Article
Microbiology
Myong Chol Kim, Yun Hui Ju, Un A. Hwang, Ping Liu, Sung Ho Pak, Fang Peng
Summary: Strain LRZ-2(T) is a novel member of the suborder Micrococcineae, classified as Pengzhenrongella sicca gen. nov., sp. nov. It possesses unique molecular characteristics and shows significant differences from known bacterial genera.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Afaf Hamame, Reham Magdy Wasfy, Cheikh Ibrahima Lo, Florence Fenollar, Didier Raoult, Pierre-Edouard Fournier, Linda Houhamdi
Summary: Two new bacterial strains, Marseille-P2698(T) and Marseille-P2260(T), were isolated from human stools using the culturomic method. These two strains were fully described using the taxonogenomic approach. Marseille-P2698(T) was identified as a Gram-negative, motile, non-spore-forming, rod-shaped bacterium, while Marseille-P2260(T) was identified as a Gram-positive, motile, spore-forming rod-shaped bacterium.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Ahmed Saeedi, Nicola J. Cummings, Denise McLean, Ian F. Connerton, Phillippa L. Connerton
Summary: ASxL5(T) is a novel Gram-stain negative bacterium with unique growth characteristics and morphology, closely related to members of the Oceanospirillaceae.
SCIENTIFIC REPORTS
(2021)
Article
Environmental Sciences
Ya-Ping Sun, Bei-Bei Wang, Zhang-Ping Wu, Xi-Wen Zheng, Jing Hou, Heng-Lin Cui
Summary: Five novel halophilic archaeal strains were isolated from coastal saline sediments and sea salt in China. They demonstrated typical morphology and growth characteristics and showed high similarities with existing species. However, based on genetic and phylogenetic analyses, it is confirmed that these strains represent five new species. This is the first report of a novel haloarchaeon isolated from a marine intertidal zone.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Microbiology
Janusz Blaszkowski, Khadija Jobim, Piotr Niezgoda, Edward Meller, Ryszard Malinowski, Pawel Milczarski, Szymon Zubek, Franco Magurno, Leonardo Casieri, Wojciech Bierza, Tomasz Blaszkowski, Thomas Crossay, Bruno Tomio Goto
Summary: Examination of fungal specimens collected in the Atlantic rain forest ecosystems of Northeast Brazil revealed many potentially new species of Glomeromycota, with two closely related fungi forming glomerocarps. Phylogenetic analyses indicated that these two fungi represent two divergent undescribed species in the family Glomeraceae, with one placed in the genus Dominikia and the other in a sister clade to the genus Kamienskia.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Lirui Liu, Wen-Cong Huang, Jie Pan, Jiayi Li, Yuhan Huang, Dayu Zou, Huan Du, Yang Liu, Meng Li
Summary: In this study, a novel alphaproteobacterium, FT118(T), was successfully isolated and identified, representing the first cultured member of a previously uncultivated order UBA8317 within Alphaproteobacteria. It is a rare species with a ubiquitous distribution across different habitats. Genomic and metatranscriptomic analyses demonstrate that it is metabolically versatile and active in situ, suggesting its potential role in nutrient cycling despite being scarce. This work not only expands the current phylogeny of isolated Alphaproteobacteria but also provides genomic and culture reference to unravel microbial adaptation strategies in mangrove sediments and possible microbe-environment interactions.
MICROBIOLOGY SPECTRUM
(2023)
Article
Environmental Sciences
Wen-Xing Yu, Qi-Yun Liang, Zong-Jun Du, Da-Shuai Mu
Summary: Biological nitrogen fixation is crucial in the marine nitrogen cycle and affects global marine productivity and carbon fluxes. Two strains isolated from coastal sediment in Weihai, China were analyzed for gene annotation, growth conditions, and 16S rRNA gene sequences. It was revealed that these strains contain nitrogen fixation gene clusters. These novel strains represent new taxa of the Marinilabiliaceae family and have been proposed as Plebeiobacterium marinum gen. nov., sp. nov. and Plebeiobacterium sediminum sp. nov.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Microbiology
Stanislava Kralova, Lenka Davidova-Gerzova, Adam Valcek, Matej Bezdicek, Ivan Rychlik, Veronika Rezacova, Alois Cizek
Summary: This study analyzed three difficult-to-cultivate and strictly anaerobic strains and proposed classifying them into two new genera.
