Role of energy- and nutrient-sensing kinases AMP-activated Protein Kinase (AMPK) and Mammalian Target of Rapamycin (mTOR) in Adipocyte Differentiation

Regulation of Immune Responses by mTOR

(2012) Jonathan D. Powell et al.   Annual Review of Immunology

DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity

(2012) Mathieu Laplante et al.   Cell Metabolism

Adipose-derived stem cells induced dendritic cells undergo tolerance and inhibit Th1 polarization

(2012) Wei Peng et al.   CELLULAR IMMUNOLOGY

The adipose organ at a glance

(2012) S. Cinti   Disease Models & Mechanisms

GRK2 contribution to the regulation of energy expenditure and brown fat function

(2012) Rocio Vila-Bedmar et al.   FASEB JOURNAL

The role of AMP-activated protein kinase in regulating white adipose tissue metabolism

(2012) R.B. Ceddia   MOLECULAR AND CELLULAR ENDOCRINOLOGY

TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1

(2012) Christian C. Dibble et al.   MOLECULAR CELL

Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK

(2012) Yu-yi Lin et al.   NATURE

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cold tolerance, cold-induced hyperphagia, and nonshivering thermogenesis are normal in α1-AMPK−/− mice

(2011) Jake D. Bauwens et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

(2011) Ken Inoki et al.   Annual Review of Pharmacology and Toxicology

The Ca2+/Calmodulin-Dependent Protein Kinase Kinase, CaMKK2, Inhibits Preadipocyte Differentiation

(2011) Fumin Lin et al.   ENDOCRINOLOGY

Adrenergic Regulation of AMP-activated Protein Kinase in Brown Adipose Tissuein Vivo

(2011) Thomas Pulinilkunnil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by AMP-activated protein kinase

(2011) Eung-Kyun Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

mTOR-rictor is the Ser473 kinase for AKT1 in mouse one-cell stage embryos

(2011) Zhe Zhang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Transcriptional networks and chromatin remodeling controlling adipogenesis

(2011) Rasmus Siersbæk et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A new era for brown adipose tissue: New insights into brown adipocyte function and differentiation*

(2011) Rocio Vila-Bedmar et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation

(2010) G. Barbatelli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

Distribution and Development of Brown Adipocytes in the Murine and Human Adipose Organ

(2010) Andrea Frontini et al.   Cell Metabolism

Tuning mTORC1 Activity for Balanced Self-Renewal and Differentiation

(2010) Larissa S. Carnevalli et al.   DEVELOPMENTAL CELL

Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue

(2010) V. P. Houde et al.   DIABETES

Adenosine 5′-Monophosphate-Activated Protein Kinase-Mammalian Target of Rapamycin Cross Talk Regulates Brown Adipocyte Differentiation

(2010) Rocio Vila-Bedmar et al.   ENDOCRINOLOGY

Regional differences in cellular mechanisms of adipose tissue gain with overfeeding

(2010) Y. D. Tchoukalova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Emerging Role of mTOR in Lipid Biosynthesis

(2009) Mathieu Laplante et al.   CURRENT BIOLOGY

Brown Fat in Humans: Turning up the Heat on Obesity

(2009) P. Seale et al.   DIABETES

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

c-Jun N-Terminal Kinase 1/2 Activation by Tumor Necrosis Factor-α Induces Insulin Resistance In Human Visceral But Not Subcutaneous Adipocytes: Reversal by Liver X Receptor Agonists

(2009) Sonia Fernández-Veledo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypertrophy and/or Hyperplasia: Dynamics of Adipose Tissue Growth

(2009) Junghyo Jo et al.   PLoS Computational Biology

T-lymphocyte Infiltration in Visceral Adipose Tissue

(2008) Ulrich Kintscher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism

(2008) Haiming Cao et al.   CELL

Identification of White Adipocyte Progenitor Cells In Vivo

(2008) Matthew S. Rodeheffer et al.   CELL

Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration

(2008) Pazit Polak et al.   Cell Metabolism

AMP-activated Protein Kinase Is Activated as a Consequence of Lipolysis in the Adipocyte

(2008) Marie-Soleil Gauthier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle

(2008) Eric B. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

(2008) Chong Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Dynamics of fat cell turnover in humans

(2008) Kirsty L. Spalding et al.   NATURE

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE