Targeted siRNA delivery to diseased microvascular endothelial cells-Cellular and molecular concepts

Targeted Gene Silencing Using RGD-Labeled Chitosan Nanoparticles

(2010) H. D. Han et al.   CLINICAL CANCER RESEARCH

Cancer therapy via modulation of micro RNA levels: a promising future

(2010) Satya K. Kota et al.   DRUG DISCOVERY TODAY

Targeted SAINT-O-Somes for improved intracellular delivery of siRNA and cytotoxic drugs into endothelial cells

(2010) Joanna E. Adrian et al.   JOURNAL OF CONTROLLED RELEASE

The role of carrier size in the pharmacodynamics of antisense and siRNA oligonucleotides

(2010) Leaf Huang et al.   JOURNAL OF DRUG TARGETING

RNA interference for therapy in the vascular endothelium

(2010) Jörg Kaufmann et al.   MICROVASCULAR RESEARCH

Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery (review)

(2010) Ryan B. Huang et al.   MOLECULAR MEMBRANE BIOLOGY

Targeted delivery of RNAi therapeutics for cancer therapy

(2010) Jun Li et al.   Nanomedicine

MicroRNA-132–mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis

(2010) Sudarshan Anand et al.   NATURE MEDICINE

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

(2010) Inge A M de Graaf et al.   Nature Protocols

Targeting microRNAs in cancer: rationale, strategies and challenges

(2010) Ramiro Garzon et al.   NATURE REVIEWS DRUG DISCOVERY

Endothelial activation and circulating markers of endothelial activation in kidney disease

(2010) Ton J. Rabelink et al.   Nature Reviews Nephrology

Heterogeneity in Endothelial Responsiveness to Cytokines, Molecular Causes, and Pharmacological Consequences

(2010) Grietje Molema   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Targeted Delivery of Nucleic Acid-Based Therapeutics to the Pulmonary Circulation

(2009) Ramalinga Kuruba et al.   AAPS Journal

Lipidic Systems for In Vivo siRNA Delivery

(2009) Sherry Y. Wu et al.   AAPS Journal

siRNA vs. shRNA: Similarities and differences

(2009) Donald D. Rao et al.   ADVANCED DRUG DELIVERY REVIEWS

Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers

(2009) Phapanin Charoenphol et al.   BIOMATERIALS

Targeted transfection increases siRNA uptake and gene silencing of primary endothelial cells in vitro — A quantitative study

(2009) Sigridur A. Ásgeirsdóttir et al.   JOURNAL OF CONTROLLED RELEASE

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Non-viral nanosystems for systemic siRNA delivery

(2009) Stephanie David et al.   PHARMACOLOGICAL RESEARCH

Strategies for targeted nonviral delivery of siRNAs in vivo

(2009) Sang-Soo Kim et al.   TRENDS IN MOLECULAR MEDICINE

Regulation of Arterial-Venous Differences in Tumor Necrosis Factor Responsiveness of Endothelial Cells by Anatomic Context

(2008) Meng Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Polymeric particles conjugated with a ligand to VCAM-1 exhibit selective, avid, and focal adhesion to sites of atherosclerosis

(2008) Sudhir P. Deosarkar et al.   BIOTECHNOLOGY AND BIOENGINEERING

Atu027, a Liposomal Small Interfering RNA Formulation Targeting Protein Kinase N3, Inhibits Cancer Progression

(2008) M. Aleku et al.   CANCER RESEARCH

Targeted delivery of therapeutics to endothelium

(2008) Eric Simone et al.   CELL AND TISSUE RESEARCH

Microvascular endothelial cell heterogeneity: general concepts and pharmacological consequences for anti-angiogenic therapy of cancer

(2008) Elise Langenkamp et al.   CELL AND TISSUE RESEARCH

Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes

(2008) D AUGUSTE et al.   JOURNAL OF CONTROLLED RELEASE

Nonviral Methods for siRNA Delivery

(2008) Kun Gao et al.   MOLECULAR PHARMACEUTICS

Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers

(2008) Silvia Muro et al.   MOLECULAR THERAPY

Chemical Modification of siRNAs for In Vivo Use

(2008) Mark A. Behlke   OLIGONUCLEOTIDES

Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles

(2007) Shyh-Dar Li et al.   JOURNAL OF CONTROLLED RELEASE