Article
Surgery
Dougho Park, Jae Man Cho, Joong Won Yang, Donghoon Yang, Mansu Kim, Gayeoul Oh, Heum Dai Kwon
Summary: This study aimed to develop machine learning models for classifying expert-level therapeutic decisions in patients with degenerative cervical myelopathy (DCM). The study utilized various classification methods and machine learning algorithms to construct the models, and evaluated their performance using the area under the receiver operating characteristic curve (AUC-ROC). The results showed that the machine learning models were able to effectively classify DCM therapeutic options and could serve as a basis for establishing generalizable surgical decision models for DCM.
FRONTIERS IN SURGERY
(2022)
Article
Health Care Sciences & Services
Peter Obid, Anastasia Rakow, Gernot Michael Lang, Wolfgang Marx, Thomas Niemeyer, Tamim Rahim
Summary: This study evaluated the clinical and radiological outcomes of cervical disc arthroplasty (CDA) using the CP ESP(R) disc prosthesis in patients with cervical spondylotic myelopathy (CSM). The results showed that CDA achieved good clinical and radiological outcomes in these young patients, with preserved motion of the index segments. CDA may be a viable treatment option for selected patients with CSM.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, General & Internal
Chaojun Zhu, Jianhong Tao, Songquan Mo
Summary: This article reported a case of esophageal cervical spondylosis with cervical disc herniation, which achieved good results through surgical treatment, providing a treatment plan for similar cases.
Article
Clinical Neurology
Cylene Yang, Oliver D. Mowforth, Amir Rafati Fard, Benjamin M. Davies, Rodney J. C. Laing
Summary: Bilateral upper limb paraesthesia and pain are common symptoms of degenerative cervical myelopathy (DCM) and prompt investigation is necessary. This case presents a 72-year-old patient who developed sudden quadriplegia during a cervical spine MRI due to an intervertebral disc prolapse. Despite surgical decompression, the patient did not regain function and eventually died. This case highlights the devastating consequences of DCM and raises questions about its etiology.
BRITISH JOURNAL OF NEUROSURGERY
(2023)
Article
Clinical Neurology
Edward Goacher, Richard Phillips, Oliver D. Mowforth, Stefan Yordanov, Erlick A. C. Pereira, Adrian Gardner, Nasir A. Quraishi, Antony H. Bateman, Andreas K. Demetriades, Marcel Ivanov, Alexandru Budu, Edward Dyson, Guy Wynne-Jones, Benjamin M. Davies, Mark R. N. Kotter
Summary: The incidence of hospitalization for degenerative cervical myelopathy (DCM) is rising in England. Epidemiological data indicates that DCM primarily affects the working-age population. There is a significant gender difference, with a higher number of male patients than female patients. Early diagnosis and treatment should be strengthened to address the increasing burden of DCM.
ACTA NEUROCHIRURGICA
(2022)
Review
Orthopedics
Susan Hesni, David Baxter, Asif Saifuddin
Summary: This review provides a detailed description of the imaging features of cervical spondylotic myelopathy and radiculopathy, with a focus on MRI. It outlines grading systems of vertebral central canal and foraminal stenosis where relevant, and touches on imaging features recognized as predictors of clinical outcome and neurological recovery. This paper will serve as a reference for both radiologists and clinicians involved in the care of patients with cervical spondylotic myeloradiculopathy.
SKELETAL RADIOLOGY
(2023)
Article
Clinical Neurology
Maksim A. Shlykov, Erica M. Giles, Michael P. Kelly, Shiow J. Lin, Vy T. Pham, Nancy L. Saccone, Elizabeth L. Yanik
Summary: This study aimed to evaluate the associations between genetic and nongenetic factors and degenerative cervical myelopathy (DCM). The study identified age, sex, and relative socioeconomic deprivation as independent risk factors for DCM, while Asian race was inversely associated. Additionally, potential SNP markers were found in the GTPBP1 gene on chromosome 22 and an intergenic region on chromosome 18. These findings contribute to understanding the disease processes, guiding prevention and interventions, and potentially influencing surgical outcomes for DCM.
Article
Clinical Neurology
Yi-Wei Shen, Yi Yang, Hao Liu, Bei-Yu Wang, Chen Ding, Yang Meng, Xin Rong, Ying Hong
Summary: This study found that preoperative cervical spondylosis predominantly affected the heterotopic ossification formation in the posterior disc space after cervical disc replacement (CDR). Disc height loss was identified as an independent risk factor for the formation of posterior HO.
GLOBAL SPINE JOURNAL
(2022)
Article
Computer Science, Information Systems
M. Sreeraj, Jestin Joy, Manu Jose, Meenu Varghese, T. J. Rejoice
Summary: Cervical Spondylosis is a chronic spinal condition that can be difficult to diagnose in early stages, but primary care detection can reduce the risk. Machine learning techniques can provide a low-cost, accurate mechanism for early stage spondylosis detection.
JOURNAL OF KING SAUD UNIVERSITY-COMPUTER AND INFORMATION SCIENCES
(2022)
Review
Geriatrics & Gerontology
Ben Grodzinski, Rory Durham, Oliver Mowforth, Daniel Stubbs, Mark R. N. Kotter, Benjamin M. Davies
Summary: The study found that age is a significant predictor in affecting the clinical presentation, surgical management, and post-operative outcomes of degenerative cervical myelopathy (DCM). Older patients with DCM tend to have worse pre-operative functional status, are more likely to undergo posterior surgery, and have worse post-operative functional status but experience a similar amount of improvement as younger patients. The findings emphasize the importance of considering age when determining the eligibility of older patients for surgery.
Article
Clinical Neurology
Benjamin M. Davies, Oliver Mowforth, Helen Wood, Zahabiya Karimi, Iwan Sadler, Lindsay Tetreault, Jamie Milligan, Jamie R. F. Wilson, Sukhvinder Kalsi-Ryan, Julio C. Furlan, Yoshiharu Kawaguchi, Manabu Ito, Carl Moritz Zipser, Timothy F. Boerger, Alexander R. Vaccaro, Rory K. J. Murphy, Mike Hutton, Ricardo Rodrigues-Pinto, Paul A. Koljonen, James S. Harrop, Bizhan Aarabi, Vafa Rahimi-Movaghar, Shekar N. Kurpad, James D. Guest, Jefferson R. Wilson, Brian K. Kwon, Mark R. N. Kotter, Michael G. Fehlings
Summary: This article reviews the importance of raising awareness for Degenerative Cervical Myelopathy (DCM) as the number one research priority. It highlights the low level of awareness, long diagnosis waiting times, and limited research funding for DCM. Drawing parallels from successful cases in stroke and acute coronary syndrome, the article emphasizes the need to raise awareness and make DCM a public health priority internationally.
GLOBAL SPINE JOURNAL
(2022)
Article
Clinical Neurology
Ricardo Rodrigues-Pinto, Thiago S. Montenegro, Benjamin M. Davies, So Kato, Yoshiharu Kawaguchi, Manabu Ito, Mehmet Zileli, Brian K. Kwon, Michael G. Fehlings, Paul A. Koljonen, Shekar N. Kurpad, James D. Guest, Bizhan Aarabi, Vafa Rahimi-Movaghar, Jefferson R. Wilson, Mark R. N. Kotter, James S. Harrop
Summary: The study introduces individualized surgery as a research priority for Degenerative Cervical Myelopathy. The article summarizes current surgical recommendations and indications, and discusses the impact of prognostic factors on surgical outcomes. It highlights the potential of surgical decompression to improve neurologic function and quality of life for most patients, but acknowledges the uncertainties regarding surgical types and timing.
GLOBAL SPINE JOURNAL
(2022)
Article
Medicine, General & Internal
Talia C. Oughourlian, Chencai Wang, Noriko Salamon, Langston T. Holly, Benjamin M. Ellingson
Summary: In patients with DCM, males have larger gray matter volume (GMV) in motor, language, and vision related brain regions compared to female DCM patients. Males show a significant positive correlation between GMV and mJOA score, with worsening neurological symptoms leading to decreasing GMV primarily in somatosensory and motor related cortical regions. Females exhibit a similar association, involving a broader range of cortical areas including those involved in pain processing. Additionally, female patients consistently show smaller GMV in sensorimotor regions compared with male patients, regardless of mJOA score. Results indicate strong sex-related differences in cortical volume in patients with DCM, potentially reflecting hormonal influence or differing compensation mechanisms.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Orthopedics
Huachuan Wu, Guoliang Chen, Xianlong Li, Zhengya Zhu, Zuofeng Xu, Xizhe Liu, Shaoyu Liu
Summary: This study compares the reliability of two different methods for evaluating the hyperechoic intensity of spinal cord ultrasound in degenerative cervical myelopathy. The images-based GVR-B method demonstrates better reliability and can be used for prognostic prediction and future studies.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Clinical Neurology
Domagoj Coric, Richard D. Guyer, Hyun Bae, Pierce D. Nunley, K. Brandon Strenge, John H. Peloza, Margaret O. Boltes, Donna D. Ohnmeiss
Summary: The study evaluated the safety and efficacy of a PEEK-on-ceramic cervical total disc replacement device for 2-level cervical disc disease. Results showed that cTDR had a superior success rate compared to ACDF in treating patients with radiculopathy or myelopathy, while maintaining motion in the cervical spine.
JOURNAL OF NEUROSURGERY-SPINE
(2022)
Review
Clinical Neurology
Jayson Lian, Nicole Levine, Woojin Cho
EUROPEAN SPINE JOURNAL
(2018)
Article
Engineering, Biomedical
Bruce E. Dall, Sonia Eden, Woojin Cho, Alexa Karkenny, Daina M. Brooks, Gerald M. Hayward, Mark Moldavsky, Soumya Yandamuri, Brandon S. Bucklen
CLINICAL BIOMECHANICS
(2019)
Review
Clinical Neurology
Brittany A. Oster, Sina Rashidi Kikanloo, Nicole L. Levine, Jayson Lian, Woojin Cho
Article
Infectious Diseases
Hayeem L. Rudy, Woojin Cho, Brittany A. Oster, Matthew T. Morris, Jacob Schulz
SURGICAL INFECTIONS
(2020)
Review
Clinical Neurology
Brittany A. Oster, Sina Rashidi Kikanloo, Nicole L. Levine, Jayson Lian, Woojin Cho
Review
Clinical Neurology
Brittany A. Oster, Sina Rashidi Kikanloo, Nicole L. Levine, Jayson Lian, Woojin Cho
Article
Medicine, General & Internal
Hong Jin Kim, Jae Hyuk Yang, Dong-Gune Chang, Se-Il Suk, Seung Woo Suh, Ji Su Kim, Sang-Il Kim, Kwang-Sup Song, Woojin Cho
Summary: In AIS patients undergoing deformity correction with PSI, RD, and DVR, the incidence of PJK was 10.1%, with associations found between PJK development and TL/L curve pattern and over-correction of the proximal curve. Careful evaluation of compensatory curves is important in preventing PJK.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Hong Jin Kim, Jae Hyuk Yang, Dong-Gune Chang, Seung Woo Suh, Hoon Jo, Sang-Il Kim, Kwang-Sup Song, Woojin Cho
Summary: For patients with concurrent KOA and LSD, preoperative TKA combined with spinal fusion surgery can lead to improved radiological and clinical outcomes postoperatively, especially benefiting those with severe abnormalities in sagittal spinopelvic parameters.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Clinical Neurology
Hayeem L. Rudy, David Yang, Andrew D. Nam, Woojin Cho
GLOBAL SPINE JOURNAL
(2019)
Review
Clinical Neurology
Keonhee Kim, Joseph Mendelis, Woojin Cho
GLOBAL SPINE JOURNAL
(2019)
Review
Clinical Neurology
Nicholas Shepard, Woojin Cho
GLOBAL SPINE JOURNAL
(2019)
Review
Clinical Neurology
Jimmy J. Chan, Nicholas Shepard, Woojin Cho
GLOBAL SPINE JOURNAL
(2019)
Article
Clinical Neurology
Matthew T. Morris, Jonathan Morris, Camari Wallace, Woojin Cho, Alok Sharan, Manal Abouelrigal, Vilma Joseph
GLOBAL SPINE JOURNAL
(2019)
Review
Orthopedics
Sina Rashidi Kikanloo, Sandip Parshottam Tarpada, Woojin Cho
ASIAN SPINE JOURNAL
(2019)
Article
Orthopedics
Jung Hwan Kim, Alok Sharan, Woojin Cho, Mohammed Emam, Michael Hagen, Soo Yeon Kim
ASIAN SPINE JOURNAL
(2019)