Loss of Munc18-1 long splice variant in GABAergic terminals is associated with cognitive decline and increased risk of dementia in a community sample

Increased SNARE Protein-Protein Interactions in Orbitofrontal and Anterior Cingulate Cortices in Schizophrenia

(2015) Alfredo Ramos-Miguel et al.   BIOLOGICAL PSYCHIATRY

Exercise prevents downregulation of hippocampal presynaptic proteins following olanzapine-elicited metabolic dysregulation in rats: Distinct roles of inhibitory and excitatory terminals

(2015) A. Ramos-Miguel et al.   NEUROSCIENCE

Synaptic Effects of Munc18-1 Alternative Splicing in Excitatory Hippocampal Neurons

(2015) Marieke Meijer et al.   PLoS One

Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner

(2014) Tony Cijsouw et al.   JOURNAL OF CELL BIOLOGY

Evidence for morphological alterations in prefrontal white matter glia in schizophrenia and bipolar disorder

(2014) Christa Hercher et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer's disease

(2014) Nicole C. Berchtold et al.   NEUROBIOLOGY OF AGING

Much of late life cognitive decline is not due to common neurodegenerative pathologies

(2013) Patricia A. Boyle et al.   ANNALS OF NEUROLOGY

Overview and Findings from the Rush Memory and Aging Project

(2013) David A. Bennett et al.   Current Alzheimer Research

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

(2013) Thomas C. Südhof   NEURON

Predominant loss of glutamatergic terminal markers in a β-amyloid peptide model of Alzheimer's disease

(2013) Paula M. Canas et al.   NEUROPHARMACOLOGY

Effects of chronic exercise and treatment with the antipsychotic drug olanzapine on hippocampal volume in adult female rats

(2013) A.M. Barr et al.   NEUROSCIENCE

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease

(2013) B. Bai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia

(2013) L Urigüen et al.   Translational Psychiatry

The Membrane Fusion Enigma: SNAREs, Sec1/Munc18 Proteins, and Their Accomplices—Guilty as Charged?

(2012) Josep Rizo et al.   Annual Review of Cell and Developmental Biology

Accumulation of  -Synuclein Triggered by Presynaptic Dysfunction

(2012) Y. Nakata et al.   JOURNAL OF NEUROSCIENCE

Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study

(2012) Anita Rauch et al.   LANCET

Loss of functional GABAA receptors in the Alzheimer diseased brain

(2012) A. Limon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease

(2012) Laura E. Donovan et al.   Proteomics Clinical Applications

Proteasome Inhibition Alleviates SNARE-Dependent Neurodegeneration

(2012) M. Sharma et al.   Science Translational Medicine

Cognitive reserve, presynaptic proteins and dementia in the elderly

(2012) W G Honer et al.   Translational Psychiatry

Intellectual disability without epilepsy associated with STXBP1 disruption

(2011) Fadi F Hamdan et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Regulation of munc18-1 and syntaxin-1A interactive partners in schizophrenia prefrontal cortex: down-regulation of munc18-1a isoform and 75 kDa SNARE complex after antipsychotic treatment

(2011) Itziar Gil-Pisa et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Identification of Novel α-Synuclein Isoforms in Human Brain Tissue by using an Online NanoLC-ESI-FTICR-MS Method

(2011) Annika Öhrfelt et al.   NEUROCHEMICAL RESEARCH

Munc18-1 as a key regulator of neurosecretion

(2010) Gayoung A. Han et al.   JOURNAL OF NEUROCHEMISTRY

Clinical spectrum of early-onset epileptic encephalopathies associated with STXBP1 mutations

(2010) L. Deprez et al.   NEUROLOGY

A Novel Mechanism and Treatment Target for Presynaptic Abnormalities in Specific Striatal Regions in Schizophrenia

(2010) Vilte E Barakauskas et al.   NEUROPSYCHOPHARMACOLOGY

De novoSTXBP1mutations in mental retardation and nonsyndromic epilepsy

(2009) Fadi F. Hamdan et al.   ANNALS OF NEUROLOGY

The neuropathology of probable Alzheimer disease and mild cognitive impairment

(2009) Julie A. Schneider et al.   ANNALS OF NEUROLOGY

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression

(2008) ÁT Behan et al.   MOLECULAR PSYCHIATRY

De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy

(2008) Hirotomo Saitsu et al.   NATURE GENETICS