Article
Engineering, Biomedical
Vittorio Scaravilli, Jacopo Fumagalli, Lorenzo Rosso, Federico Polli, Mauro Panigada, Chiara Abbruzzese, Stefania Crotti, Alfredo Lissoni, Mario Nosotti, Antonio Pesenti, Alberto Zanella, Giacomo Grasselli
Summary: The use of a novel no-heparin management approach during ECMO bridging to lung transplantation (LuTX) can effectively reduce the risk of perioperative bleeding, even in high-risk patients. Prospective studies are needed to further validate the effectiveness of this strategy.
Article
Medicine, General & Internal
Jiwon Ryoo, Jung Huh, Hee Sun Cho, Jin-Jin Kim, Seok Chan Kim, Jongmin Lee
Summary: This study focuses on the diagnosis and treatment of right ventricular (RV) failure in patients undergoing venovenous ECMO, with a case report of successful atrial septostomy as a bridge to lung transplantation in a HSCT recipient.
Article
Critical Care Medicine
Jad Malas, Qiudong Chen, Tao Shen, Dominic Emerson, Tyler Gunn, Dominick Megna, Pedro Catarino, Michael Nurok, Michael Bowdish, Joanna Chikwe, Susan Cheng, Joseph Ebinger, Abirami Kumaresan
Summary: This study aimed to describe the institutional experience with extremely prolonged venovenous extracorporeal membrane oxygenation (ECMO) support for patients with acute respiratory failure. The study found that most patients in this cohort had adult respiratory distress syndrome (ARDS) secondary to COVID-19. Prolonged ECMO support was successful in weaning patients off and enabling their recovery, with a high rate of survival.
CRITICAL CARE MEDICINE
(2023)
Article
Critical Care Medicine
Sung-Min Cho, Joe Canner, Giorgio Caturegli, Chun Woo Choi, Eric Etchill, Katherine Giuliano, Giovanni Chiarini, Kate Calligy, Peter Rycus, Roberto Lorusso, Bo Soo Kim, Marc Sussman, Jose I. Suarez, Romergryko Geocadin, Errol L. Bush, Wendy Ziai, Glenn Whitman
Summary: This study found that approximately 5% of patients receiving venovenous extracorporeal membrane oxygenation experienced acute brain injury, with mortality rates doubling when ischemic or hemorrhagic strokes occurred. Risk factors such as lower pH, hypoxemia, and coagulation disturbances were associated with acute brain injury, highlighting the importance of further research on prevention and management strategies.
CRITICAL CARE MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Deane E. Smith, Stephanie H. Chang, Travis C. Geraci, Les James, Zachary N. Kon, Julius A. Carillo, Marjan Alimi, David Williams, Joshua A. Scheinerman, Robert J. Cerfolio, Eugene A. Grossi, Nader Moazami, Aubrey C. Galloway
Summary: A well-defined patient selection and management strategy of VV-ECMO support in patients with severe COVID-19 resulted in exceptional survival to discharge that was sustained at 1-year after ECMO cannulation.
ANNALS OF THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Kangjoon Kim, Ah Young Leem, Song Yee Kim, Kyung Soo Chung, Moo Suk Park, Young Sam Kim, Jin Gu Lee, Hyo Chae Paik, Su Hwan Lee
Summary: This study investigated the incidence of complications related to ECMO support as a bridge to lung transplantation (BTT) and their association with patient outcomes. The results showed that complications during ECMO support were associated with unfavorable outcomes in lung transplantation.
Article
Cardiac & Cardiovascular Systems
Florian Ponholzer, Stefan Schwarz, Peter Jaksch, Alberto Benazzo, Daria Kifjak, Konrad Hoetzenecker, Thomas Schweiger
Summary: Awake bridging strategies show better outcomes in terms of physical activity and postoperative recovery in lung transplantation patients, especially for those with longer bridging duration.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Review
Medicine, General & Internal
Dubravka Sipus, Kristina Krzelj, Zeljko Duric, Hrvoje Gasparovic, Davor Milicic, Jadranka Separovic Hanzevacki, Daniel Lovric
Summary: Heart transplant remains the gold standard therapy for end-stage heart failure, but using ECMO as a bridge to transplant may be a solution for critically ill patients. However, further research is needed to determine the superiority of direct bridging compared to bridging to durable MCS.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Engineering, Biomedical
Jae Kyeom Sim, Kyeongman Jeon, Gee Young Suh, Suryeun Chung, Yang Hyun Cho
Summary: VV ECMO is effective in supporting patients with respiratory failure, but issues like recirculation and right ventricular failure can arise. OxyRVAD, with its advantages of hemodynamic support and facilitating rehabilitation, can be a better option. Combining VV ECMO with OxyRVAD can overcome these challenges and lead to better outcomes for patients in need of lung transplantation.
Article
Cardiac & Cardiovascular Systems
Ilhan Inci, Jonas Peter Ehrsam, Dirk Van Raemdonck, Laurens Joseph Ceulemans, Thorsten Krueger, Angela Koutsokera, Marco Schiavon, Eleonora Faccioli, Mario Nosotti, Lorenzo Rosso, Frank D'Ovidio, Miguel Leiva-Juarez, Clemens Aigner, Alexis Slama, Waleed Saleh, Khaled Manaa Alkattan, Pascal Alexandre Thomas, Geoffrey Brioude, Alberto Benazzo, Konrad Hoetzenecker
Summary: This study investigated the outcomes of recipients bridged to a first-time retransplantation (ReTx) by extracorporeal life support (ECLS). The results showed that the overall survival of the ECLS-ReTx group was significantly worse compared to the regular-ReTx and index-Tx groups. Risk factors such as recipient age, intertransplant interval, primary graft dysfunction as transplant indication, and type of ECLS were identified as significant factors affecting mortality in ECLS-ReTx recipients.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Critical Care Medicine
Akram Zaaqoq, Matthew Griffee, Thu-Lan Kelly, Jonathon Fanning, Silver Heinsar, Jacky Suen, Silvia Mariani, Gianluigi Li Bassi, Jeffrey Jacobs, Nicole White, John Fraser, Roberto Lorusso, Giles Peek, Sung-Min Cho
Summary: This study aims to characterize the prevalence and risk factors of stroke secondary to COVID-19 in patients on venovenous ECMO. The results showed that obesity and pre-ECMO vasopressor use were associated with an increased risk of stroke. In addition, stroke patients had a more significant relative decrease in Paco(2) and relative increase in Pao(2) within 48 hours after ECMO initiation compared to non-stroke patients, and they also had a higher in-hospital mortality rate.
CRITICAL CARE MEDICINE
(2023)
Editorial Material
Infectious Diseases
Yoshihiko Takahashi, Shu Utsumi, Gaku Sugiura, Kenji Fujizuka, Hiroyuki Suzuki, Mitsunobu Nakamura
Summary: We present the first case of airway obstruction caused by toxin-producing Corynebacterium ulcerans, which was successfully managed with venovenous extracorporeal membrane oxygenation (V-V ECMO). The patient, a 73-year-old woman living with companion animals, was intubated for pneumonia and treated with an antimicrobial agent. Corynebacterium species were found in the sputum and considered commensal bacteria. However, central airway obstruction due to pseudomembrane formation occurred, leading to the initiation of V-V ECMO. Mass spectrometry confirmed the presence of C. ulcerans, and antitoxin treatment allowed successful weaning from V-V ECMO. Therefore, C. ulcerans pneumonia should be suspected in patients with respiratory failure and pseudomembrane formation, and treatment strategies including V-V ECMO should be considered.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Critical Care Medicine
Nina Buchtele, Christian Schoergenhofer, Michael Schwameis, Bernd Jilma, Peter Schellongowski, Harald Herkner, Katharina Riss, Monika Schmid, Alexander Hermann, Oliver Robak, Bernhard Nagler, Ludwig Traby, Andja Bojic, Thomas Staudinger
Summary: This study investigated the safety and efficacy of PGE(1) in adults receiving venovenous extracorporeal membrane oxygenation (ECMO). The results showed that PGE(1) can reduce thromboembolic events and clinically overt bleeding events, as well as prolong the time without bleeding and thromboembolism.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Medicine, General & Internal
Ting Chen, Li Yao, Xiaoqin Fan, Chunyan Zhu
Summary: This case involved a 43-year-old male with advanced silicosis who developed a massive hollow catheter thrombus during lung transplantation. Anticoagulant therapy with heparin did not affect the thrombus size, leading to the patient's death from infection and multiple organ failure. It is important to monitor and manage thrombotic complications during lung transplantation under ECMO.
