DNA as a Platform to Program Assemblies with Emerging Functions in Chemical Biology

RTD-1Mimic Containing γPNA Scaffold Exhibits Broad-Spectrum Antibacterial Activities

(2012) Srinivas Rapireddy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoreductive Uncaging of Fluorophore in Response to Protein Oligomers by Templated Reaction in Vitro and in Cellulo

(2012) Kalyan K. Sadhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembled Antibody Multimers through Peptide Nucleic Acid Conjugation

(2012) Stephanie A. Kazane et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oligonucleotide-Templated Reactions for Sensing Nucleic Acids

(2012) Aya Shibata et al.   MOLECULES

Extreme Bendability of DNA Less than 100 Base Pairs Long Revealed by Single-Molecule Cyclization

(2012) R. Vafabakhsh et al.   SCIENCE

Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds

(2012) Ethan A. Englund et al.   Nature Communications

Fluorescence Detection of Intron Lariat RNA with Reduction-Triggered Fluorescent Probes

(2011) Kazuhiro Furukawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA-Triggered Synthesis and Bioactivity of Proapoptotic Peptides

(2011) Anne Erben et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA-Controlled Bivalent Presentation of Ligands for the Estrogen Receptor

(2011) Frank Abendroth et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA as a Molecular Ruler: Interrogation of a Tandem SH2 Domain with Self-Assembled, Bivalent DNA-Peptide Complexes

(2011) Hendrik Eberhard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Improved Templated Fluorogenic Probes Enhance the Analysis of Closely Related Pathogenic Bacteria by Microscopy and Flow Cytometry

(2011) Raphael M. Franzini et al.   BIOCONJUGATE CHEMISTRY

Generating DNA Synbodies from Previously Discovered Peptides

(2011) Rui Liu et al.   CHEMBIOCHEM

Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells

(2011) Mihai Ciobanu et al.   CHEMICAL COMMUNICATIONS

DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker

(2011) Katarzyna Gorska et al.   CHEMICAL COMMUNICATIONS

20 years of DNA-encoded chemical libraries

(2011) Luca Mannocci et al.   CHEMICAL COMMUNICATIONS

Small-molecule discovery from DNA-encoded chemical libraries

(2011) Ralph E. Kleiner et al.   CHEMICAL SOCIETY REVIEWS

Two Successive Reactions on a DNA Template: A Strategy for Improving Background Fluorescence and Specificity in Nucleic Acid Detection

(2011) Raphael M. Franzini et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nucleic Acid-Templated Energy Transfer Leading to a Photorelease Reaction and its Application to a System Displaying a Nonlinear Response

(2011) Manuel Röthlingshöfer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleic Acid Templated Uncaging of Fluorophores Using Ru-Catalyzed Photoreduction with Visible Light

(2011) Manuel Röthlingshöfer et al.   ORGANIC LETTERS

DNA-programmed spatial screening of carbohydrate–lectin interactions

(2011) Christian Scheibe et al.   Chemical Science

DNA-templated combinatorial assembly of small molecule fragments amenable to selection/amplification cycles

(2011) Jean Pierre Daguer et al.   Chemical Science

Rapid fluorescence imaging of miRNAs in human cells using templated Staudinger reaction

(2011) Katarzyna Gorska et al.   Chemical Science

Combinatorial Self-Assembly of Glycan Fragments into Microarrays

(2010) Kuo-Ting Huang et al.   CHEMBIOCHEM

Ligand dimerization programmed by hybridization to study multimeric ligand–receptor interactions

(2010) Katarzyna Gorska et al.   CHEMICAL COMMUNICATIONS

An autocatalytic chromogenic and fluorogenic photochemical reaction controlled by nucleic acids

(2010) Subrata Dutta et al.   CHEMICAL COMMUNICATIONS

Binary Probes for Nucleic Acid Analysis

(2010) Dmitry M. Kolpashchikov   CHEMICAL REVIEWS

DNA-Templated Homo- and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV

(2009) Katarzyna Gorska et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reduction-Triggered Fluorescent Amplification Probe for the Detection of Endogenous RNAs in Living Human Cells

(2009) Kazuhiro Furukawa et al.   BIOCONJUGATE CHEMISTRY

A Nucleic Acid Dependent Chemical Photocatalysis in Live Human Cells

(2009) Dumitru Arian et al.   CHEMISTRY-A EUROPEAN JOURNAL

Creating Protein Affinity Reagents by Combining Peptide Ligands on Synthetic DNA Scaffolds

(2009) Berea A. R. Williams et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imaging of mRNA in Live Cells Using Nucleic Acid-Templated Reduction of Azidorhodamine Probes

(2009) Zbigniew Pianowski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Nucleic Acid Detection by Templated Reductive Quencher Release

(2009) Raphael M. Franzini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembly of a nanoscale DNA box with a controllable lid

(2009) Ebbe S. Andersen et al.   NATURE

Design, synthesis and selection of DNA-encoded small-molecule libraries

(2009) Matthew A Clark et al.   Nature Chemical Biology

Chemical control of biomolecular interaction modules

(2009) Frank Altenbrunn et al.   PURE AND APPLIED CHEMISTRY

Target-Catalyzed Transfer Reactions for the Amplified Detection of RNA

(2008) Tom N. Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Postsynthetic DNA Modification through the Copper-Catalyzed Azide-Alkyne Cycloaddition Reaction

(2008) Philipp M. E. Gramlich et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Reduction-Triggered Fluorescence Probe for Sensing Nucleic Acids

(2008) Hiroshi Abe et al.   BIOCONJUGATE CHEMISTRY

7-Azidomethoxy-Coumarins as Profluorophores for Templated Nucleic Acid Detection

(2008) Raphael M. Franzini et al.   CHEMBIOCHEM

Achieving Turnover in DNA-Templated Reactions

(2008) Tom N. Grossmann et al.   CHEMBIOCHEM

Novel strategies for the site-specific covalent labelling of nucleic acids

(2008) Samuel H. Weisbrod et al.   CHEMICAL COMMUNICATIONS

Nucleic acid encoding to program self-assembly in chemical biology

(2008) Zbigniew L. Pianowski et al.   CHEMICAL SOCIETY REVIEWS

Reduction-triggered red fluorescent probes for dual-color detection of oligonucleotide sequences

(2008) Kazuhiro Furukawa et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A tumor mRNA-triggered photodynamic molecular beacon based on oligonucleotide hairpin control of singlet oxygen production

(2008) Juan Chen et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries

(2008) L. Mannocci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA