Split Inteins: Nature’s Protein Ligases

Photocontrol of Protein Activity Mediated by the Cleavage Reaction of a Split Intein

(2011) Jens Binschik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Control of One-Pot Trans-Splicing Reactions by Using a Wild-Type and Designed Split Intein

(2011) Neel H. Shah et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modification of transmembrane and GPI-anchored proteins on living cells by efficient protein trans-splicing using the Npu DnaE intein

(2011) Tulika Dhar et al.   CHEMICAL COMMUNICATIONS

Evolution of cyclic peptide protease inhibitors

(2011) T. S. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein immobilization on liposomes and lipid-coated nanoparticles by protein trans-splicing

(2010) Nam Ky Chu et al.   JOURNAL OF PEPTIDE SCIENCE

Protein trans-splicing and its use in structural biology: opportunities and limitations

(2010) Gerrit Volkmann et al.   Molecular BioSystems

Segmental isotopic labeling of multi-domain and fusion proteins by protein trans-splicing in vivo and in vitro

(2010) Mikko Muona et al.   Nature Protocols

Segmental Isotopic Labeling of a Central Domain in a Multidomain Protein by ProteinTrans-Splicing Using Only One Robust DnaE Intein

(2009) Alena E. L. Busche et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Split Inteins as Versatile Tools for Protein Semisynthesis

(2009) Henning D. Mootz   CHEMBIOCHEM

Solution structure of DnaE intein fromNostoc punctiforme: Structural basis for the design of a new split intein suitable for site-specific chemical modification

(2009) Jesper S. Oeemig et al.   FEBS LETTERS

The naturally splitNpuDnaE intein exhibits an extraordinarily high rate in the proteintrans-splicing reaction

(2009) Joachim Zettler et al.   FEBS LETTERS

Novel Split Intein fortrans-Splicing Synthetic Peptide onto C Terminus of Protein

(2009) Julia H. Appleby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid selection of cyclic peptides that reduce α-synuclein toxicity in yeast and animal models

(2009) Joshua A Kritzer et al.   Nature Chemical Biology

Fractured genes: a novel genomic arrangement involving new split inteins and a new homing endonuclease family

(2009) Bareket Dassa et al.   NUCLEIC ACIDS RESEARCH

In Vivo and In Vitro Protein Ligation by Naturally Occurring and Engineered Split DnaE Inteins

(2009) A. Sesilja Aranko et al.   PLoS One

Traceless protein splicing utilizing evolved split inteins

(2009) S. W. Lockless et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of intein activity by its neighboring extein substrates

(2009) G. Amitai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of HIV Budding by a Genetically Selected Cyclic Peptide Targeting the Gag−TSG101 Interaction

(2008) Ali Tavassoli et al.   ACS Chemical Biology

Activation of Protein Splicing by Protease- or Light-Triggered O to N Acyl Migration

(2008) Miquel Vila-Perelló et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total chemical synthesis of proteins

(2008) Stephen B. H. Kent   CHEMICAL SOCIETY REVIEWS

Protein Trans-Splicing as a Means for Viral Vector-Mediated In Vivo Gene Therapy

(2008) Juan Li et al.   HUMAN GENE THERAPY

Interaction Studies and Alanine Scanning Analysis of a Semi-synthetic Split Intein Reveal Thiazoline Ring Formation from an Intermediate of the Protein Splicing Reaction

(2008) Christina Ludwig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An efficient on-column expressed protein ligation strategy: Application to segmental triple labeling of human apolipoprotein E3

(2008) Wentao Zhao et al.   PROTEIN SCIENCE

Genetic Selection of Cyclic Peptide Dam Methyltransferase Inhibitors

(2007) Todd A. Naumann et al.   CHEMBIOCHEM