The Duality of Fgl2 - Secreted Immune Checkpoint Regulator Versus Membrane-Associated Procoagulant: Therapeutic Potential and Implications

Cancer-induced immunosuppressive cascades and their reversal by molecular-targeted therapy

(2013) Yutaka Kawakami et al.   Annals of the New York Academy of Sciences

Dendritic Cell–Based Immunotherapy in Prevention and Treatment of Renal Cell Carcinoma

(2013) Frédéric D. Birkhäuser et al.   JOURNAL OF IMMUNOTHERAPY

Expression of B and T lymphocyte attenuator (BTLA) in macrophages contributes to the fulminant hepatitis caused by murine hepatitis virus strain-3

(2012) Chengying Yang et al.   GUT

Fgl2 Prothrombinase is involved in Severe Acute Pancreatitis-Associated Liver Injury

(2012) Tanzhou Chen et al.   HEPATO-GASTROENTEROLOGY

Intrahepatic Expression of Programmed Death-1 and its Ligands in Patients with HBV-Related Acute-on-Chronic Liver Failure

(2012) Dayan Cao et al.   INFLAMMATION

Characterization of fibrinogen-like protein 2 (FGL2): Monomeric FGL2 has enhanced immunosuppressive activity in comparison to oligomeric FGL2

(2012) Hao Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Downregulation of FGL2/prothrombinase delays HCCLM6 xenograft tumour growth and decreases tumour angiogenesis

(2012) Yanling Liu et al.   LIVER INTERNATIONAL

Thrombosis and cancer

(2012) Annie Young et al.   Nature Reviews Clinical Oncology

FGL2/Fibroleukin mediates hepatic reperfusion injury by induction of sinusoidal endothelial cell and hepatocyte apoptosis in mice

(2011) Nazia Selzner et al.   JOURNAL OF HEPATOLOGY

Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance

(2011) Lin Xie et al.   LIVER TRANSPLANTATION

Programmed Death (PD)-1-Deficient Mice Are Extremely Sensitive to Murine Hepatitis Virus Strain-3 (MHV-3) Infection

(2011) Yongwen Chen et al.   PLoS Pathogens

The FGL2/fibroleukin prothrombinase is involved in alveolar macrophage activation in COPD through the MAPK pathway

(2010) Yanling Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dual Interference with Novel Genes mfgl2 and mTNFR1 Ameliorates Murine Hepatitis Virus Type 3-Induced Fulminant Hepatitis in BALB/cJ Mice

(2010) Sui Gao et al.   HUMAN GENE THERAPY

The novel immunoregulatory molecule FGL2: A potential biomarker for severity of chronic hepatitis C virus infection

(2010) Katharina Foerster et al.   JOURNAL OF HEPATOLOGY

Microarray Analysis of Lymphatic Tissue Reveals Stage-Specific, Gene Expression Signatures in HIV-1 Infection

(2009) Q. Li et al.   JOURNAL OF IMMUNOLOGY

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

The FGL2-FcγRIIB pathway: A novel mechanism leading to immunosuppression

(2008) Hao Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The novel CD4+CD25+ regulatory T cell effector molecule fibrinogen-like protein 2 contributes to the outcome of murine fulminant viral hepatitis

(2008) Itay Shalev et al.   HEPATOLOGY

The Nucleocapsid Protein of SARS-CoV Induces Transcription of hfgl2 Prothrombinase Gene Dependent on C/EBP Alpha

(2008) M. Han et al.   JOURNAL OF BIOCHEMISTRY

Hepatitis B Virus-inducedhFGL2Transcription Is Dependent on c-Ets-2 and MAPK Signal Pathway

(2008) Meifang Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibrinogen-like protein 2/fibroleukin prothrombinase contributes to tumor hypercoagulability via IL-2 and IFN-γ

(2008) Kai Su et al.   WORLD JOURNAL OF GASTROENTEROLOGY