Journal
INTERNATIONAL JOURNAL OF STD & AIDS
Volume 21, Issue 3, Pages 207-208Publisher
ROYAL SOC MEDICINE PRESS LTD
DOI: 10.1258/ijsa.2009.009331
Keywords
sexually transmitted infections; HIV shedding; seminal plasma
Categories
Funding
- California HIV Research Program (CHRP) IDEA [ID03-REI-040, CCTG-CH05-SD-607-005]
- NIH [GCRC M01-RR00425, AI069424, MH083552, AI077304]
- UCSD Center for AIDS Research [AI36214]
- Research Center for AIDS
- San Diego Veterans Affairs Healthcare System [10-92-035]
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The effect of asymptomatic sexually transmitted urethral infections on human immunodeficiency virus (HIV) RNA viral load in semen is poorly defined. We studied five such patients. Those on antiretrovirals (n = 2) had lower seminal plasma viral loads (SPVL) (2.11 and 1.98 log(10) copies/mL) than those not on antiretrovirals (n = 3) (2.27-3.78 log(10) copies/mL). One patient who was not taking antiretrovirals had a 94% decline in SPVL after treatment of asymptomatic Chlamydia trachomatis urethritis, suggesting that asymptomatic infection may be a co-factor for HIV transmission.
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