Journal
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
Volume 15, Issue 10, Pages 1359-1361Publisher
INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D)
DOI: 10.5588/ijtld.11.0092
Keywords
tuberculosis; control; child
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This prospective study enrolled children aged <5 years with reported contact with adult tuberculosis (TB) patients in Angola. The study sample consisted of 124 children: 70 (56.5%) were active TB cases, 22 (17.7%) had latent TB infection (LTBI) and 32 (25.8%) were TB-exposed; 14 (20%) were human immunodeficiency virus positive. After 6 months of follow-up, 31.8% of the LTBI cases had evolved to active TB and 9.4% of the non-infected children had developed active TB. The strategy of simultaneous chest X-ray and TB skin test used in this study was effective; despite this protocol, however, 31.8% LTBI children developed active TB.
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