Mitochondrial protein homeostasis

The MIA pathway: A tight bond between protein transport and oxidative folding in mitochondria

(2012) Diana Stojanovski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism

(2012) Roland Lill et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitofilin complexes: conserved organizers of mitochondrial membrane architecture

(2012) Ralf M. Zerbes et al.   BIOLOGICAL CHEMISTRY

Mitochondrial quality control: a matter of life and death for neurons

(2012) Elena I Rugarli et al.   EMBO JOURNAL

Glutathione redox potential in the mitochondrial intermembrane space is linked to the cytosol and impacts the Mia40 redox state

(2012) Kerstin Kojer et al.   EMBO JOURNAL

Atp23 biogenesis reveals a chaperone-like folding activity of Mia40 in the IMS of mitochondria

(2012) Daniel Weckbecker et al.   EMBO JOURNAL

Oxa1-Ribosome Complexes Coordinate the Assembly of CytochromecOxidase in Mitochondria

(2012) Melanie Keil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mitochondrial Oxidase Assembly Protein1 (Oxa1) Insertase Forms a Membrane Pore in Lipid Bilayers

(2012) Vivien Krüger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes

(2012) Michael Gebert et al.   JOURNAL OF CELL BIOLOGY

Impaired Folding of the Mitochondrial Small TIM Chaperones Induces Clearance by the i-AAA Protease

(2012) Michael J. Baker et al.   JOURNAL OF MOLECULAR BIOLOGY

The inner-mitochondrial distribution of Oxa1 depends on the growth conditions and on the availability of substrates

(2012) Stefan Stoldt et al.   MOLECULAR BIOLOGY OF THE CELL

In vivo evidence for cooperation of Mia40 and Erv1 in the oxidation of mitochondrial proteins

(2012) Lena Böttinger et al.   MOLECULAR BIOLOGY OF THE CELL

Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes

(2012) Katrin Krumpe et al.   MOLECULAR BIOLOGY OF THE CELL

Biogenesis of the preprotein translocase of the outer mitochondrial membrane: protein kinase A phosphorylates the precursor of Tom40 and impairs its import

(2012) Sanjana Rao et al.   MOLECULAR BIOLOGY OF THE CELL

Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria

(2012) Bernadette Schreiner et al.   MOLECULAR BIOLOGY OF THE CELL

Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae

(2012) K. M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial quality control: an integrated network of pathways

(2012) Fabian Fischer et al.   TRENDS IN BIOCHEMICAL SCIENCES

Roles of Dom34:Hbs1 in Nonstop Protein Clearance from Translocators for Normal Organelle Protein Influx

(2012) Toshiaki Izawa et al.   Cell Reports

Processing of mitochondrial presequences

(2011) Dirk Mossmann et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Regulation of Mitochondrial Protein Import by Cytosolic Kinases

(2011) Oliver Schmidt et al.   CELL

Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis

(2011) Karina von der Malsburg et al.   DEVELOPMENTAL CELL

The mitochondrial contact site complex, a determinant of mitochondrial architecture

(2011) Max Harner et al.   EMBO JOURNAL

Lateral release of proteins from the TOM complex into the outer membrane of mitochondria

(2011) Max Harner et al.   EMBO JOURNAL

Presequence-dependent folding ensures MrpL32 processing by them-AAA protease in mitochondria

(2011) Florian Bonn et al.   EMBO JOURNAL

Direct Interaction of Mitochondrial Targeting Presequences with Purified Components of the TIM23 Protein Complex

(2011) Milit Marom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Disulfide Relay: Redox-regulated Protein Import into the Intermembrane Space

(2011) Johannes M. Herrmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

(2011) Suzanne Hoppins et al.   JOURNAL OF CELL BIOLOGY

Tim50’s presequence receptor domain is essential for signal driven transport across the TIM23 complex

(2011) Christian Schulz et al.   JOURNAL OF CELL BIOLOGY

Cbp3–Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochromebsynthesis and assembly

(2011) Steffi Gruschke et al.   JOURNAL OF CELL BIOLOGY

Targeting Capacity and Conservation of PreP Homologues Localization in Mitochondria of Different Species

(2011) Nyosha Alikhani et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis for the Function of Tim50 in the Mitochondrial Presequence Translocase

(2011) Xinguo Qian et al.   JOURNAL OF MOLECULAR BIOLOGY

Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization

(2011) F.-Nora Vögtle et al.   MOLECULAR BIOLOGY OF THE CELL

MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization

(2011) Alwaleed K. Alkhaja et al.   MOLECULAR BIOLOGY OF THE CELL

A Pathway of Protein Translocation in Mitochondria Mediated by the AAA-ATPase Bcs1

(2011) Nikola Wagener et al.   MOLECULAR CELL

Dual Function of Sdh3 in the Respiratory Chain and TIM22 Protein Translocase of the Mitochondrial Inner Membrane

(2011) Natalia Gebert et al.   MOLECULAR CELL

Tail-anchored membrane protein insertion into the endoplasmic reticulum

(2011) Ramanujan S. Hegde et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial protein import: from transport pathways to an integrated network

(2011) Thomas Becker et al.   TRENDS IN BIOCHEMICAL SCIENCES

Oxidative Protein Folding in the Mitochondrial Intermembrane Space

(2010) Dionisia P. Sideris et al.   ANTIOXIDANTS & REDOX SIGNALING

The many faces of the mitochondrial TIM23 complex

(2010) Dejana Mokranjac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Multiple pathways in the integration of proteins into the mitochondrial outer membrane

(2010) Jovana Dukanovic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Ubiquitin–Proteasome System and mitochondria — Reciprocity

(2010) Nurit Livnat-Levanon et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Cooperation of Stop-Transfer and Conservative Sorting Mechanisms in Mitochondrial Protein Transport

(2010) Maria Bohnert et al.   CURRENT BIOLOGY

IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation

(2010) Giovanni Benard et al.   EMBO JOURNAL

Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35

(2010) Christoph Potting et al.   EMBO JOURNAL

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

The mitochondrial UPR - protecting organelle protein homeostasis

(2010) C. M. Haynes et al.   JOURNAL OF CELL SCIENCE

The Matrix Peptide Exporter HAF-1 Signals a Mitochondrial UPR by Activating the Transcription Factor ZC376.7 in C. elegans

(2010) Cole M. Haynes et al.   MOLECULAR CELL

Mitochondrial Disulfide Bond Formation Is Driven by Intersubunit Electron Transfer in Erv1 and Proofread by Glutathione

(2010) Melanie Bien et al.   MOLECULAR CELL

A Stress-Responsive System for Mitochondrial Protein Degradation

(2010) Jin-Mi Heo et al.   MOLECULAR CELL

Mitochondrial protein import: from proteomics to functional mechanisms

(2010) Oliver Schmidt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inventory control: cytochrome c oxidase assembly regulates mitochondrial translation

(2010) David U. Mick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PUF proteins: repression, activation and mRNA localization

(2010) Tara Quenault et al.   TRENDS IN CELL BIOLOGY

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Mitochondrial carrier protein biogenesis: role of the chaperones Hsc70 and Hsp90

(2009) Vincenzo Zara et al.   BIOCHEMICAL JOURNAL

Supramolecular organization of ATP synthase and respiratory chain in mitochondrial membranes

(2009) Ilka Wittig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The organellar peptidasome, PreP: A journey from Arabidopsis to Alzheimer's disease

(2009) Elzbieta Glaser et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Co-translational membrane insertion of mitochondrially encoded proteins

(2009) Martin Ott et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability

(2009) F.-Nora Vögtle et al.   CELL

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy

(2009) Tomotake Kanki et al.   DEVELOPMENTAL CELL

Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy

(2009) Koji Okamoto et al.   DEVELOPMENTAL CELL

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

A novel intermembrane space–targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding

(2009) Dionisia P. Sideris et al.   JOURNAL OF CELL BIOLOGY

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Sue/g

(2009) Regina Rabl et al.   JOURNAL OF CELL BIOLOGY

Two Modular Forms of the Mitochondrial Sorting and Assembly Machinery Are Involved in Biogenesis of α-Helical Outer Membrane Proteins

(2009) Nicolas Thornton et al.   JOURNAL OF MOLECULAR BIOLOGY

Tom20 Mediates Localization of mRNAs to Mitochondria in a Translation-Dependent Manner

(2009) E. Eliyahu et al.   MOLECULAR AND CELLULAR BIOLOGY

Distinct Forms of Mitochondrial TOM-TIM Supercomplexes Define Signal-Dependent States of Preprotein Sorting

(2009) A. Chacinska et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of Tim50 in the Transfer of Precursor Proteins from the Outer to the Inner Membrane of Mitochondria

(2009) Dejana Mokranjac et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of the Signal Directing Tim9 and Tim10 into the Intermembrane Space of Mitochondria

(2009) Dusanka Milenkovic et al.   MOLECULAR BIOLOGY OF THE CELL

MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria

(2009) Lucia Banci et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

Dissecting Membrane Insertion of Mitochondrial β-Barrel Proteins

(2008) Stephan Kutik et al.   CELL

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

(2008) David J. Pagliarini et al.   CELL

Quality control of mitochondria: protection against neurodegeneration and ageing

(2008) Takashi Tatsuta et al.   EMBO JOURNAL

Mitochondrial protein import: precursor oxidation in a ternary complex with disulfide carrier and sulfhydryl oxidase

(2008) Diana Stojanovski et al.   JOURNAL OF CELL BIOLOGY

Integration of tail-anchored proteins into the mitochondrial outer membrane does not require any known import components

(2008) C. Kemper et al.   JOURNAL OF CELL SCIENCE

The Transmembrane Segment of Tom20 Is Recognized by Mim1 for Docking to the Mitochondrial TOM Complex

(2008) Joanne M. Hulett et al.   JOURNAL OF MOLECULAR BIOLOGY

Ubiquitin–Proteasome-dependent Degradation of a Mitofusin, a Critical Regulator of Mitochondrial Fusion

(2008) Mickael M.J. Cohen et al.   MOLECULAR BIOLOGY OF THE CELL

Yeast Mitochondrial Biogenesis: A Role for the PUF RNA-Binding Protein Puf3p in mRNA Localization

(2008) Yann Saint-Georges et al.   PLoS One

Mim1 Functions in an Oligomeric Form to Facilitate the Integration of Tom20 into the Mitochondrial Outer Membrane

(2007) Jelena Popov-Čeleketić et al.   JOURNAL OF MOLECULAR BIOLOGY