Review
Orthopedics
Ahmed Siddiqi, Antonia F. Chen, Nicolas S. Piuzzi, Michael A. Kelly
Summary: The burden of revision total knee arthroplasty (rTKA) is expected to increase due to the rising number of TKA procedures. Managing bone loss during rTKA is challenging, and metaphyseal cones and sleeves have become a popular choice for addressing bone loss. Understanding the available cones and sleeves commercially and when to use them is crucial for preoperative evaluation and planning.
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
(2021)
Article
Orthopedics
Mark J. Heidenreich, Brent A. Lanting, Richard W. McCalden, Douglas D. Naudie, James L. Howard, Steven J. MacDonald, Edward M. Vasarhelyi
Summary: Metaphyseal cones and sleeves offer equally durable survivorship in revision TKA, with periprosthetic joint infection being the most common mode of implant failure.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Joseph Serino, Robert A. Burnett, Anthony J. Boniello, JaeWon Yang, Scott M. Sporer, Craig J. Della Valle
Summary: This study evaluates the cost-effectiveness of tibial cones in revision total knee arthroplasty and finds that they may be cost-effective at lower prices, in younger patients, or in high-risk patients.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Ilan Small, Michael Meghpara, Jonah Stein, Graham S. Goh, Samik Banerjee, P. Maxwell Courtney
Summary: This study compared the survivorship and aseptic revision rates of metaphyseal cones and sleeves at intermediate follow-up. The results showed that there were no significant differences in survivorship over a one-year, two-year, and five-year follow-up when comparing tibial and femoral sleeves to cones directly. Both sleeves and cones performed well at an intermediate-term follow-up.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Malte Ohlmeier, Christian Lausmann, Matthias Wolff, Hussein Abdelaziz, Thorsten Gehrke, Mustafa Citak
Summary: This study analyzed the initial clinical results of calcium-phosphate-coated tibia cones and found a good functional outcome in patients. Further research should focus on long-term clinical and radiological follow-up.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2021)
Article
Biotechnology & Applied Microbiology
Yunong Ao, Lin Guo, Hao Chen, Rui He, Pengfei Yang, Dejie Fu, Lingchuan Gu, Yang Peng, Ran Xiong, Liu Yang, Fuyou Wang
Summary: This study explores the application of 3D-printed personalized porous tantalum cones for reconstructing bone defects in TKA revision. The results show that these cones effectively reconstruct bone defects and improve knee function. Further research is needed to confirm their long-term effectiveness.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Orthopedics
Ittai Shichman, Christian Oakley, Jore H. Willems, Gijs G. van Hellemondt, Petra Heesterbeek, Joshua Rozell, Scott Marwin, Ran Schwarzkopf
Summary: This study examines the mid-term functional and radiographic outcomes in patients undergoing complex revision total knee arthroplasty with a novel metaphyseal cone system. The results show that excellent results can be achieved regardless of the stem fixation technique used.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2022)
Article
Orthopedics
Omar A. Behery, Elaine Z. Shing, Ziqing Yu, Bryan D. Springer, Thomas K. Fehring, Jesse E. Otero
Summary: The study evaluated the survivorship and radiographic outcomes of using metaphyseal cones with short cemented stems in revision total knee arthroplasty. The results showed excellent outcomes without the need for long-stem fixation, avoiding potential complications.
JOURNAL OF ARTHROPLASTY
(2022)
Review
Orthopedics
Ryan P. Roach, Andrew J. Clair, Omar A. Behery, Savyasachi C. Thakkar, Richard Iorio, Ajit J. Deshmukh
Summary: A systematic review comparing porous-coated metaphyseal sleeves and tantalum cones in revision total knee arthroplasty found similar rates of aseptic loosening between the two implants, but nearly double the reoperation rate in TKAs utilizing tantalum cones. More research is needed to fully understand the effectiveness of different implants in revision TKAs.
JOURNAL OF KNEE SURGERY
(2021)
Article
Orthopedics
Yang Li, Xinguang Wang, Hua Tian
Summary: This study retrospectively reviewed the clinical outcomes of using patient-customized three-dimensional printed highly porous metaphyseal cones for reconstructing massive proximal tibial bone defects in revision total knee arthroplasty (RTKA). The results showed favorable clinical and radiological outcomes in terms of improving patient's function and alignment.
ORTHOPAEDIC SURGERY
(2022)
Article
Orthopedics
Ethan A. Remily, Iciar M. Davila Castrodad, Nequesha S. Mohamed, Wayne A. Wilkie, Margaret N. Kelemen, Ronald E. Delanois
Summary: Recent study evaluated the use of 3D-printed titanium metaphyseal cones for managing severe bone loss in revision total knee arthroplasty (rTKA). The results showed well-fixed components with high functional outcomes and implant survivorship rates. Metaphyseal cones may be a viable option for patients with large bone defects during rTKA.
