human Glioma Cells to Radiation and Oxidative Stress

(2011) Jingye Fang et al.   RADIATION RESEARCH

Old proteins - new locations: myoglobin, haemoglobin, neuroglobin and cytoglobin in solid tumours and cancer cells

(2010) T. A. Gorr et al.   Acta Physiologica

Alzheimer's disease is associated with lower hemoglobin levels and anemia: The Australian Imaging Biomarker Lifestyle (AIBL) study of aging

(2010) Noel G. Faux et al.   Alzheimers & Dementia

Anatomical characterization of cytoglobin and neuroglobin mRNA and protein expression in the mouse brain

(2010) Christian Ansgar Hundahl et al.   BRAIN RESEARCH

Hypoxic regulation of cytoglobin and neuroglobin expression in human normal and tumor tissues

(2010) Marwan Emara et al.   Cancer Cell International

Estradiol Replacement Alters Expression of Genes Related to Neurotransmission and Immune Surveillance in the Frontal Cortex of Middle-Aged, Ovariectomized Rats

(2010) Miklós Sárvári et al.   ENDOCRINOLOGY

Cytoglobin conformations and disulfide bond formation

(2010) Christophe Lechauve et al.   FEBS Journal

A role for human neuroglobin in apoptosis

(2010) Thomas Brittain et al.   IUBMB LIFE

Myoglobin's old and new clothes: from molecular structure to function in living cells

(2010) G. Gros et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models

(2010) B M Andrus et al.   MOLECULAR PSYCHIATRY

Neuroglobin, cytoglobin, and myoglobin contribute to hypoxia adaptation of the subterranean mole rat Spalax

(2010) A. Avivi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroglobin Expression in Ischemic Stroke

(2010) Kunlin Jin et al.   STROKE

Reduction of ischemic cell death in cultured Islets of Langerhans by the induction of cytoglobin

(2010) John I. Stagner et al.   Islets

Brain Alpha- and Beta-Globin Expression after Intracerebral Hemorrhage

(2010) Yangdong He et al.   Translational Stroke Research

Silencing neuroglobin enhances neuronal vulnerability to oxidative injury by down-regulating 14-3-3γ

(2009) Shi-qiao Ye et al.   ACTA PHARMACOLOGICA SINICA

β-thalassemia Trait as a Protective Factor Against Alzheimer Disease

(2009) Mohammad Kazem Fallahzadeh et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death

(2009) Subhadip Raychaudhuri et al.   APOPTOSIS

Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer

(2009) R J Shaw et al.   BRITISH JOURNAL OF CANCER

Cytoglobin Is Expressed in the Vasculature and Regulates Cell Respiration and Proliferation via Nitric Oxide Dioxygenation

(2009) Katharine E. Halligan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurons express hemoglobin α- and β-chains in rat and human brains

(2009) Franziska Richter et al.   JOURNAL OF COMPARATIVE NEUROLOGY

What is the function of neuroglobin?

(2009) T. Burmester et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Hyaline Protoplasmic Astrocytopathy of Neocortex

(2009) E. Tessa Hedley-Whyte et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Anemia and 9-Year Domain-Specific Cognitive Decline in Community-Dwelling Older Women: The Women's Health and Aging Study II

(2009) Jennifer A. Deal et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Antihypoxic Effects of Neuroglobin in Hypoxia-Preconditioned Mice and SH-SY5Y Cells

(2009) Guo Shao et al.   NEUROSIGNALS

Medulloblastoma with myogenic differentiation showing double immunopositivity for synaptophysin and myoglobin

(2009) Mizue Kido et al.   PATHOLOGY INTERNATIONAL

Unexpected expression of  - and  -globin in mesencephalic dopaminergic neurons and glial cells

(2009) M. Biagioli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Patterns of Distribution of Oxygen-Binding Globins, Neuroglobin and Cytoglobin in Human Retina

(2008) Jelena Ostojić   ARCHIVES OF OPHTHALMOLOGY

Medulloblastoma demonstrating multipotent differentiation: case report

(2008) Hiroyuki Sakata et al.   Brain Tumor Pathology

Structure and function evolution in the superfamily of globins

(2008) Henri Wajcman et al.   COMPTES RENDUS BIOLOGIES

Cytoglobin:A Novel Potential Gene Medicine for Fibrosis and Cancer Therapy

(2008) Yinghui Lv et al.   CURRENT GENE THERAPY

Regulation of hypoxic neuronal death signaling by neuroglobin

(2008) Adil A. Khan et al.   FASEB JOURNAL

Globins and hypoxia adaptation in the goldfish, Carassius auratus

(2008) Anja Roesner et al.   FEBS Journal

A role for neuroglobin: Resetting the trigger level for apoptosis in neuronal and retinal cells

(2008) Angela Fago et al.   IUBMB LIFE

Diversity of Globin Function: Enzymatic, Transport, Storage, and Sensing

(2008) Serge N. Vinogradov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Cerebral Ischemia on Neuronal Hemoglobin

(2008) Yangdong He et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Expression of Hemoglobin in Rodent Neurons

(2008) Dominik W Schelshorn et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Reactions of ferrous neuroglobin and cytoglobin with nitrite under anaerobic conditions

(2008) Morten Gjerning Petersen et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Effects of neuroglobin overexpression on mitochondrial function and oxidative stress following hypoxia/reoxygenation in cultured neurons

(2008) Jianxiang Liu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Hemoglobin Is Expressed by Mesangial Cells and Reduces Oxidant Stress

(2008) H. Nishi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Low dose rotenone treatment causes selective transcriptional activation of cell death related pathways in dopaminergic neurons in vivo

(2008) B.H. Meurers et al.   NEUROBIOLOGY OF DISEASE

Functional Outcomes of Anemia in Older Adults

(2008) Paulo H.M. Chaves   SEMINARS IN HEMATOLOGY

The functional polymorphism of the hemoglobin-binding protein haptoglobin influences susceptibility to idiopathic Parkinson's disease

(2007) Paola Costa-Mallen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Neuroglobin: an endogenous neuroprotectant

(2007) D GREENBERG et al.   CURRENT OPINION IN PHARMACOLOGY

Neuroglobin protects against nitric oxide toxicity

(2007) Kunlin Jin et al.   NEUROSCIENCE LETTERS