Glutaminase-containing microvesicles from HIV-1-infected macrophages and immune-activated microglia induce neurotoxicity

The Neutral Sphingomyelinase Pathway Regulates Packaging of the Prion Protein into Exosomes

(2014) Belinda B. Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles

(2013) P Joshi et al.   CELL DEATH AND DIFFERENTIATION

IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase

(2013) Ling Ye et al.   JOURNAL OF NEUROCHEMISTRY

Extracellular vesicles as mediators of neuron-glia communication

(2013) Carsten Frühbeis et al.   Frontiers in Cellular Neuroscience

Myeloid microvesicles are a marker and therapeutic target for neuroinflammation

(2012) Claudia Verderio et al.   ANNALS OF NEUROLOGY

Exosomes: the ideal nanovectors for biodelivery

(2012) Stefano Fais et al.   BIOLOGICAL CHEMISTRY

HIV-1 infection–induced apoptotic microparticles inhibit human DCs via CD44

(2012) Davor Frleta et al.   JOURNAL OF CLINICAL INVESTIGATION

Biochemical and Biologic Characterization of Exosomes and Microvesicles as Facilitators of HIV-1 Infection in Macrophages

(2012) I. Kadiu et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial Glutaminase Release Contributes to Glutamate-Mediated Neurotoxicity during Human Immunodeficiency Virus-1 Infection

(2012) Changhai Tian et al.   Journal of Neuroimmune Pharmacology

RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells

(2012) B Li et al.   ONCOGENE

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

(2012) K. Thangavelu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism

(2012) A. Cassago et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain Tumor Microvesicles: Insights into Intercellular Communication in the Nervous System

(2011) Kristan E. van der Vos et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease

(2011) Sudad Saman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutaminase Dysregulation in HIV-1-Infected Human Microglia Mediates Neurotoxicity: Relevant to HIV-1-Associated Neurocognitive Disorders

(2011) Y. Huang et al.   JOURNAL OF NEUROSCIENCE

HIV-1 Clade B and C Isolates Exhibit Differential Replication: Relevance to Macrophage-Mediated Neurotoxicity

(2011) Agnes A. Constantino et al.   NEUROTOXICITY RESEARCH

Alterations in Platelet Function and Cell-Derived Microvesicles in Recently Menopausal Women: Relationship to Metabolic Syndrome and Atherogenic Risk

(2011) Muthuvel Jayachandran et al.   Journal of Cardiovascular Translational Research

HIV Type 1 Nef Is Released from Infected Cells in CD45+ Microvesicles and Is Present in the Plasma of HIV-Infected Individuals

(2010) A.D. Raymond et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders

(2009) Nicholas P. Whitney et al.   JOURNAL OF NEUROCHEMISTRY

In vitroglutaminase regulation and mechanisms of glutamate generation in HIV-1-infected macrophage

(2009) Nathan Erdmann et al.   JOURNAL OF NEUROCHEMISTRY

Sphingosine Facilitates SNARE Complex Assembly and Activates Synaptic Vesicle Exocytosis

(2009) Frédéric Darios et al.   NEURON

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

HIV-infected macrophages mediate neuronal apoptosis through mitochondrial glutaminase

(2008) Changhai Tian et al.   JOURNAL OF NEUROCHEMISTRY

HIV Infection of the Central Nervous System: Clinical Features and Neuropathogenesis

(2008) Lysa Boissé et al.   NEUROLOGIC CLINICS

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE