Pulmonary Fibrosis Inducer, Bleomycin, Causes Redox-Sensitive Activation of Phospholipase D and Cytotoxicity Through Formation of Bioactive Lipid Signal Mediator, Phosphatidic Acid, in Lung Microvascular Endothelial Cells

Bleomycin induces the extrinsic apoptotic pathway in pulmonary endothelial cells

(2010) Ognoon Mungunsukh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

LPA3, a unique G protein-coupled receptor for lysophosphatidic acid

(2010) Kotaro Hama et al.   PROGRESS IN LIPID RESEARCH

Bleomycin and its Role in Inducing Apoptosis and Senescence in Lung Cells - Modulating Effects of Caveolin-1

(2009) Michael Kasper et al.   CURRENT CANCER DRUG TARGETS

Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis

(2009) Wenjuan Su et al.   Future Oncology

Calcium and Calmodulin Regulate Mercury-induced Phospholipase D Activation in Vascular Endothelial Cells

(2009) Alon Peltz et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Pulmonary fibrosis: pathogenesis, etiology and regulation

(2009) M S Wilson et al.   Mucosal Immunology

Exposures and Idiopathic Lung Disease

(2009) Varsha Taskar et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Oxidation of extracellular cysteine/cystine redox state in bleomycin-induced lung fibrosis

(2008) Smita S. Iyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Oxidant–Antioxidant Imbalance as a Potential Contributor to the Progression of Human Pulmonary Fibrosis

(2008) Vuokko L. Kinnula et al.   ANTIOXIDANTS & REDOX SIGNALING

Disruption of iron homeostasis and lung disease

(2008) Andrew J. Ghio   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Two pathways for lysophosphatidic acid production

(2008) J AOKI   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Role of Lipid-Derived Free Radical in Bleomycin-Induced Lung Injury in Mice: Availability for ESR Spin Trap Method with Organic Phase Extraction

(2008) Keizo Sato et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions

(2008) Angel Catalá   CHEMISTRY AND PHYSICS OF LIPIDS

Lysophosphatidic Acid Receptors 1 and 2 Play Roles in Regulation of Vascular Injury Responses but Not Blood Pressure

(2008) Manikandan Panchatcharam et al.   CIRCULATION RESEARCH

Protein Kinase Inhibitors in the Treatment of Pulmonary Fibrosis

(2008) Sylvie Garneau-Tsodikova et al.   CURRENT MEDICINAL CHEMISTRY

Caveolae and Caveolins in the Respiratory System

(2008) Reinoud Gosens et al.   CURRENT MOLECULAR MEDICINE

Pulmonary hypertension in interstitial lung disease

(2008) J. Behr et al.   EUROPEAN RESPIRATORY JOURNAL

Therapeutic potential of inhaled p38 mitogen-activated protein kinase inhibitors for inflammatory pulmonary diseases

(2008) Puneet Chopra et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Redox-active antioxidant modulation of lipid signaling in vascular endothelial cells: vitamin C induces activation of phospholipase D through phospholipase A2, lipoxygenase, and cyclooxygenase

(2008) Emily Steinhour et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a Phospholipase D Pharmacological Inhibitor That Alters Cell Spreading and Inhibits Chemotaxis

(2008) W. Su et al.   MOLECULAR PHARMACOLOGY

Murine models of pulmonary fibrosis

(2007) Bethany B. Moore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

(2007) Antje Moeller et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Attenuation of bleomycin-induced lung injury and oxidative stress by N-acetylcysteine plus deferoxamine

(2007) Kelly C. Teixeira et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS