Regulation of the Ca2+-ATPase by cholesterol: A specific or non-specific effect?

Lipid–protein interactions

(2015) Anthony G. Lee   BIOCHEMICAL SOCIETY TRANSACTIONS

SERCA mutant E309Q binds two Ca2+ions but adopts a catalytically incompetent conformation

(2013) Johannes D Clausen et al.   EMBO JOURNAL

The Structural Basis for Phospholamban Inhibition of the Calcium Pump in Sarcoplasmic Reticulum

(2013) Brandy L. Akin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Water-Mediated Interactions Influence the Binding of Thapsigargin to Sarco/Endoplasmic Reticulum Calcium Adenosinetriphosphatase

(2013) Eleonora S. Paulsen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evidence for Cardiolipin Binding Sites on the Membrane-Exposed Surface of the Cytochrome bc1

(2013) Clement Arnarez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 state

(2013) Chikashi Toyoshima et al.   NATURE

The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm

(2013) Anne-Marie L. Winther et al.   NATURE

Cholesterol increases kinetic, energetic, and mechanical stability of the human  2-adrenergic receptor

(2012) M. Zocher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy

(2012) S. R. Denmeade et al.   Science Translational Medicine

Protonation States of Important Acidic Residues in the Central Ca2+Ion Binding Sites of the Ca2+-ATPase: A Molecular Modeling Study

(2011) Maria Musgaard et al.   BIOCHEMISTRY

Activating and Deactivating Roles of Lipid Bilayers on the Ca2+-ATPase/Phospholamban Complex

(2011) Martin Gustavsson et al.   BIOCHEMISTRY

Trinitrophenyl derivatives bind differently from parent adenine nucleotides to Ca2+-ATPase in the absence of Ca2+

(2011) Chikashi Toyoshima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes

(2011) Yonathan Sonntag et al.   Nature Communications

Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase

(2010) Dorthe Mondrup Skytte et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Critical Roles of Hydrophobicity and Orientation of Side Chains for Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase with Thapsigargin and Thapsigargin Analogs

(2010) Anne-Marie L. Winther et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Cholesterol Modulates the Outward Facing Conformation of the Dopamine Transporter and Alters Cocaine Binding

(2010) Weimin C. Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Molecular View of the Cholesterol Condensing Effect in DOPC Lipid Bilayers

(2010) Mohammad Alwarawrah et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

PIP2-Binding Site in Kir Channels: Definition by Multiscale Biomolecular Simulations

(2009) Phillip J. Stansfeld et al.   BIOCHEMISTRY

Combining an Elastic Network With a Coarse-Grained Molecular Force Field: Structure, Dynamics, and Intermolecular Recognition

(2009) Xavier Periole et al.   Journal of Chemical Theory and Computation

Crystal structure of the sodium–potassium pump at 2.4 Å resolution

(2009) Takehiro Shinoda et al.   NATURE

The MARTINI Coarse-Grained Force Field: Extension to Proteins

(2008) Luca Monticelli et al.   Journal of Chemical Theory and Computation

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Coarse-Grained MD Simulations of Membrane Protein-Bilayer Self-Assembly

(2008) Kathryn A. Scott et al.   STRUCTURE

Binding of Anionic Lipids to at Least Three Nonannular Sites on the Potassium Channel KcsA is Required for Channel Opening

(2007) Phedra Marius et al.   BIOPHYSICAL JOURNAL