Looks can be deceiving: recent insights into the mechanism of protein secretion by the autotransporter pathway

Multiple Driving Forces Required for Efficient Secretion of Autotransporter Virulence Proteins

(2015) Igor Drobnak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Going beyond E. coli: autotransporter based surface display on alternative host organisms

(2015) Iasson E.P. Tozakidis et al.   New Biotechnology

Decoration of Outer Membrane Vesicles with Multiple Antigens by Using an Autotransporter Approach

(2014) Maria H. Daleke-Schermerhorn et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Autotransporter-Based Antigen Display in Bacterial Ghosts

(2014) Anna Hjelm et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Detecting Envelope Stress by Monitoring β-Barrel Assembly

(2014) Seung-Hyun Cho et al.   CELL

An autotransporter display platform for the development of multivalent recombinant bacterial vector vaccines

(2014) Wouter SP Jong et al.   Microbial Cell Factories

An engineered autotransporter-based surface expression vector enables efficient display of Affibody molecules on OmpT-negative E. coli as well as protease-mediated secretion in OmpT-positive strains

(2014) Filippa Fleetwood et al.   Microbial Cell Factories

Of linkers and autochaperones: an unambiguous nomenclature to identify common and uncommon themes for autotransporter secretion

(2014) Igor Drobnak et al.   MOLECULAR MICROBIOLOGY

Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG

(2014) Parveen Goyal et al.   NATURE

Transmembrane domain of surface-exposed outer membrane lipoprotein RcsF is threaded through the lumen of  -barrel proteins

(2014) A. Konovalova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lateral Opening and Exit Pore Formation Are Required for BamA Function

(2014) Nicholas Noinaj et al.   STRUCTURE

Versatile in vitro system to study translocation and functional integration of bacterial outer membrane proteins

(2014) Derrick Norell et al.   Nature Communications

A mortise–tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

(2014) Denisse L. Leyton et al.   Nature Communications

Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes

(2014) Hsin-Hui Shen et al.   Nature Communications

Translocation path of a substrate protein through its Omp85 transporter

(2014) Catherine Baud et al.   Nature Communications

Reconstitution of bacterial autotransporter assembly using purified components

(2014) Giselle Roman-Hernandez et al.   eLife

A comprehensive analysis of the Omp85/TpsB protein superfamily structural diversity, taxonomic occurrence, and evolution

(2014) Eva Heinz et al.   Frontiers in Microbiology

A Trimeric Lipoprotein Assists in Trimeric Autotransporter Biogenesis in Enterobacteria

(2013) Iwan Grin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stepwise Folding of an Autotransporter Passenger Domain Is Not Essential for Its Secretion

(2013) Wanyoike Kang'ethe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An alternative outer membrane secretion mechanism for an autotransporter protein lacking a C-terminal stable core

(2013) Richard N. Besingi et al.   MOLECULAR MICROBIOLOGY

Structural and energetic basis of folded-protein transport by the FimD usher

(2013) Sebastian Geibel et al.   NATURE

Structural insight into the biogenesis of β-barrel membrane proteins

(2013) Nicholas Noinaj et al.   NATURE

The structural basis of autotransporter translocation by TamA

(2013) Fabian Gruss et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sequential Unfolding of Beta Helical Protein by Single-Molecule Atomic Force Microscopy

(2013) David Alsteens et al.   PLoS One

Charge-dependent secretion of an intrinsically disordered protein via the autotransporter pathway

(2013) W. Kang'ethe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping

(2013) B. Heras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic link between   barrel assembly and the initiation of autotransporter secretion

(2013) O. Pavlova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A generalised module for the selective extracellular accumulation of recombinant proteins

(2012) Yanina R Sevastsyanovich et al.   Microbial Cell Factories

A structurally informed autotransporter platform for efficient heterologous protein secretion and display

(2012) Wouter SP Jong et al.   Microbial Cell Factories

Structural basis for iron piracy by pathogenic Neisseria

(2012) Nicholas Noinaj et al.   NATURE

Discovery of an archetypal protein transport system in bacterial outer membranes

(2012) Joel Selkrig et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Type V secretion: mechanism(s) of autotransport through the bacterial outer membrane

