Proteasome inhibitor MG132 induces selective apoptosis in glioblastoma cells through inhibition of PI3K/Akt and NFkappaB pathways, mitochondrial dysfunction, and activation of p38-JNK1/2 signaling

Bortezomib: A New Pro-Apoptotic Agent in Cancer Treatment

(2010) A. Russo et al.   CURRENT CANCER DRUG TARGETS

Current and emerging molecular targets in glioma

(2010) Rafael Roesler et al.   Expert Review of Anticancer Therapy

Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma

(2010) Surasak Phuphanich et al.   JOURNAL OF NEURO-ONCOLOGY

The NFκB-mediated control of RS and JNK signaling in vitamin A-treated cells: Duration of JNK–AP-1 pathway activation may determine cell death or proliferation

(2009) Alfeu Zanotto-Filho et al.   BIOCHEMICAL PHARMACOLOGY

Targeted Therapies for Malignant Glioma

(2009) Ronald W. Mercer et al.   BIODRUGS

The pharmacological NFκB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation

(2009) Alfeu Zanotto-Filho et al.   CANCER LETTERS

SC68896, a Novel Small Molecule Proteasome Inhibitor, Exerts Antiglioma Activity In vitro and In vivo

(2009) P. Roth et al.   CLINICAL CANCER RESEARCH

A survey of glioblastoma genomic amplifications and deletions

(2009) Shailaja K. Rao et al.   JOURNAL OF NEURO-ONCOLOGY

Bortezomib suppresses focal adhesion kinase expression via interrupting nuclear factor-kappa B

(2009) Bor-Sheng Ko et al.   LIFE SCIENCES

z-Leucinyl-Leucinyl-Norleucinal Induces Apoptosis of Human Glioblastoma Tumor-Initiating Cells by Proteasome Inhibition and Mitotic Arrest Response

(2009) M. Monticone et al.   MOLECULAR CANCER RESEARCH

Characterization of caspase-dependent and caspase-independent deaths in glioblastoma cells treated with inhibitors of the ubiquitin-proteasome system

(2009) C. Foti et al.   MOLECULAR CANCER THERAPEUTICS

Identification of Survival Genes in Human Glioblastoma Cells by Small Interfering RNA Screening

(2009) N. G. Thaker et al.   MOLECULAR PHARMACOLOGY

Glioblastoma Subclasses Can Be Defined by Activity among Signal Transduction Pathways and Associated Genomic Alterations

(2009) Cameron Brennan et al.   PLoS One

Bortezomib arrests the proliferation of hepatocellular carcinoma cells HepG2 and JHH6 by differentially affecting E2F1, p21 and p27 levels

(2008) Daniele Baiz et al.   BIOCHIMIE

Phosphatidylinositol 3-Kinase Inhibition Broadly Sensitizes Glioblastoma Cells to Death Receptor- and Drug-Induced Apoptosis

(2008) D. Opel et al.   CANCER RESEARCH

Brazilian marine sponge Polymastia janeirensis induces apoptotic cell death in human U138MG glioma cell line, but not in a normal cell culture

(2008) Mario Luiz Conte da Frota et al.   INVESTIGATIONAL NEW DRUGS

Proteasome Inhibitor-Induced Apoptosis of Glioma Cells Involves the Processing of Multiple Caspases and Cytochrome c Release

(2003) Bettina Wagenknecht et al.   JOURNAL OF NEUROCHEMISTRY