Article
Orthopedics
Alex J. Anatone, Daniel A. Driscoll, Dimitrios A. Flevas, Elexis C. Baral, Brian P. Chalmers, Peter K. Sculco
Summary: This study found significant cement extrusion around the porous surface of metaphyseal cones in revision total knee arthroplasty. Optimizing the cone-bone interface may reduce the risk of cement extrusion and potentially reduce the risk of aseptic loosening.
Article
Orthopedics
Ivan De Martino, Fabio Mancino, Vincenzo Di Matteo, Alessandro Singlitico, Giulio Maccauro, Giorgio Gasparini
Summary: The purpose of this study was to determine the minimum 10-year results of tantalum cones in revision total knee arthroplasty (TKA). The study found that metaphyseal fixation with tantalum cones demonstrated excellent survivorship and fixation at a minimum follow-up of 10 years, with no evidence of implant loosening or migration. This type of metaphyseal reconstruction can be a durable option for patients with massive bone defects.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Michael Eder-Halbedl, Andrea Fink, Martin Pietsch, Oliver Djahani, Siegfried Hofmann
Summary: This study aimed to investigate the survival of first-generation tantalum metal cones (TMC) in revision total knee arthroplasty (RTKA) and evaluate their clinical and radiographic outcomes. The results showed that TMC provides a reliable fixation for severe bone defects and achieves excellent clinical and radiographic outcomes.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Orthopedics
Christopher N. Carender, Qiang An, Matthew W. Tetreault, Ayushmita De, Timothy S. Brown, Nicholas A. Bedard
Summary: The utilization of cementless metaphyseal fixation in revision total knee arthroplasty has increased over time, with tibial metaphyseal cones being the most commonly used implants.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Oncology
Thea Hovgaard Ladegaard, Celine Lykke Sorensen, Rasmus Nielsen, Anders Troelsen, Dhergam Ahmed Ali Al-Mousawi, Rikke Bielefeldt, Michael Mork Petersen, Michala Skovlund Sorensen
Summary: This study examines a large population of patients surgically treated for bone metastases in the appendicular skeleton (aBM) and investigates changes in surgery incidence, differences between patients at different centers, and the value of tumor biopsies and follow-up imaging. The findings suggest no change in surgery incidence and significant differences between patients at different centers.
Article
Rehabilitation
Linda Fernandes, Allan Villadsen, Christina Enciso Holm, Michala Skovlund Sorensen, Mette Kreutzfeldt Zebis, Lars Louis Andersen, Michael Mork Petersen
Summary: The aim of this study was to evaluate work ability, activity limitations and physical activity in adults who had undergone major bone sarcoma resection and reconstruction surgery. The results showed that, despite similar levels of physical activity, patients exhibited poorer work ability and severe activity limitations.
DISABILITY AND REHABILITATION
(2023)
Article
Medicine, Research & Experimental
Mujgan Yilmaz, Andrea Thorn, Michala Skovlund Sorensen, Claus Lindkaer Jensen, Michael Mork Petersen
Summary: Sarcomas are rare malignant tumors treated with surgery, where negative pressure wound therapy (NPWT) has shown to reduce postoperative complications. A study compared NPWT with conventional wound dressing in surgical removal of deep-seated high-malignant STS, aiming to reduce wound complications.
Article
Surgery
Nizar Hamrouni, Jens Hjermind Hojvig, Michael Mork Petersen, Werner Hettwer, Lisa Toft Jensen, Christian Torsten Bonde
Summary: In patients with primary calcaneal malignancies, the radical treatment of amputation can lead to functional impairment and chronic pain. Total calcanectomy followed by reconstruction of the calcaneal defect is an alternative treatment method. This article presents a review of literature on calcaneal reconstruction and describes the application of a novel reconstructive technique utilizing a fibula flap within an allograft to reconstruct the calcaneus. The technique proved successful in two patients, resulting in complete bone union and satisfactory functional outcomes.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2023)
Article
Orthopedics
Afrim Iljazi, Michala Skovlund Sorensen, Thea Hovgaard Ladegaard, Soren Overgaard, Michael Mork Petersen
Summary: This retrospective study analyzed the incidence of dislocation in patients with metastatic bone disease after hip replacement surgery. The 1-year cumulative incidence of dislocation was 6.2%, with no significant difference between different articulating surfaces. Further research is needed to determine the potential benefits of specific articulations on the risk of postoperative dislocation in patients with metastatic bone disease.