MICROBIOLOGY SPECTRUM
(2022)
Article
Plant Sciences
Andrey A. A. Gontcharov, Arthur Yu. Nikulin, Vyacheslav Yu. Nikulin, Rezeda Z. Z. Allaguvatova, Veronika B. B. Bagmet, Shamil R. R. Abdullin
Summary: Many filamentous and sarcinoid terrestrial or freshwater green algae previously classified in Chlorophyceae are actually members of lineages belonging to Ulvophyceae. A new genus and species of green algae, Ulosarcina terrestrica, was described based on comprehensive studies of previously classified green algae.
Article
Microbiology
Nicolai Kallscheuer, Patrick Rast, Mareike Jogler, Sandra Wiegand, Timo Kohn, Christian Boedeker, Olga Jeske, Anja Heuer, Christian Quast, Frank Oliver Glockner, Manfred Rohde, Christian Jogler
Summary: Waterbodies such as lakes and ponds are fragile environments influenced by human activities. This study found that during a cyanobacterial bloom event in a municipal duck pond, members of the Planctomycetes phylum were significantly enriched in the cyanobacteria-attached fraction. Separate datasets based on isolated DNA and RNA indicated considerable differences in abundance and activity of planctomycetal families during the cyanobacterial bloom.
ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Microbiology
Danillo Oliveira Alvarenga, Ana Paula Dini Andreote, Luis Henrique Zanini Branco, Endrews Delbaje, Renata Beatriz Cruz, Alessandro de Mello Varani, Marli Fatima Fiore
Summary: The genus Nostoc contributes significantly to carbon and nitrogen availability in terrestrial ecosystems and forms symbiotic relationships with non-diazotrophic organisms. A study identified new Nostoc-like cyanobacterial genera and species in South American ecosystems, highlighting the importance of these regions for harboring unknown microbial diversity in the face of increasing anthropogenic threats.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2021)
Article
Microbiology
Sandra Wiegand, Patrick Rast, Nicolai Kallscheuer, Mareike Jogler, Anja Heuer, Christian Boedeker, Olga Jeske, Timo Kohn, John Vollmers, Anne-Kristin Kaster, Christian Quast, Frank Oliver Gloeckner, Manfred Rohde, Christian Jogler
Summary: In recent years, Planctomycetes bacteria have been found to be abundant in many aquatic environments, particularly in epiphytic communities on the surfaces of macroalgae. Analysis showed that Planctomycetes is the most abundant bacterial phylum on the alga Fucus sp., but only represents a minor fraction of bacterial communities on the surfaces of Ulva sp. and Laminaria sp.
Article
Chemistry, Medicinal
Wen-Zhuo Zhu, Shu-Heng Wang, Hui-Min Gao, Ya-Ming Ge, Jun Dai, Xiao-Ling Zhang, Qiao Yang
Summary: In this study, the strain NJES-13(T) from the gut microbiota of the Antarctic emperor penguin was found to have great potential in producing novel bioactive compounds. By using glass bead-enhanced fermentation, the productivity of three bioactive angucycline/angucyclinone derivatives (ADs) was increased. One of the newly identified ADs, 2-hydroxy-frigocyclinone, showed significant cytotoxicity against human-derived cancerous cell lines. The study also proposed the plausible biogenetic pathway of these three bioactive ADs.
Article
Biotechnology & Applied Microbiology
Yi-Fan Liu, Zhong-Lin Liu, Yang-Li Ye, Lei Zhou, Jin-Feng Liu, Shi-Zhong Yang, Ji-Dong Gu, Bo-Zhong Mu
Summary: An anaerobic bacterium, designated as strain L-13(T), was isolated from a methanogenic crude oil-degrading enrichment culture. The bacterium may play a role as both a secondary fermenter and a biomass scavenger.
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
(2021)
Article
Microbiology
Chun-Zhi Jin, Long Jin, Min-Jiao Liu, Jong-Min Lee, Dong-Jin Park, Chang-Jin Kim
Summary: A polyphasic taxonomic study was conducted on an actinobacterial strain AN110305(T) isolated from soil in South Korea. The strain belongs to a novel genus and species named Solihabitans fulvus, and displays characteristics such as Gram-stain positivity, aerobic growth, non-motility, rod shape, and formation of pale-yellow colonies.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2022)
Article
Immunology
Pingping Jia, Yi Zhang, Jian Xu, Mei Zhu, Shize Peng, Yongxin Zhang, Jianyuan Zhao, Xiaoyu Li, Kaixia Mi, Dan Yan, Yucheng Wang, Liyan Yu, Yu Lu, Hanping Shi, Shan Cen
Summary: This study aims to discover new drugs targeting the virulence factor ESX-1 in Mycobacterium tuberculosis. Using a high-throughput screening assay, a compound named IMB-BZ was identified as a specific inhibitor of ESX-1 secretion, showing significant antibacterial and virulence-reducing effects. Importantly, IMB-BZ exhibited low risk of inducing drug resistance in vitro and has the potential to be developed into a novel anti-TB drug.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Environmental Sciences
Tao Zhang, Jun Li, Nengfei Wang, Hao Wang, Liyan Yu
Summary: This study analyzed the diversity and distribution of bacterial communities and antibiotic resistance genes (ARGs) in seawater and sediments of Kongsfjorden in the Arctic through metagenomic analysis. The results showed significant differences in bacterial community compositions and ARG profiles between seawater and sediment samples. Geographic and geochemical factors greatly influenced the bacterial communities and ARG profiles, with Procrustes analysis revealing a significant correlation between the two.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Microbiology
Chenyang He, Jianju Feng, Jing Su, Tao Zhang, Liyan Yu
Summary: This study constructed a supplementary database of MALDI-TOF MS and used it to identify yeast species from polar regions. The results showed that this identification method was accurate and suitable for polar yeasts.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Tao Zhang, Xu Pang, Jianyuan Zhao, Zhe Guo, Wenni He, Guowei Cai, Jing Su, Shan Cen, Liyan Yu
Summary: This study successfully manipulated the fungus Aspergillus sp. CPCC 400735 to activate the downregulated metabolic pathway encoded by the biosynthetic gene cluster asp through overexpression of the transcriptional regulator AspE. 13 asperphenalenone derivatives, including 11 new compounds, were isolated and characterized from the mutant extracts, showing significant anti-influenza A virus effects with IC values of 0.45-2.22 μM. The identification of these compounds sheds light on the biosynthesis of asperphenalenones and could benefit downstream combinatorial biosynthesis studies.
ACS CHEMICAL BIOLOGY
(2022)
Article
Multidisciplinary Sciences
Jianyuan Zhao, Jing Wang, Xu Pang, Zhenlong Liu, Quanjie Li, Dongrong Yi, Yongxin Zhang, Xiaomei Fang, Tao Zhang, Rui Zhou, Zhe Guo, Wancang Liu, Xiaoyu Li, Chen Liang, Tao Deng, Fei Guo, Liyan Yu, Shan Ceri
Summary: Researchers have discovered a compound called APL-16-5 that exhibits antiviral effects against influenza A virus (IAV). APL-16-5 binds to TRIM25 and viral PA protein, leading to the degradation of PA through ubiquitination and proteasome-mediated pathways. This compound shows potent in vivo anti-IAV activity and has the potential to become a new therapeutic option for IAV.
NATURE COMMUNICATIONS
(2022)
Article
Plant Sciences
Xu Pang, Guo-Wei Cai, Meng-Yan Wang, Xiu-Fei Chen, Wen-Ni He, Wu-Li Zhao, Tao Zhang, Li-Yan Yu
Summary: Twenty-two metabolites were isolated from Penicillium sp. CPCC 401423 cultured on rice and their structures were identified. Among them, nine compounds were identified as new. These compounds were tested for their cytotoxic activity against pancreatic carcinoma cells.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
(2023)
Article
Microbiology
Zhi-Lian Gong, Yang Deng, Zhu -Ming Jiang, Lu-Qing Liu, Li-Yan Yu, Jing Su, Yu-Qin Zhang
Summary: A microcystin-degrading bacterium, Shinella lacus sp. nov., was isolated from a fresh water reservoir in Sichuan Province, China. It exhibited optimal growth at 28-32 degrees C and pH 7.0, and contained genes encoding peroxidase, bla carbapenemase, and the key enzyme for microcystin bio degradation. The bacterium showed adaptability to diverse environments.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2022)
Article
Plant Sciences
Bingyuan Zhang, Yan Tang, Zhe Guo, Jun Hu, Qingrong Du, Tao Zhang, Shengjun Dai, Baiping Ma, Liyan Yu, Dewu Zhang
Summary: A new isobenzofuranone derivative and six known compounds were isolated from Arctic fungus Gyoerffyella sp. CPCC 401434, and their structures and absolute configurations were determined. This is the first report of these compounds from the genus Gyoerffyella, and their cytotoxic and antibacterial activities were also studied.
RECORDS OF NATURAL PRODUCTS
(2023)
Correction
Multidisciplinary Sciences
Jianyuan Zhao, Jing Wang, Xu Pang, Zhenlong Liu, Quanjie Li, Dongrong Yi, Yongxin Zhang, Xiaomei Fang, Tao Zhang, Rui Zhou, Zhe Guo, Wancang Liu, Xiaoyu Li, Chen Liang, Tao Deng, Fei Guo, Liyan Yu, Shan Cen
NATURE COMMUNICATIONS
(2023)
Article
Microbiology
Xiufei Chen, Dong Yan, Liyan Yu, Tao Zhang
Summary: In Arctic ecosystems, fungi play a crucial role in soil-plant interactions, nutrient cycling, and carbon transport. However, the mycobiome and its functional role in different habitats of the High Arctic region have not been thoroughly studied. This research aimed to investigate the mycobiome in nine habitats using high-throughput sequencing and found a total of 10,419 detected ASVs. The distribution of the mycobiome was influenced by habitat specificity, and various ecological guilds and growth forms were identified among different habitats.
Article
Microbiology
Tao Zhang, Jianjv Feng, Wenni He, Xiaoting Rong, Hui Lv, Jun Li, Xinxin Li, Hao Wang, Lu Wang, Lixin Zhang, Liyan Yu
Summary: This study reveals the genome and the ability of Desarmillaria tabescens CPCC 401429 fungus to produce diverse sesquiterpene compounds. Through genomic analysis and transcriptomic sequencing, researchers have identified some novel sesquiterpene synthase genes and characterized two of them, confirming the potential of Desarmillaria in generating novel terpenoids.
Article
Environmental Sciences
Tao Zhang, Zhongqiang Ji, Xiufei Chen, Liyan Yu
Summary: This study comprehensively characterized the mycobiome in seawater samples from Kongsfjorden, Svalbard, using shotgun metagenomics. The results showed a diverse mycobiome with significant differences in composition among different water layers. Depth, NO2 , and PO43 were identified as key factors influencing the mycobiome composition.
ENVIRONMENTAL RESEARCH
(2023)
Article
Biotechnology & Applied Microbiology
Ran Zhang, Yujia Wang, Guowei Cai, Juxian Wang, Jianyuan Zhao, Jinglin Bai, Tao Zhang, Shan Cen, Wenni He, Liyan Yu
Summary: Six new phthalide derivatives, namely Verbalide A similar to F (1-6), and one known derivative (7), were isolated from the endophytic fungus Preussia sp. CPCC 400972. The structures of these compounds were determined through comprehensive spectroscopic analyses, including NMR and HRESIMS. Furthermore, compounds 1-7 showed excellent inhibitory effect against influenza A virus.
JOURNAL OF ANTIBIOTICS
(2023)
Article
Chemistry, Organic
Yan Tang, Jing Wang, Zhe Guo, Guowei Gu, Tao Zhang, Shan Cen, Liyan Yu, Shengjun Dai, Dewu Zhang
Summary: A new phenol derivative (1) and seven known phenol analogs (2-8) were isolated from Arctic fungus Phoma muscivora CPCC 401424. Their structures were determined using spectroscopic techniques and comparing with existing data. Compound 1 and 5 exhibited strong anti-influenza A virus activities with IC50 values of 2.20 and 2.17 μM, respectively. Compounds 1, 2, 5, and 7 showed moderate cytotoxic activities against Hela and H460 cancer cell lines.
LETTERS IN ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Guowei Gu, Tao Zhang, Jianyuan Zhao, Wuli Zhao, Yan Tang, Lu Wang, Shan Cen, Liyan Yu, Dewu Zhang
Summary: Three new chromanone dimer derivatives, paecilins F-H (1-3), were isolated from mutant strains of Penicillium oxalicum 114-2. Their structures were elucidated and their configurations were resolved. Compounds 5 and 11 showed significant anti-influenza A virus activities, compounds 8 and 9 exhibited cytotoxic activities against the MIA-PaCa-2 cell line, and compound 10 showed antibacterial activities against Bacillus cereus.