(2012) J. C. Leo et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Bioinformatic Strategy for the Detection, Classification and Analysis of Bacterial Autotransporters

(2012) Nermin Celik et al.   PLoS One

Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis

(2012) James W. Fairman et al.   STRUCTURE

Autotransporter passenger domain secretion requires a hydrophobic cavity at the extracellular entrance of the β-domain pore

(2011) Yujia Zhai et al.   BIOCHEMICAL JOURNAL

The Essential  -Barrel Assembly Machinery Complex Components BamD and BamA Are Required for Autotransporter Biogenesis

(2011) A. E. Rossiter et al.   JOURNAL OF BACTERIOLOGY

Size and Conformation Limits to Secretion of Disulfide-bonded Loops in Autotransporter Proteins

(2011) Denisse L. Leyton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autotransporter ?-Domains Have a Specific Function in Protein Secretion beyond Outer-Membrane Targeting

(2011) Ana Saur et al.   JOURNAL OF MOLECULAR BIOLOGY

Estimating the Size of the Active Translocation Pore of an Autotransporter

(2011) Ana Saurí et al.   JOURNAL OF MOLECULAR BIOLOGY

Sequential and spatially restricted interactions of assembly factors with an autotransporter   domain

(2011) R. Ieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure of E. coli IgG-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins

(2011) Jack C. Leo et al.   STRUCTURE

A Conserved Aromatic Residue in the Autochaperone Domain of the Autotransporter Hbp Is Critical for Initiation of Outer Membrane Translocation

(2010) Zora Soprova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YidC Is Involved in the Biogenesis of the Secreted Autotransporter Hemoglobin Protease

(2010) Wouter S. P. Jong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis for the Structural Stability of an Enclosed β-Barrel Loop

(2010) Pu Tian et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structure of a Full-Length Autotransporter

(2010) Bert van den Berg   JOURNAL OF MOLECULAR BIOLOGY

A Novel Intein-Like Autoproteolytic Mechanism in Autotransporter Proteins

(2010) Nami Tajima et al.   JOURNAL OF MOLECULAR BIOLOGY

High-throughput Sorting of an Anticalin Library via EspP-mediated Functional Display on the Escherichia coli Cell Surface

(2010) Uli Binder et al.   JOURNAL OF MOLECULAR BIOLOGY

Dissection of β-barrel outer membrane protein assembly pathways through characterizing BamA POTRA 1 mutants of Escherichia coli

(2010) Drew Bennion et al.   MOLECULAR MICROBIOLOGY

Secretion of a bacterial virulence factor is driven by the folding of a C-terminal segment

(2010) Janine H. Peterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of Outer Membrane Protein Assembly from Purified Components

(2010) C. L. Hagan et al.   SCIENCE

Roles of Periplasmic Chaperone Proteins in the Biogenesis of Serine Protease Autotransporters of Enterobacteriaceae

(2009) F. Ruiz-Perez et al.   JOURNAL OF BACTERIOLOGY

The Bam (Omp85) complex is involved in secretion of the autotransporter haemoglobin protease

(2009) A. Sauri et al.   MICROBIOLOGY-SGM

Vectorial transport and folding of an autotransporter virulence protein during outer membrane secretion

(2009) Mirco Junker et al.   MOLECULAR MICROBIOLOGY

Interaction of an autotransporter passenger domain with BamA during its translocation across the bacterial outer membrane

(2009) Raffaele Ieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cavity-chaperone Skp protects its substrate from aggregation but allows independent folding of substrate domains

(2009) Troy A. Walton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A conserved stable core structure in the passenger domain β-helix of autotransporter virulence proteins

(2008) Jonathan P. Renn et al.   BIOPOLYMERS

Chlamydia trachomatis Polymorphic Membrane Protein D Is an Oligomeric Autotransporter with a Higher-Order Structure

(2008) K. A. Swanson et al.   INFECTION AND IMMUNITY