Paclitaxel Induces Acute Pain via Directly Activating Toll like Receptor 4

Interleukin-1 beta enhances endocytosis of glial glutamate transporters in the spinal dorsal horn through activating protein kinase C

(2014) Xisheng Yan et al.   GLIA

Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain

(2013) Susannah S. Lewis et al.   BRAIN BEHAVIOR AND IMMUNITY

Pharmacological validation of a refined burrowing paradigm for prediction of analgesic efficacy in a rat model of sub-chronic knee joint inflammation

(2013) K. Rutten et al.   EUROPEAN JOURNAL OF PAIN

Endogenous Interleukin-1β in Neuropathic Rats Enhances Glutamate Release from the Primary Afferents in the Spinal Dorsal Horn through Coupling with PresynapticN-Methyl-d-aspartic Acid Receptors

(2013) Xisheng Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Astrocytic group I mGluR-dependent potentiation of astrocytic glutamate and potassium uptake

(2013) Prakash Devaraju et al.   JOURNAL OF NEUROPHYSIOLOGY

Stage-dependent anti-allodynic effects of intrathecal Toll-like receptor 4 antagonists in a rat model of cancer induced bone pain

(2013) Xiu Li et al.   Journal of Physiological Sciences

Endogenous activation of presynaptic NMDA receptors enhances glutamate release from the primary afferents in the spinal dorsal horn in a rat model of neuropathic pain

(2013) Xisheng Yan et al.   JOURNAL OF PHYSIOLOGY-LONDON

A rapid analytical method for the quantification of paclitaxel in rat plasma and brain tissue by high-performance liquid chromatography and tandem mass spectrometry

(2013) Pei Li et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Further data supporting that paclitaxel-associated acute pain syndrome is associated with development of peripheral neuropathy

(2012) Brandi N. Reeves et al.   CANCER

High-resolution in vivo imaging of microglia using a versatile nongenetically encoded marker

(2012) Bernd Schwendele et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain

(2012) Fei-xiang Wu et al.   International Journal of Medical Sciences

Targeting the Overproduction of Peroxynitrite for the Prevention and Reversal of Paclitaxel-Induced Neuropathic Pain

(2012) T. Doyle et al.   JOURNAL OF NEUROSCIENCE

The Maintenance of Cisplatin- and Paclitaxel-Induced Mechanical and Cold Allodynia is Suppressed by Cannabinoid CB2 Receptor Activation and Independent of CXCR4 Signaling in Models of Chemotherapy-Induced Peripheral Neuropathy

(2012) Liting Deng et al.   Molecular Pain

Minocycline blocks lipopolysaccharide induced hyperalgesia by suppression of microglia but not astrocytes

(2012) S.-Y. Yoon et al.   NEUROSCIENCE

Nucleus basalis-enabled stimulus-specific plasticity in the visual cortex is mediated by astrocytes

(2012) N. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spontaneous burrowing behaviour in the rat is reduced by peripheral nerve injury or inflammation associated pain

(2011) N. Andrews et al.   EUROPEAN JOURNAL OF PAIN

Dysregulated Src upregulation of NMDA receptor activity: a common link in chronic pain and schizophrenia

(2011) Michael W. Salter et al.   FEBS Journal

Natural History of Paclitaxel-Associated Acute Pain Syndrome: Prospective Cohort Study NCCTG N08C1

(2011) Charles L. Loprinzi et al.   JOURNAL OF CLINICAL ONCOLOGY

Resolving TRPV1- and TNF- -Mediated Spinal Cord Synaptic Plasticity and Inflammatory Pain with Neuroprotectin D1

(2011) C.-K. Park et al.   JOURNAL OF NEUROSCIENCE

Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

(2011) R. E. Sorge et al.   JOURNAL OF NEUROSCIENCE

Involvement of Substance P in Peripheral Neuropathy Induced by Paclitaxel but Not Oxaliplatin

(2011) Y. Tatsushima et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A simple procedure for estimation of total body surface area and determination of a new value of Meeh's constant in rats

(2011) E Gouma et al.   LABORATORY ANIMALS

Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis

(2011) Christina A. Christianson et al.   PAIN

Spinal glial TLR4-mediated nociception and production of prostaglandin E2 and TNF

(2010) O Saito et al.   BRITISH JOURNAL OF PHARMACOLOGY

Impaired Glial Glutamate Uptake Induces Extrasynaptic Glutamate Spillover in the Spinal Sensory Synapses of Neuropathic Rats

(2010) Hui Nie et al.   JOURNAL OF NEUROPHYSIOLOGY

Interactions between the immune and nervous systems in pain

(2010) Ke Ren et al.   NATURE MEDICINE

Minocycline prevents impaired glial glutamate uptake in the spinal sensory synapses of neuropathic rats

(2010) H. Nie et al.   NEUROSCIENCE

Role of TLR4 for paclitaxel chemotherapy in human epithelial ovarian cancer cells

(2009) A. C. Wang et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Glutamate Transporters Prevent Excessive Activation of NMDA Receptors and Extrasynaptic Glutamate Spillover in the Spinal Dorsal Horn

(2009) Hui Nie et al.   JOURNAL OF NEUROPHYSIOLOGY

Synaptically Evoked Glutamate Transporter Currents in Spinal Dorsal Horn Astrocytes

(2009) Haijun Zhang et al.   Molecular Pain

Neuron–glia crosstalk gets serious: role in pain hypersensitivity

(2008) Ke Ren et al.   Current Opinion in Anesthesiology

Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype

(2008) Irmgard Tegeder et al.   EUROPEAN JOURNAL OF PAIN

Glial TLR4 receptor as new target to treat neuropathic pain: Efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice

(2008) Isabella Bettoni et al.   GLIA

Pathological and protective roles of glia in chronic pain

(2008) Erin D. Milligan et al.   NATURE REVIEWS NEUROSCIENCE