Article
Multidisciplinary Sciences
Thomas Puiseux, Anou Sewonu, Ramiro Moreno, Simon Mendez, Franck Nicoud
Summary: A numerical approach for simulating time-resolved 3D phase-contrast MRI under realistic flow conditions is presented. The Navier-Stokes and Bloch equations are solved with specific strategies to reduce computational cost. The simulated results compare favorably with experimental data.
Article
Radiology, Nuclear Medicine & Medical Imaging
Alexis Ollitrault, Frederique Charbonneau, Marie-Laure Herdan, Olivier Berges, Kevin Zuber, Lama Giovansili, Pauline Launay, Julien Savatovsky, Augustin Lecler
Summary: This study concluded that compared to a conventional MRI protocol, a single Dixon-T2WI sequence showed higher sensitivity and specificity, fewer artifacts, and increased confidence when assessing thyroid eye disease.
EUROPEAN RADIOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Cristina Lento, Derek J. Wilson
Summary: Life at the molecular level is a dynamic world, and subsecond time-resolved mass spectrometry provides a unique window into the dynamic behavior of biological macromolecules. This technique has made important contributions to understanding the functional and pathological processes of biomolecules.
Article
Radiology, Nuclear Medicine & Medical Imaging
Martin Georg Zeilinger, Karl-Philipp Kunze, Camila Munoz, Radhouene Neji, Michaela Schmidt, Pierre Croisille, Rafael Heiss, Wolfgang Wuest, Michael Uder, Rene Michael Botnar, Christoph Treutlein, Claudia Prieto
Summary: The efficacy of an in-line non-rigid motion-compensated reconstruction (NRC) in an image-navigated high-resolution three-dimensional late gadolinium enhancement (LGE) sequence with Dixon water-fat separation was investigated in a clinical setting. The study found that NRC outperformed translational motion-compensated reconstructions (TC) in overall image quality, contrast ratios, and LGE quantification. The sharper depictions of LGE in NRC may lead to more accurate measurements.
EUROPEAN RADIOLOGY
(2022)
Article
Engineering, Electrical & Electronic
Max H. C. van Riel, Tristan van Leeuwen, Cornelis A. T. van den Berg, Alessandro Sbrizzi
Summary: This study presents an extended Spectro-Dynamic MRI framework that can reconstruct time-resolved MR images and dynamical parameters at a high temporal resolution. The proposed method, solved by an iterative algorithm, outperforms the traditional two-step approach. Experimental results show that this method can accurately reconstruct all dynamic variables under different sampling patterns.
IEEE TRANSACTIONS ON COMPUTATIONAL IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Rodrigo de Castro Luna, Neil M. Kumar, Jan Fritz, Shivani Ahlawat, Laura M. Fayad
Summary: This study demonstrates that a 4-fold accelerated 3D T2-weighted CAIPIRINHA SPACE TSE sequence is equivalent to conventional 2DT2 TSE sequence for evaluating soft tissue tumor characteristics. The 3DT2 MRI offers higher spatial resolution and shorter acquisition times compared to 2DT2 MRI, making it interchangeable in tumor protocols.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Martin Georg Zeilinger, Marco Wiesmueller, Christoph Forman, Michaela Schmidt, Camila Munoz, Davide Piccini, Karl-Philipp Kunze, Radhouene Neji, Rene Michael Botnar, Claudia Prieto, Michael Uder, Matthias May, Wolfgang Wuest
Summary: The 3D LGE sequence provides comparable LGE detection compared to 2D imaging and appears to be superior in evaluating the extent of pericardial involvement in patients suspected with pericarditis due to the robust Dixon fat suppression. However, the scan duration for 3D imaging was significantly longer, but good or excellent fat suppression was achieved in the majority of cases.
