Neuroprotection of Sevoflurane Against Ischemia/Reperfusion-Induced Brain Injury Through Inhibiting JNK3/Caspase-3 by Enhancing Akt Signaling Pathway

PRAS40 plays a pivotal role in protecting against stroke by linking the Akt and mTOR pathways

(2014) Xiaoxing Xiong et al.   NEUROBIOLOGY OF DISEASE

Neuroprotective effect of pAkt and HIF-1 α on ischemia rats

(2014) Bao-Nan Liu et al.   Asian Pacific Journal of Tropical Medicine

Astragalus injection protects cerebral ischemic injury by inhibiting neuronal apoptosis and the expression of JNK3 after cerebral ischemia reperfusion in rats

(2013) Guangyi Liu et al.   Behavioral and Brain Functions

Behavior outcome after ischemic and hemorrhagic stroke, with similar brain damage, in rats

(2013) Régis Gemerasca Mestriner et al.   BEHAVIOURAL BRAIN RESEARCH

miR-15b Suppression of Bcl-2 Contributes to Cerebral Ischemic Injury and is Reversed by Sevoflurane Preconditioning

(2013) Hong Shi et al.   CNS & Neurological Disorders-Drug Targets

Preconditioning with sevoflurane ameliorates spatial learning and memory deficit after focal cerebral ischemia–reperfusion in rats

(2013) Xianwen Hu et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Mitochondrial JNK phosphorylation as a novel therapeutic target to inhibit neuroinflammation and apoptosis after neonatal ischemic brain damage

(2013) Cora H. Nijboer et al.   NEUROBIOLOGY OF DISEASE

Activation of Canonical Notch Signaling Pathway Is Involved in the Ischemic Tolerance Induced by Sevoflurane Preconditioning in Mice

(2012) Qianzi Yang et al.   ANESTHESIOLOGY

Association of DJ-1/PTEN/AKT- and ASK1/p38-mediated cell signalling with ischaemic cardiomyopathy

(2012) Jelena Klawitter et al.   CARDIOVASCULAR RESEARCH

The Neuroprotective Effect of Losartan through Inhibiting AT1/ASK1/MKK4/JNK3 Pathway Following Cerebral I/R in Rat Hippocampal CA1 Region

(2012) Tian-Ling Zhang et al.   CNS Neuroscience & Therapeutics

Sevoflurane and Isoflurane Preconditioning Provides Neuroprotection by Inhibition of Apoptosis-related mRNA Expression in a Rat Model of Focal Cerebral Ischemia

(2012) Nurdan Bedirli et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

The effects of metabotropic glutamate receptor 7 allosteric agonist N,N′-dibenzhydrylethane-1,2-diamine dihydrochloride on developmental sevoflurane neurotoxicity: role of extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase signaling pathway

(2012) W.-Y. Wang et al.   NEUROSCIENCE

Sevoflurane Preconditioning Induces Neuroprotection Through Reactive Oxygen Species-Mediated Up-Regulation of Antioxidant Enzymes in Rats

(2011) Qianzi Yang et al.   ANESTHESIA AND ANALGESIA

Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways

(2011) Jose R. Bayascas   CELL CYCLE

Diet-induced obesity suppresses sevoflurane preconditioning against myocardial ischemia–reperfusion injury: role of AMP-activated protein kinase pathway

(2011) Tao Song et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Gene expression profile in JNK3 null mice: a novel specific activation of the PI3K/AKT pathway

(2011) Fèlix Junyent et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of Sevoflurane Postconditioning Against Cerebral Ischemia Reperfusion-Induced Oxidative Injury in Rats

(2011) Yan Zhang et al.   MOLECULES

Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation

(2011) Zhi Ye et al.   NEUROLOGICAL SCIENCES

Protective Effect of FK506 on Myocardial Ischemia/Reperfusion Injury by Suppression of CaN and ASK1 Signaling Circuitry

(2010) Xing Feng et al.   Cardiovascular Toxicology

The neuroprotective effects of the seeds of Cassia obtusifolia on transient cerebral global ischemia in mice

(2009) Dong Hyun Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Dual inhibitory roles of geldanamycin on the c-Jun NH2-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activation of Akt in ischemic brain injury

(2008) X.-R. Wen et al.   NEUROSCIENCE