Design of CD40 Agonists and Their Use in Growing B Cells for Cancer Immunotherapy

CD40-Activated B Cells Can Efficiently Prime Antigen-Specific Naïve CD8+ T Cells to Generate Effector but Not Memory T cells

(2012) Mélissa Mathieu et al.   PLoS One

Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand

(2011) A. Jain et al.   BLOOD

Maturation and function of human dendritic cells are regulated by B lymphocytes

(2011) A. Morva et al.   BLOOD

Tumor-Evoked Regulatory B Cells Promote Breast Cancer Metastasis by Converting Resting CD4+ T Cells to T-Regulatory Cells

(2011) P. B. Olkhanud et al.   CANCER RESEARCH

Activated T cells induce rapid CD83 expression on B cells by engagement of CD40

(2011) Birte Kretschmer et al.   IMMUNOLOGY LETTERS

Interaction with Fc RIIB Is Critical for the Agonistic Activity of Anti-CD40 Monoclonal Antibody

(2011) A. L. White et al.   JOURNAL OF IMMUNOLOGY

CD40-Activated B Cell Cancer Vaccine Improves Second Clinical Remission and Survival in Privately Owned Dogs with Non-Hodgkin's Lymphoma

(2011) Karin U. Sorenmo et al.   PLoS One

B regulatory cells and the tumor-promoting actions of TNF-  during squamous carcinogenesis

(2011) T. Schioppa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Adjuvant Effects of Antibodies

(2011) M. J. Smyth et al.   SCIENCE

Soluble CD40 ligand-activated human peripheral B cells as surrogated antigen presenting cells: A preliminary approach for anti-HBV immunotherapy

(2011) Chao Wu et al.   Virology Journal

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Selective Targeting of B Cells with Agonistic Anti-CD40 Is an Efficacious Strategy for the Generation of Induced Regulatory T2-Like B Cells and for the Suppression of Lupus in MRL/lpr Mice

(2009) P. A. Blair et al.   JOURNAL OF IMMUNOLOGY

Using CD40-activated B Cells to Efficiently Identify Epitopes of Tumor Antigens

(2009) Eisei Kondo et al.   JOURNAL OF IMMUNOTHERAPY

CD40-activated B cells can be generated in high number and purity in cancer patients: analysis of immunogenicity and homing potential

(2008) E. Kondo et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CD40 Ligand-activated, antigen-specific B cells are comparable to mature dendritic cells in presenting protein antigens and major histocompatibility complex class I- and class II-binding peptides

(2008) Tahamtan Ahmadi et al.   IMMUNOLOGY

A soluble hexameric form of CD40 ligand activates human dendritic cells and augments memory T cell response

(2008) Isabelle Miconnet et al.   VACCINE

The ‘short’ history of regulatory B cells

(2007) Claudia Mauri et al.   TRENDS IN IMMUNOLOGY