Article
Green & Sustainable Science & Technology
Ramisa Shafqat, Dora Marinova, Shahed Khan
Summary: This paper investigates the sustainability potential of intangible cultural heritage preserved in informal settlements, considering them as an extension of rurality in urban areas. The study analyzes two informal settlements in Islamabad, Pakistan, and identifies four themes that constitute sustainability heritage. The research stresses the importance of supporting the cultural heritage of these settlements and finding culturally specific solutions to improve the livability of the city.
Article
Health Care Sciences & Services
Rachel McCauley, Karen Ryan, Regina McQuillan, Geraldine Foley
Summary: Reciprocal support among patients and informal caregivers in palliative care plays a significant role in decision making. Caregivers who feel obligated to care have difficulty communicating and participating in patient care decisions. Caregivers who choose to provide care are more involved in decision making. Open communication between patients and caregivers can help build trust.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2023)
Article
Microbiology
Alice Raffetin, Aude Barquin, Steve Nguala, Giulia Paoletti, Christian Rabaud, Olivier Chassany, Pauline Caraux-Paz, Sarah Covasso, Henri Partouche
Summary: The study found that patients with Lyme disease may experience nonspecific symptoms for several months after treatment, leading to different perceptions and experiences of their disease and care paths. Patients undergo long and challenging care paths, negative impact on health, and express a strong desire for self-management and change.
Article
Gerontology
Klara Raiber, Ellen Verbakel, Alice de Boer
Summary: Informal care, an increasingly important topic in social science research, has received more attention due to the rising pressure of providing care within one's own social network. The Informal Care Model has been tested and found to be effective in understanding the intrapersonal changes in care provision during the COVID-19 lockdown in the Netherlands, providing empirical support for the theoretical model.
EUROPEAN JOURNAL OF AGEING
(2022)
Article
Geriatrics & Gerontology
Nina Lindelof, Ingeborg Nilsson, Hakan Littbrand, Yngve Gustafson, Birgitta Olofsson, Anncristine Fjellman-Wiklund
Summary: The staff team perceived that by working in comprehensive teams they could provide individualized rehabilitation in creative collaboration with the participants through interaction, knowledge exchange, time and continuity, coordination and flexibility, and a holistic view. Challenges to overcome were the involvement of the person with dementia in goal setting and the mediating role of the staff team members. The staff pointed out that by refinement they could achieve well-functioning, competence-enhancing and timesaving teamwork.
Article
Public, Environmental & Occupational Health
Michael Bergmann, Melanie Wagner
Summary: This study analyzed the impact of COVID-19 and related control measures on caregivers and care recipients in Europe and Israel, finding that caregivers experienced increased mental health strains while some care recipients had difficulty accessing adequate care. The perception of unmet care needs was significantly associated with differences in stay-at-home orders across countries.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Ludmila Fleitas Alfonzo, Ankur Singh, George Disney, Tania King
Summary: Young carers, individuals aged 25 years or less who provide unpaid informal care to their family or friends, face negative impacts on their mental health. This study examined gender differences in the mental health effects of informal care among Australian adolescents. The findings indicate that informal care is associated with poorer mental health among boys and girls, with girls experiencing the highest levels of distress. Although the mental health effects are stronger for girls, the difference in mental health disparities between girls and boys is small and uncertain.
SSM-POPULATION HEALTH
(2023)
Article
Nursing
Mona Ahlberg, Carina Bertero, Susanna Agren
Summary: The aim of this study was to understand the family functioning of families with a previously critically ill family member who stayed at the intensive care unit during the pandemic. The findings revealed core categories of value considerateness, anxiety and insecurity in life, and insight into the unpredictability of life, which played a crucial role in helping the families cope with changes in life.
INTENSIVE AND CRITICAL CARE NURSING
(2023)
Article
Public, Environmental & Occupational Health
Christopher Poppe, Martine Verwey, Tenzin Wangmo
Summary: Informal caregivers, mainly family members and friends, play a crucial role in providing supportive and palliative care for people with ALS. The theoretical understanding of ALS informal caregiving work emphasizes on the core category of 'holding the balance', which highlights the importance of ensuring care and normalcy for patients even as the disease progresses towards the end of life. This study accounts for the heterogeneity of ALS progression and takes into consideration various caregiving trajectories influenced by contextual factors.
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2022)
Article
Health Care Sciences & Services
Siyu Zhou, Kai Li, Astushi Ogihara, Xiaohe Wang
Summary: This study investigated the perceptions of traditional Chinese medicine doctors about wearable devices and diagnostic instruments, and explored the factors that influenced their perceptions. The results categorized their perceptions under convenience, reliability, suitable population, machine usage scenario, and the integration of traditional Chinese medicine and information communication technology. The perceptions were found to be influenced by age, title, type of hospital, and specialty. The study concluded that the use of wearable devices and traditional Chinese medicine diagnostic instruments has been gradually accepted by traditional Chinese medicine doctors, but further improvement in knowledge and skills related to information communication technology integration is needed.