Article
Medicine, General & Internal
Holger Thiele, Uwe Zeymer, Ibrahim Akin, Michael Behnes, Tienush Rassaf, Amir Abbas Mahabadi, Ralf Lehmann, Ingo Eitel, Tobias Graf, Tim Seidler, Andreas Schuster, Carsten Skurk, Daniel Duerschmied, Peter Clemmensen, Marcus Hennersdorf, Stephan Fichtlscherer, Ingo Voigt, Melchior Seyfarth, Stefan John, Sebastian Ewen, Axel Linke, Eike Tigges, Peter Nordbeck, Leonhard Bruch, Christian Jung, Jutta Franz, Philipp Lauten, Tomaz Goslar, Hans-Josef Feistritzer, Janine Poess, Eva Kirchhof, Taoufik Ouarrak, Steffen Schneider, Steffen Desch, Anne Freund, ECLS-SHOCK Investigators
Summary: In patients with acute myocardial infarction complicated by cardiogenic shock, early extracorporeal life support (ECLS) combined with standard medical treatment did not reduce mortality.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Engineering, Biomedical
Jay Menaker, Ronald P. Rabinowitz, Ali Tabatabai, Ronald B. Tesoriero, Katelyn Dolly, Christopher Cornachione, Edward Stene, Jessica Buchner, Joseph Kufera, Zachary N. Kon, Kristopher B. Deatrick, Daniel L. Herr, James V. O'Connor, Thomas M. Scalea
Article
Nutrition & Dietetics
Stacy Pelekhaty, Samuel M. Galvagno, Eric Hochberg, Daniel L. Herr, James H. Lantry, Zachary N. Kon, Kristopher B. Deatrick, Jay Menaker
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2020)
Article
Anesthesiology
Michael A. Mazzeffi, Kenichi Tanaka, Alia Roberts, Raymond Rector, Jay Menaker, Zachary Kon, Kristopher B. Deatrick, David Kaczorowski, Bartley Griffith, Daniel Herr
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2019)
Article
Cardiac & Cardiovascular Systems
Chetan Pasrija, Kristen M. Mackowick, Maxwell Raithel, Douglas Tran, Francesca M. Boulos, Kristopher B. Deatrick, Michael A. Mazzeffi, Raymond Rector, Si M. Pham, Bartley P. Griffith, Daniel L. Herr, Zachary N. Kon
ANNALS OF THORACIC SURGERY
(2019)
Article
Engineering, Biomedical
Michael Mazzeffi, Zachary Kon, Jay Menaker, Daniel M. Johnson, Orlando Parise, Sandro Gelsomino, Roberto Lorusso, Daniel Herr
Article
Anesthesiology
Michael Mazzeffi, Shaheer Hasan, Ezeldeen Abuelkasem, Michael Meyer, Kristopher Deatrick, Bradley Taylor, Zachary Kon, Daniel Herr, Kenichi Tanaka
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2019)
Article
Cardiac & Cardiovascular Systems
Jay Menaker, Samuel Galvagno, Ronald Rabinowitz, Vesselin Penchev, Allison Hollis, Zachary Kon, Kristopher Deatrick, Anthony Amoroso, Daniel Herr, Michael Mazzeffi
Article
Nutrition & Dietetics
Stacy L. Pelekhaty, Samuel M. Galvagno, James H. Lantry, Katelyn N. Dolly, Daniel L. Herr, Zachary N. Kon, Kristopher B. Deatrick, Christopher R. Cornachione, Thomas M. Scalea, Jay Menaker
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2020)
Article
Cardiac & Cardiovascular Systems
Kristopher B. Deatrick, Samuel M. Galvagno, Michael A. Mazzeffi, David J. Kaczoroswki, Daniel L. Herr, Raymond Rector, Eric Hochberg, Ronald P. Rabinowitz, Thomas M. Scalea, Jay Menaker
Article
Cardiac & Cardiovascular Systems
Alison Grazioli, Sanjeev R. Shah, Joseph Rabin, Rashmikant Shah, Ronson J. Madathil, Joshua D. King, Laura DiChiacchio, Raymond P. Rector, Kristopher B. Deatrick, Zhongjun J. Wu, Daniel L. Herr
Article
Toxicology
Lindsay Weiner, Michael A. Mazzeffi, Elizabeth Q. Hines, David Gordon, Daniel L. Herr, Hong K. Kim
CLINICAL TOXICOLOGY
(2020)
Article
Critical Care Medicine
Eric Hoste, Azra Bihorac, Ali Al-Khafaji, Luis M. Ortega, Marlies Ostermann, Michael Haase, Kai Zacharowski, Richard Wunderink, Michael Heung, Matthew Lissauer, Wesley H. Self, Jay L. Koyner, Patrick M. Honore, John R. Prowle, Michael Joannidis, Lui G. Forni, J. Patrick Kampf, Paul McPherson, John A. Kellum, Lakhmir S. Chawla
INTENSIVE CARE MEDICINE
(2020)
Article
Anesthesiology
Matthew Li, Michael A. Mazzeffi, James S. Gammie, Mary Banoub, Yogitha Pazhani, Daniel Herr, Ronson Madathil, Sheelagh Pousatis, Allison Bathula
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2020)
Article
Cardiac & Cardiovascular Systems
Laura DiChiacchio, Francesca M. Boulos, Francis Brigante, Maxwell Raithel, Aakash Shah, Chetan Pasrija, Kristen Mackowick, Jay Menaker, Michael Mazzeffi, Daniel Herr, Zachary N. Kon, Kristopher B. Deatrick
Article
Cardiac & Cardiovascular Systems
Ali Tabatabai, Jay Menaker, Edward Stene, Joseph A. Kufera, Ronald P. Rabinowitz, Zachary Kon, Daniel L. Herr, Thomas M. Scalea
Article
Cardiac & Cardiovascular Systems
Soh Hosoba, Toshiaki Ito, Makoto Mori, Riku Kato, Koh Kajiyama, Shogo Maeda, Yuji Nakai, Yoshihiro Morishita
Summary: This study describes the approach and perioperative outcomes of totally endoscopic isolated and concomitant surgical aortic valve replacement (AVR) using various valve types. The results demonstrate that endoscopic AVR can safely address concomitant valve diseases.
ANNALS OF THORACIC SURGERY
(2024)