EUROPEAN RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Sebastian Weingaertner, Oemer B. Demirel, Francisco Gama, Iain Pierce, Thomas A. Treibel, Jeanette Schulz-Menger, Mehmet Akcakaya
Summary: This study proposes a method to obtain phase-resolved late gadolinium enhancement (LGE) images using cardiac magnetic resonance imaging. The method involves three steps and has been evaluated in phantom imaging, healthy subjects, and patients. The results demonstrate reliable imaging in the phantom and healthy subjects, while the imaging resolution and noise resilience in patients are lower compared to the reference technique. The proposed technique shows potential in integrating the advantages of phase-resolved cardiac magnetic resonance with LGE imaging, but further improvements are needed for clinical use.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Benjamin Henninger, Michaela Plaikner, Heinz Zoller, Andre Viveiros, Stephan Kannengiesser, Werner Jaschke, Christian Kremser
Summary: This study evaluated the feasibility of using a 3D-multiecho-Dixon sequence and its improved version for MR quantification of hepatic iron, showing both sequences to be reliable and comparable to established relaxometry methods.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Felicia Wright, Malte Warncke, Martin Sinn, Inka Ristow, Alexander Lenz, Christoph Riedel, Bjoern P. Schoennagel, Shuo Zhang, Michael G. Kaul, Gerhard Adam, Yskert von Kodolitsch, Susanne Sehner, Peter Bannas
Summary: This study compared the accuracy and precision of 3D-Dixon and 2D-SSFP MR imaging for assessing aortic diameter in Marfan patients. The results showed that both respiratory-gated 3D-Dixon and breath-hold 2D-SSFP MR imaging provided accurate and precise measurements of aortic diameter. However, 3D-Dixon imaging had fewer imaging artifacts and the advantage of orthogonal multiplanar reformations of the aortic root, making it recommended for monitoring aortic diameter in Marfan patients.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Filip Klimes, Andreas Voskrebenzev, Marcel Gutberlet, Arnd J. Obert, Gesa H. Poehler, Robert Grimm, Lea Behrendt, Cristian Crisosto, Julian Glandorf, Tawfik Moher Alsady, Frank Wacker, Jens Vogel-Claussen
Summary: The study evaluated the repeatability of 3D PREFUL MRI parameters and compared them with pulmonary functional lung testing (PFT) in healthy subjects and COPD patients. The results showed good repeatability of some parameters and moderate repeatability of others, with correlations found between 3D PREFUL and PFT measures.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Multidisciplinary Sciences
Hsueh-Ying Chen, C. Blake Wilson, Robert Tycko
Summary: The spatial resolution of MRI is limited by signal detection sensitivity, but can be improved by performing measurements at low temperature and using dynamic nuclear polarization (DNP) technique. This allows for higher resolution and shorter data acquisition times, offering a promising direction for high-resolution MRI studies.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xueyin Liao, Xiaoqi Wang, Zhentan Xu, Shiwei Guo, Congmin Gu, Zhengyu Jin, Tong Su, Yu Chen, Huadan Xue, Mingyong Yang
Summary: This study suggests that using T1W fat-only images produced by Dixon MRI is an effective method for identifying grafted fat and quantifying postoperative changes. The signal contrast and retention rate decrease gradually after surgery.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Seitaro Oda, Kosuke Morita, Masafumi Kidoh, Yasunori Nagayama, Takeshi Nakaura, Yuichiro Shirahama, Yuta Tsurusaki, Kenichi Matsushita, Kenichi Tsujita, Toshinori Hirai
Summary: Additional digital content can be found in the text.
CIRCULATION-CARDIOVASCULAR IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Pinzhen Chen, Zhou Zhou, Li Sun, Xueke Yu, Kai Li, Jin Li, Min He, Xiaoyue Zhou, Fei Luo, Jun Zhao, Wei Chen
Summary: This study investigated the sex differences in age-related back extensor muscle degeneration using Dixon MRI and analyzed the relationship between quantitative muscle parameters and back muscle strength in healthy adults. The results showed that the fat fraction of multifidus muscle and erector spinae significantly increased with age in both genders. In females, the total erector spinae functional cross-sectional area and relative functional cross-sectional area correlated with age. In males, all muscle size parameters, except total multifidus muscle cross-sectional area, correlated with age. Back extension muscle strength correlated with muscle fat fraction, cross-sectional area, and functional cross-sectional area. The study concluded that functional cross-sectional area had the highest association with back muscle strength compared to fat fraction and cross-sectional area.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marius Vach, Julian A. Luetkens, Anton Faron, Alexander Isaak, Babak Salam, Daniel Thomas, Ulrike Attenberger, Alois M. Sprinkart
Summary: This study aimed to investigate whether total volume of epicardial (ECF) and pericardial fat (PCF) can be estimated by axial single-slice measurements and in a four-chamber view. The results showed strong correlations between axial single-slice measurements and total fat volumes, with the best correlation found at the level of the left coronary artery. The correlations between single-slice measurements in the four-chamber view and total fat volumes were lower. This time-efficient analysis allows for studies of larger patient cohorts and the opportunist determination of ECF/PCF from routine examinations.