Article
Nursing
Mir Hossein Aghaei, Zohreh Vanaki, Eesa Mohammadi
Summary: This qualitative study aimed to explore the meaning of care in providing palliative care to Iranian cancer patients and develop a theory to explain the phenomenon. The results highlighted the importance of reducing patient affliction and anxiety, and promoting psycho-emotional recovery as critical strategies in palliative care provision.
Article
Nursing
Linda Ljungholm, Charlotte Klinga, Anette Edin-Liljegren, Mirjam Ekstedt
Summary: The study aimed to describe essential aspects of care continuity for individuals with complex care needs and their family carers. A conceptual model of care continuity was constructed, with time and space as the core category. The experiences of patients and family carers were closely related to timely personalised care delivery, requiring clarity in responsibilities and roles, interprofessional collaboration, and the development of trusting relationships.
JOURNAL OF CLINICAL NURSING
(2022)
Article
Management
Jayasaegaran Sithambaram, Mohd Hairul Nizam Bin Md Nasir, Rodina Ahmad
Summary: This study identified 38 unique issues and challenges faced by industry practitioners in agile projects, categorized into Organization, People, Process, and Technical factors. Proposed mitigation methods have been mapped into a framework to guide the management of agile-hybrid projects, with a focus on areas such as executive support, alignment with business objectives, understanding of agile principles, teamwork, and skillset of project stakeholders.
INTERNATIONAL JOURNAL OF PROJECT MANAGEMENT
(2021)
Article
Oncology
Dana M. Chase, Jordan Neighbors, Jessica Perhanidis, Bradley J. Monk
Summary: This study found that approximately 25% of ovarian cancer patients had gastrointestinal disorders in the year before diagnosis, and these patients were more likely to receive neoadjuvant chemotherapy, suggesting more advanced disease.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Family Studies
Emmy Tiderington, Emily Bosk, Alicia Mendez
Summary: This study examined how frontline providers adapt and apply the Housing First model to families involved in child welfare. The findings show that providers are modifying the model to address the needs of this population, but there are questions about the fidelity of Housing First when used with families involved in child welfare.
CHILD ABUSE & NEGLECT
(2021)
Article
Clinical Neurology
Katrina Moore, Rhian Convery, Martina Bocchetta, Mollie Neason, David M. Cash, Caroline Greaves, Lucy L. Russell, Mica T. M. Clarke, Georgia Peakman, John van Swieten, Lize Jiskoot, Fermin Moreno, Myriam Barandiaran, Raquel Sanchez-Valle, Barbara Borroni, Robert Laforce, Marie-Claire Dore, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Daniela Galimberti, James B. Rowe, Elizabeth Finger, Matthis Synofzik, Hans-Otto Karnath, Rik Vandenberghe, Alexandre de Mendonca, Carolina Maruta, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Chris Butler, Alex Gerhard, Johannes Levin, Adrian Danek, Markus Otto, Jason D. Warren, Jonathan D. Rohrer, Martin N. Rossor, Nick C. Fox, Ione O. C. Woollacott, Rachelle Shafei, Carolin Heller, Rita Guerreiro, Jose Bras, David L. Thomas, Jennifer Nicholas, Simon Mead, Lieke Meeter, Jessica Panman, Janne Papma, Rick van Minkelen, Yolande Pijnenburg, Begona Indakoetxea, Alazne Gabilondo, Mikel Tainta, Maria de Arriba, Ana Gorostidi, Miren Zulaica, Jorge Villanua, Zigor Diaz, Sergi Borrego-Ecija, Jaume Olives, Albert Llado, Mircea Balasa, Anna Antonell, Nuria Bargallo, Enrico Premi, Maura Cosseddu, Stefano Gazzina, Alessandro Padovani, Roberto Gasparotti, Silvana Archetti, Sandra Black, Sara Mitchell, Ekaterina Rogaeva, Morris Freedman, Ron Keren, David Tang-Wa, Linn Oijerstedt, Christin Andersson, Vesna Jelic, Hakan Thonberg, Andrea Arighi, Chiara Fenoglio, Elio Scarpini, Giorgio Fumagalli, Thomas Cope, Carolyn Timberlake, Timothy Rittman, Christen Shoesmith, Robart Bartha, Rosa Rademakers, Carlo Wilke, Benjamin Bender, Rose Bruffaerts, Philip Van Damme, Mathieu Vandenbulcke, Catarina B. Ferreira, Gabriel Miltenberger, Ana Verdelho, Sonia Afonso, Ricardo Taipa, Paola Caroppo, Giuseppe Di Fede, Giorgio Giaccone, Sara Prioni, Veronica Redaelli, Giacomina Rossi, Pietro Tiraboschi, Diana Duro, Maria Rosario Almeida, Miguel Castelo-Branco, Maria Joao Leitao, Miguel Tabuas-Pereira, Beatriz Santiago, Serge Gauthier, Pedro Rosa-Neto, Michele Veldsman, Toby Flanagan, Catharina Prix, Tobias Hoegen, Elisabeth Wlasich, Sandra Loosli, Sonja Schonecker, Elisa Semler, Sarah Anderl-Straub
Summary: This study investigates semantic cognition in patients with genetic frontotemporal dementia (FTD). The study finds that symptomatic patients scored lower than controls on semantic knowledge, while only late-stage MAPT and C9orf72 mutation carriers scored lower than controls in the presymptomatic groups. Furthermore, the study shows a correlation between mCCT score and brain volume in different regions in different mutation groups.
