Bis(propyl)-cognitin Prevents β-amyloid-induced Memory Deficits as Well as Synaptic Formation and Plasticity Impairments via the Activation of PI3-K Pathway

The Amyloid-β Oligomer Count in Cerebrospinal Fluid is a Biomarker for Alzheimer's Disease

(2018) Lei Wang-Dietrich et al.   JOURNAL OF ALZHEIMERS DISEASE

Rosiglitazone Prevents Amyloid-β Oligomer-Induced Impairment of Synapse Formation and Plasticity via Increasing Dendrite and Spine Mitochondrial Number

(2018) Shujun Xu et al.   JOURNAL OF ALZHEIMERS DISEASE

Altered GluN2B NMDA receptor function and synaptic plasticity during early pathology in the PS2APP mouse model of Alzheimer's disease

(2015) Jesse E. Hanson et al.   NEUROBIOLOGY OF DISEASE

NGF but not BDNF overexpression protects hippocampal LTP from beta-amyloid-induced impairment

(2015) A.D. Ivanov et al.   NEUROSCIENCE

Synaptic Therapy in Alzheimer’s Disease: A CREB-centric Approach

(2015) Andrew F. Teich et al.   Neurotherapeutics

Cerebrospinal fluid β-amyloid and phospho-tau biomarker interactions affecting brain structure in preclinical Alzheimer disease

(2014) Juan Fortea et al.   ANNALS OF NEUROLOGY

Pathways to Alzheimer's disease

(2014) J. Hardy et al.   JOURNAL OF INTERNAL MEDICINE

Baicalin attenuates Alzheimer-like pathological changes and memory deficits induced by amyloid β1–42 protein

(2014) Chong Chen et al.   METABOLIC BRAIN DISEASE

Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease

(2014) Shichun Tu et al.   Molecular Neurodegeneration

Rosiglitazone prevents the memory deficits induced by amyloid-beta oligomers via inhibition of inflammatory responses

(2014) Shujun Xu et al.   NEUROSCIENCE LETTERS

Role of synaptic phosphatidylinositol 3-kinase in a behavioral learning response in C. elegans

(2014) H. Ohno et al.   SCIENCE

Substantial Neuroprotection Against K+Deprivation-Induced Apoptosis in Primary Cerebellar Granule Neurons by Novel Dimer Bis(propyl)-Cognitin Via the Activation of VEGFR-2 Signaling Pathway

(2013) Sheng-Quan Hu et al.   CNS Neuroscience & Therapeutics

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

(2012) P. E. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease

(2012) A. O. Ardiles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessment of cognition in early dementia

(2011) Nina B. Silverberg et al.   Alzheimers & Dementia

Alzheimer's Disease Brain-Derived Amyloid- -Mediated Inhibition of LTP In Vivo Is Prevented by Immunotargeting Cellular Prion Protein

(2011) A. E. Barry et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's disease: synapses gone cold

(2011) Robert M Koffie et al.   Molecular Neurodegeneration

Hippocampal synaptic plasticity in Alzheimer’s disease: what have we learned so far from transgenic models?

(2011) Cristina Marchetti et al.   REVIEWS IN THE NEUROSCIENCES

Pathologically Activated Neuroprotection via Uncompetitive Blockade ofN-Methyl-d-aspartate Receptors with Fast Off-rate by Novel Multifunctional Dimer Bis(propyl)-cognitin

(2010) Jialie Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alzheimer's Biomarker Initiative Hits Its Stride

(2009) G. Miller   SCIENCE

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH

Phosphatidylinositol-3-kinase activation blocks amyloid beta-induced neurotoxicity

(2007) Kyu-Yong Lee et al.   TOXICOLOGY