Article
Medicine, Research & Experimental
Afrim Iljazi, Michala Skovlund Sorensen, Kolja Sebastian Weber, Allan Villadsen, Frank Eriksson, Michael Mork Petersen
Summary: This study aims to investigate whether dual mobility cup (DM) is non-inferior to constrained liner (CL) regarding the risk of post-operative dislocation in patients receiving total hip arthroplasty (THA) due to metastatic bone disease (MBD). This trial is the first of its kind and the knowledge gained will be crucial in guiding surgeons to choose a joint solution that minimizes the risk of dislocation and reduces the need for repeat surgeries in this patient population.
Article
Dermatology
Werner H. Hettwer, Chunsen Wu, Peter F. Horstmann, Claus L. Jensen, Anders Krarup-Hansen, Michael M. Petersen
Summary: Prolonged wound discharge can be reduced by occlusive wound closure in patients undergoing surgical treatment for metastatic bone disease involving the proximal femur. This randomized controlled trial showed that occlusive wound closure using Dermabond Prineo-22 resulted in a lower degree and shorter duration of postoperative wound discharge compared to routine wound closure with conventional skin staples. The study provides strong evidence that occlusive wound closure can effectively reduce the risk of wound discharge in high-risk patient populations.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Multidisciplinary Sciences
Peter Schwarzenberg, Thomas Colding-Rasmussen, Daniel J. Hutchinson, Dominic Mischler, Peter Horstmann, Michael Mork Petersen, Stine Jacobsen, Tatjana Pastor, Michael Malkoch, Christian Wong, Peter Varga
Summary: This study compared the biomechanical performance of a new light curable polymer composite with traditional metal plates, and found that the polymer composite is a viable solution for fracture fixation and has comparable mechanical properties to the metal plates under physiological loading values.
SCIENTIFIC REPORTS
(2023)
Article
Orthopedics
Thea H. Ladegaard, Michala S. Sorensen, Michael M. Petersen
Summary: This study aimed to investigate the 30-day mortality risk in patients with bone metastases who underwent endoprostheses or internal fixation surgery. The results showed that parameters describing the surgical trauma were not associated with 30-day mortality, but overall health status and extent of primary cancer influenced postoperative survival.
Editorial Material
Orthopedics
Ulrik Kahler Olesen, John E. Herzenberg, Klaus Hindso, Upender Martin Singh, Michael Mork Petersen
Article
Dermatology
Mathias Orholt, Kiya Abebe, Louise E. Rasmussen, Frederik L. Aaberg, Laerke J. Lindskov, Grethe Schmidt, Anne Lene Wagenblast, Michael M. Petersen, Anand C. Loya, Soren Daugaard, Mikkel Herly, David Hebbelstrup Jensen, Peter Vester-Glowinski
Summary: A standardized follow-up program for patients with atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) based on nationwide long-term estimates of local recurrence and metastasis in Denmark was recommended. Clinical visits for 4 years can be limited for AFX patients, while PDS patients should have clinical visits and PET/CT twice a year for the first 3 years and once a year for a minimum of 1 year.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2023)
Article
Orthopedics
Thomas Colding-Rasmussen, Peter F. Horstmann, Peter H. Jorgensen, Werner Hettwer, Bjarne H. Hansen, Christian Nai En Tierp-Wong, Michael M. Petersen
Summary: This study investigated whether the application of PMMA for bone defect reconstruction after intralesional curettage can improve the local recurrence rates of giant cell tumors. The results showed that the use of PMMA did not reduce the risk of local recurrence.
JOURNAL OF ORTHOPAEDIC SURGERY
(2023)
Article
Orthopedics
Kolja Sebastian Weber, Claus Lindkaer Jensen, Michael Mork Petersen
Summary: Percutaneous sclerotherapy with polidocanol appears to be a safe and effective alternative for the treatment of aneurysmal bone cysts, achieving healing or stable disease in 96% of cases.
WORLD JOURNAL OF ORTHOPEDICS
(2023)
Article
Biotechnology & Applied Microbiology
Thomas Colding-Rasmussen, Peter Schwarzenberg, Peter Frederik Horstmann, Casper Bent Smedegaard Ottesen, Jorge San Jacinto Garcia, Daniel John Hutchinson, Michael Malkoch, Michael Mork Petersen, Peter Varga, Christian Nai En Tierp-Wong
Summary: This study assessed the biomechanical variability and usability of the Bonevolent (TM) AdhFix osteosynthesis platform. The results showed consistent biomechanical stability and minimal variability both across and within surgeons, suggesting that the AdhFix platform can be learned and applied with minimal training.
BIOENGINEERING-BASEL
(2023)
Article
Orthopedics
T. H. Ladegaard, M. S. Sorensen, M. M. Petersen
Summary: This study aims to compare survival rates between patients with solitary and multiple bone metastases in the appendicular skeleton who underwent surgical treatment, and to investigate the impact of complete and incomplete resection (R0 and R1/R2) in patients with solitary metastasis.
BONE & JOINT JOURNAL
(2023)