APPLIED NEUROPSYCHOLOGY-ADULT
(2022)
Article
Clinical Neurology
Marta Scarioni, Priya Gami-Patel, Carel F. W. Peeters, Florianne de Koning, Harro Seelaar, Merel O. Mol, John C. van Swieten, Netherlands Brain Bank, Annemieke J. M. Rozemuller, Jeroen J. M. Hoozemans, Yolande A. L. Pijnenburg, Anke A. Dijkstra
Summary: The majority of patients with frontotemporal dementia have additional pathologies alongside the main pathology. Neuropsychiatric symptoms in FTD are associated with subcortical pathology in the hippocampus, with hallucinations linked to a higher burden of TDP-43 pathology in the granular layer. Different pathological proteins accumulate in various brain regions and contribute to the diverse clinical presentation of frontotemporal lobar degeneration (FTLD).
Article
Clinical Neurology
Emma L. van der Ende, Esther E. Bron, Jackie M. Poos, Lize C. Jiskoot, Jessica L. Panman, Janne M. Papma, Lieke H. Meeter, Elise G. P. Dopper, Carlo Wilke, Matthis Synofzik, Carolin Heller, Imogen J. Swift, Aitana Sogorb-Esteve, Arabella Bouzigues, Barbara Borroni, Raquel Sanchez-Valle, Fermin Moreno, Caroline Graff, Robert Laforce, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, Rik Vandenberghe, James B. Rowe, Alexandre de Mendonca, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Christopher R. Butler, Alexander Gerhard, Johannes Levin, Adrian Danek, Markus Otto, Yolande A. L. Pijnenburg, Sandro Sorbi, Henrik Zetterberg, Wiro J. Niessen, Jonathan D. Rohrer, Stefan Klein, John C. van Swieten, Vikram Venkatraghavan, Harro Seelaar
Summary: This study aimed to model the sequence of biomarker abnormalities in genetic frontotemporal dementia and determine the disease stages of patients. The results showed that NPTX2 and neurofilament light chain were the earliest biomarkers to change. This model could help select suitable patients for pharmaceutical trials and improve patient stratification and tracking of therapeutic interventions.
Article
Geriatrics & Gerontology
Dennis van de Veen, Christian Bakker, Kirsten Peetoom, Yolande Pijnenburg, Janne Papma, Marjolein de Vugt, Raymond Koopmans
Summary: This study aims to reach consensus on the terminology and operational definition of dementia at a young age through a classical Delphi technique. The survey results show that there is consensus on some statements, but further discussion is needed for some details. Therefore, it is recommended to organize an in person consensus meeting to address these issues.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2022)
Article
Geriatrics & Gerontology
Talitha Vrijmoeth, Annelies Wassenaar, Raymond T. C. M. Koopmans, Minke S. Nieuwboer, Marieke Perry
Summary: To achieve successful generalist-specialist collaboration, it is important to clarify roles and expectations, build trust and familiarity, ensure regular communication, and have support from government, payers, and organizations.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Geriatrics & Gerontology
Christian Bakker, Marjon Verboom, Raymond Koopmans
Summary: Although dementia has a profound impact in general, young-onset dementia requires specific care and support. The establishment of an appropriate infrastructure, care centers, and training programs, as well as the development of care standards and quality hallmarks, have improved postdiagnostic care and support for young-onset dementia in the Netherlands.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Editorial Material
Geriatrics & Gerontology
Raymond T. C. M. Koopmans, Bas Leerink, Dederieke A. M. Festen
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Multidisciplinary Sciences
Grace Wei, Janine Diehl-Schmid, Jordi A. Matias-Guiu, Yolande Pijnenburg, Ramon Landin-Romero, Hans Bogaardt, Olivier Piguet, Fiona Kumfor
Summary: The COVID-19 pandemic and its restrictions have negatively affected dementia patients and their caregivers, worsening neuropsychiatric symptoms in patients and causing mental health decline and increased stress in caregivers.