Review
Radiology, Nuclear Medicine & Medical Imaging
Judith Herrmann, Daniel Wessling, Dominik Nickel, Simon Arberet, Haidara Almansour, Carmen Afat, Saif Afat, Sebastian Gassenmaier, Ahmed E. Othman
Summary: This study evaluated the clinical performance of a deep learning-accelerated single-breath-hold half-Fourier acquisition single-shot turbo spin echo (HASTEDL)-sequence for T2-weighted fat-suppressed MRI of the abdomen at 1.5 T and 3 T, compared to the standard T2-weighted fatsuppressed multi-shot turbo spin echo-sequence. HASTEDL showed excellent image quality, good diagnostic confidence, and lesion detection capability, with a significant reduction in acquisition time compared to the standard sequence.
ACADEMIC RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Haidara Almansour, Judith Herrmann, Sebastian Gassenmaier, Andreas Lingg, Marcel Dominik Nickel, Stephan Kannengiesser, Simon Arberet, Ahmed E. Othman, Saif Afat
Summary: The study aimed to investigate the impact of a deep learning-based super-resolution reconstruction algorithm on acquisition time and image quality for abdominal MRI. The results showed that the algorithm reduced breath-hold time, improved image sharpness and lesion conspicuity, without compromising image quality or diagnostic confidence.
ACADEMIC RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Fumihito Ichinohe, Kazuki Oyama, Akira Yamada, Hayato Hayashihara, Yasuo Adachi, Yoshihiro Kitoh, Yusuke Kanki, Katsuya Maruyama, Marcel Dominik Nickel, Yasunari Fujinaga
Summary: The usefulness of breath-hold turbo spin echo with deep learning-based reconstruction (BH-DL-TSE) in acquiring fat-suppressed T2-weighted images (FS-T2WI) of the liver was evaluated and compared with conventional free-breathing turbo spin echo (FB-TSE) and breath-hold half Fourier single-shot turbo spin echo with deep learning-based reconstruction (BH-DL-HASTE). BH-DL-TSE provides shorter acquisition time and comparable or better image quality than FB-TSE. BH-DL-TSE and BH-DL-HASTE have their own advantages and may be used complementarily.
INVESTIGATIVE RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tianwen Xie, Tingting Jiang, Qiufeng Zhao, Caixia Fu, Marcel Dominik Nickel, Weijun Peng, Yajia Gu
Summary: In this study, the relationship between model-free and model-based parameters of CDTV DCE-MRI and the clinicopathologic factors and molecular subtypes of IDC was compared. The results showed that model-based parameters had better performance in differentiating different types of breast cancer compared to clinicopathologic factors and molecular subtypes.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Angela Tong, Barun Bagga, Robert Petrocelli, Paul Smereka, Abhinav Vij, Kun Qian, Robert Grimm, Ali Kamen, Mahesh B. Keerthivasan, Marcel Dominik Nickel, Heinrich von Busch, Hersh Chandarana
Summary: This study compared conventional bpMRI with bpMRI including deep learning-accelerated T2WI in diagnosing prostate cancer. The results showed that deep learning-accelerated T2WI can be used to reduce scan time for bpMRI.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Alexander Isaak, Johannes Chang, Narine Mesropyan, Dmitrij Kravchenko, Christoph Endler, Leon Bischoff, Nina Boehling, Claus C. Pieper, Daniel Kuetting, Christian P. Strassburg, Ulrike Attenberger, Christian Jansen, Michael Praktiknjo, Julian A. Luetkens
Summary: This MRI study aimed to evaluate the presence of subclinical myocardial dysfunction, oedema, and fibrosis in non-cirrhotic portal hypertension (NCPH). The results showed that NCPH participants had similar levels of myocardial fibrosis and oedema as compensated cirrhosis, and these abnormalities were associated with splenic markers of portal hypertension.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Orthopedics
Geojeong Seo, Sun Joo Lee, Dae Hyun Park, Sung Hwa Paeng, Gregor Koerzdoerfer, Marcel Dominik Nickel, Jaekon Sung
Summary: The objective of this study was to compare the subjective image quality and lesion detectability of deep learning-accelerated Dixon (DL-Dixon) imaging with routine Dixon imaging of the cervical spine. Results showed that DL-Dixon imaging reduced acquisition time by 23.76% compared to routine Dixon imaging and provided better visibility of anatomical structures. There were no significant differences in lesion detectability between the two imaging methods.
