Irinotecan and DNA-PKcs inhibitors synergize in killing of colon cancer cells

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Optimal Delivery of Cytotoxic Chemotherapy for Colon Cancer

(2010) Laura Raftery et al.   CANCER JOURNAL

DNA damage signaling in response to double-strand breaks during mitosis

(2010) Simona Giunta et al.   JOURNAL OF CELL BIOLOGY

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

(2010) Mary Ellen Moynahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ATM- and ATR-mediated response to DNA damage induced by a novel camptothecin, ST1968

(2009) Valentina Zuco et al.   CANCER LETTERS

DNA-PKcs and ATM co-regulate DNA double-strand break repair

(2009) Meena Shrivastav et al.   DNA REPAIR

Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells

(2009) Nozomi Tomimatsu et al.   EMBO REPORTS

Targeted Therapy for Advanced Colorectal Cancer — More Is Not Always Better

(2009) Robert J. Mayer   NEW ENGLAND JOURNAL OF MEDICINE

Chemotherapy, Bevacizumab, and Cetuximab in Metastatic Colorectal Cancer

(2009) Jolien Tol et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tissue-specific DNA-PK-dependent H2AX phosphorylation and γ-H2AX elimination after X-irradiation in vivo

(2008) Manabu Koike et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxaliplatin activity in selected and unselected human ovarian and colorectal cancer cell lines

(2008) Paul Noordhuis et al.   BIOCHEMICAL PHARMACOLOGY

DNA-PK suppresses a p53-independent apoptotic response to DNA damage

(2008) Kay E Gurley et al.   EMBO REPORTS

Impaired NHEJ function in multiple myeloma

(2008) Clara Yang et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks

(2008) W. Y. Mansour et al.   NUCLEIC ACIDS RESEARCH