SCIENTIFIC REPORTS
(2022)
Review
Clinical Neurology
Stevie Hendriks, Kirsten Peetoom, Christian Bakker, Raymond Koopmans, Wiesje van der Flier, Janne Papma, Frans Verhey, Marjolein de Vugt, Sebastian Kohler
Summary: Reliable data on the incidence rates for young-onset dementia are lacking, but this study provides the current best estimate. The global age-standardized incidence rate for the age group of 30 to 64 is 11 per 100,000, with 370,000 new cases occurring annually.
ALZHEIMERS & DEMENTIA
(2023)
Review
Psychology, Clinical
Jan Van den Stock, Maxime Bertoux, Janine Diehl-Schmid, Olivier Piguet, Katherine P. Rankin, Florence Pasquier, Simon Ducharme, Yolande Pijnenburg, Fiona Kumfor
Summary: Dodich et al. reviewed the clinical use of social cognition assessment in behavioral variant frontotemporal dementia and proposed an initiative to address the limitations in their study.
NEUROPSYCHOLOGY REVIEW
(2023)
Article
Endocrinology & Metabolism
Fiona Heeman, Denise Visser, Maqsood Yaqub, Sander Verfaillie, Tessa Timmers, Yolande A. L. Pijnenburg, Wiesje M. van der Flier, Bart N. M. van Berckel, Ronald Boellaard, Adriaan A. Lammertsma, Sandeep S. Golla
Summary: Alzheimer's disease is characterized by reduced cerebral blood flow. This study compared the precision of different methods for measuring cerebral blood flow and found that relative blood flow methods had better repeatability than absolute blood flow methods. The high precision of relative blood flow may be due to a compensatory effect of the extraction fraction.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2023)
Article
Geriatrics & Gerontology
Jay L. P. Fieldhouse, Gaby Van Dijk, Freek Gillissen, Marie-Paule E. Van Engelen, Sterre C. M. De Boer, Annemiek Dols, Hendrik-Jan Van Der Waal, Barbara J. Regeer, Everard G. B. Vijverberg, Yolande A. L. Pijnenburg
Summary: This study provides insights from caregivers of behavioural variant frontotemporal dementia (bvFTD) patients regarding the symptoms and their relevance in different disease stages. The findings highlight the importance of considering individual characteristics and early stage interventions.
Article
Geriatrics & Gerontology
Gerrie van Voorden, Raymond T. C. M. Koopmans, Martin Smalbrugge, Sytse U. Zuidema, Anne M. A. van den Brink, Anke Persoon, Richard Oude C. Voshaar, Debby L. Gerritsen
Summary: This study identified successful treatment of persons with dementia and severe challenging behavior, focusing on the well-being of all people involved. Multidisciplinary analysis and treatment as well as the attitudes and skills of those involved are essential to achieving successful treatment outcomes.
AGING & MENTAL HEALTH
(2023)
Article
Neurosciences
Stevie Hendriks, Kirsten Peetoom, Huibert Tange, Janne Papma, Wiesje M. van der Flier, Raymond Koopmans, Christian Bakker, Sebastian Kohler, Marjolein de Vugt
Summary: This study investigated the healthcare use of 75 persons with young-onset dementia (YOD) and identified factors influencing care use. The main reason for general practitioners (GPs) to refer for diagnosis was concerns of caregivers. After diagnosis, a majority of persons received care services, such as case management, day care, and admission to a long-term care facility. However, the presence of a case manager was associated with a lower rate of admission to a long-term care facility. Reasons for not initiating care included reluctance of the persons with YOD or their caregivers, patient death, or lack of GP referral. In conclusion, care use varied among persons with YOD due to different needs and factors, suggesting room for improvement in the care system.
JOURNAL OF ALZHEIMERS DISEASE
(2023)
Article
Clinical Neurology
Aniek M. van Gils, Hanneke F. M. Rhodius-Meester, Anna E. Leeuwis, Dede Handgraaf, Christian Bakker, Kirsten Peetoom, Femke H. Bouwman, Yolande A. L. Pijnenburg, Janne M. Papma, Tanja-Anne Hoogendoorn, Niki Schoonenboom, Astrid van Strien, Nicolaas A. Verwey, Sebastian Kohler, Marjolein E. de Vugt, Wiesje M. van der Flier
Summary: The PRECODE-GP aims to establish a national database of patients with young-onset dementia (YOD) in the Netherlands to gain insight into the occurrence and characteristics of these patients. Initial data from the database showed that the majority of patients were diagnosed with dementia due to Alzheimer's disease, with patients diagnosed with Frontotemporal lobe dementia being the youngest.
ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING
(2023)