SKELETAL RADIOLOGY
(2023)
Article
Health Care Sciences & Services
Jannik Claus, Neeraj Upadhyay, Angelika Maurer, Julian Klein, Lukas Scheef, Marcel Daamen, Jason Anthony Martin, Ruediger Stirnberg, Alexander Radbruch, Ulrike Attenberger, Tony Stoecker, Henning Boecker
Summary: This study aimed to investigate the effects of regular physical activity (PA) on the functional connectivity (FC) topographies of subregions of the orbitofrontal cortex (OFC). The results showed that PA can induce changes in the FC of OFC subregions. The posterior-lateral right OFC showed decreased FC with the left dorsolateral prefrontal cortex, while the anterior-lateral right OFC showed increased FC with the right middle frontal gyrus. The posterior-lateral left OFC exhibited differential changes in FC with the left postcentral gyrus and the right occipital gyrus. These findings provide clues for further research.
Article
Biochemistry & Molecular Biology
Lea C. Kaminski, Julia Wagenpfeil, Jens Buermann, Philipp L. Lutz, Julian A. Luetkens, Ulrike I. Attenberger, Christian P. Strassburg, Jorg C. Kalff, Hans H. Schild, Claus C. Pieper
Summary: The aim of this study was to retrospectively evaluate the long-term results of lymphatic interventions in adults with abdomino-thoracic lymphatic pathologies. The study found that lymph-vessel embolization (LVE) has a high clinical success rate for treating abdomino-thoracic chylous effusions and can significantly prolong patient survival.
Article
Radiology, Nuclear Medicine & Medical Imaging
Sebastian Nowak, Helen Schneider, Yannik C. Layer, Maike Theis, David Biesner, Wolfgang Block, Benjamin Wulff, Ulrike I. Attenberger, Rafet Sifa, Alois M. Sprinkart
EUROPEAN RADIOLOGY
(2023)
Article
Pediatrics
Sebastian Rassmann, Alexandra Keller, Kyra Skaf, Alexander Hustinx, Ruth Gausche, Miguel A. Ibarra-Arrelano, Tzung-Chien Hsieh, Yolande E. D. Madajieu, Markus M. Noethen, Roland Pfaeffle, Ulrike I. Attenberger, Mark Born, Klaus Mohnike, Peter M. Krawitz, Behnam Javanmardi
Summary: This study presents Deeplasia, a deep-learning approach specifically validated for bone age assessment in patients with skeletal dysplasias. The results show that Deeplasia is competent in assessing bone age and monitoring development in both normal and dysplastic bones.
PEDIATRIC RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Wei Mao, Xiaoqiang Ding, Yuqin Ding, Bohong Cao, Caixia Fu, Bernd Kuehn, Thomas Benkert, Robert Grimm, Dominik Nickel, Jianjun Zhou, Mengsu Zeng
Summary: This study investigated the diagnostic value of functional MRI in assessing renal interstitial fibrosis in patients with chronic kidney disease (CKD). The results showed that functional MRI parameters were strongly correlated with interstitial fibrosis of CKD, suggesting that it could be a powerful noninvasive tool for evaluating CKD interstitial fibrosis.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Luke A. Ginocchio, Paul N. Smereka, Angela Tong, Vinay Prabhu, Dominik Nickel, Simon Arberet, Hersh Chandarana, Krishna P. Shanbhogue
Summary: This study compared a novel single-shot T2-weighted MRI with deep-learning-based image reconstruction to the standard T2-FS sequence for liver MRI. The results showed that the novel sequence had superior image quality in terms of sharpness, motion artifacts, overall image quality, and sharpness of liver lesions, while being acquired in less time than the standard sequence.
ABDOMINAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sebastian Nowak, Andreas Henkel, Maike Theis, Julian Luetkens, Sergej Geiger, Alois M. Sprinkart, Claus C. Pieper, Ulrike Attenberger
Summary: A deep learning pipeline using MR imaging data for assessing shape, volume, and asymmetry of the lower extremities in patients with lipedema or lymphedema is proposed. The pipeline includes localization of anatomical landmarks and quality-assured tissue segmentation. The results show excellent performance in landmark detection and segmentation, allowing for standardized analysis of tissue volume and distribution.
EUROPEAN RADIOLOGY
(2023)