Article
Medicine, General & Internal
Haoyu Weng, Fan Yang, Long Zhang, Han Jin, Shengcong Liu, Fangfang Fan, Zhihao Liu, Xizi Zheng, Hongyu Yang, Yuxi Li, Tieci Yi, Haichao Li, Yan Zhang, Jianping Li, Tieci Yi, Haichao Li, Yan Zhang, Jianping Li
Summary: This study found that elevated levels of cardiac troponin I and N-terminal pro-B-type natriuretic peptide in COVID-19 patients are associated with an increased risk of death, with even higher risk when both markers are elevated. Therefore, monitoring these cardiac injury parameters may help to identify patients at a higher risk of mortality in the later course of COVID-19.
JOURNAL OF TRANSLATIONAL INTERNAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Giuseppe Vergaro, Francesco Gentile, Alberto Aimo, James L. Januzzi, A. Mark Richards, Carolyn S. P. Lam, Rudolf A. Boer, Laura M. G. Meems, Roberto Latini, Lidia Staszewsky, Inder S. Anand, Jay N. Cohn, Thor Ueland, Lars Gullestad, Pal Aukrust, Hans-Peter Brunner-La Rocca, Antoni Bayes-Genis, Josep Lupon, Akiomi Yoshihisa, Yasuchika Takeishi, Michael Egstrup, Ida Gustafsson, Hanna K. Gaggin, Kai M. Eggers, Kurt Huber, Greg D. Gamble, Lieng H. Ling, Kui Toh Gerard Leong, Poh Shuah Daniel Yeo, Hean Yee Ong, Fazlur Jaufeerally, Tze P. Ng, Richard Troughton, Robert N. Doughty, Gerry Devlin, Mayanna Lund, Alberto Giannoni, Claudio Passino, Michele Emdin
Summary: This study aims to investigate the plasma concentrations, determinants, and optimal prognostic cut-offs of soluble suppression of tumorigenesis-2 (sST2), high-sensitivity cardiac troponin T (hs-cTnT), and N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients with chronic heart failure (HF). The results showed that women had lower concentrations of sST2 and hs-cTnT, while the NT-proBNP concentrations remained similar. The use of sex-specific cut-offs improved risk prediction, especially for hs-cTnT, and allowed for better risk reclassification.
Article
Chemistry, Analytical
Maria Antonio, Rui Vitorino, Ana L. Daniel-da-Silva
Summary: We developed a rapid and straightforward localized surface plasmon resonance (LSPR)-based assay for detecting NT-proBNP in urine using citrate-capped gold nanoparticles and an aptamer specific for NT-proBNP. The assay showed linear correlation between NT-proBNP concentration and aggregation ratio, with a detection range of 0.566-8 μg.L-1 and a limit of detection (LOD) of 0.303 μg.L-1. However, the presence of sulfur-containing proteins hindered detection in saliva and fetal bovine serum. Nevertheless, the assay successfully detected NT-proBNP in diluted urine, showing potential clinical relevance. The recovery percentages ranged from 92.3 to 116.3%.
Article
Cardiac & Cardiovascular Systems
William R. Miranda, C. Charles Jain, Barry A. Borlaug, Allan S. Jaffe, Heidi M. Connolly, Luke J. Burchill, Alexander C. Egbe
Summary: This study found that resting and exercise pressures in the heart and pulmonary artery were correlated with exercise capacity and NT-proBNP levels in adults post-Fontan. Additionally, exercise cardiac catheterization may provide prognostic information.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Paul W. Armstrong, Yinggan Zheng, Richard W. Troughton, Lars H. Lund, Jian Zhang, Carolyn S. P. Lam, Cynthia M. Westerhout, Robert O. Blaustein, Javed Butler, Adrian F. Hernandez, Lothar Roessig, Christopher M. O'Connor, Adrian A. Voors, Justin A. Ezekowitz
Summary: This study assessed the effect of vericiguat on changes in NT-proBNP levels and its relationship with clinical outcomes. The results showed that vericiguat treatment led to a significant decline in NT-proBNP levels, which was associated with a relative improvement in the primary outcome of cardiovascular death or heart failure hospitalization.
JACC-HEART FAILURE
(2022)
Article
Cardiac & Cardiovascular Systems
Stefano Ciardullo, Federico Rea, Rosa Cannistraci, Emanuele Muraca, Silvia Perra, Francesca Zerbini, Andrea Mortara, Gianluca Perseghin
Summary: This study found that elevated NT-ProBNP levels were independently associated with all-cause and cardiovascular mortality in the general population, aiding in the identification of high-risk patients.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Rafel Cirer-Sastre, Romario Jimenez-Gaytan, Luis Enrique Carranza-Garcia, Keith George, Fred S. Apple, Ricardo Navarro-Orocio, Ricardo Lopez-Garcia, Joaquin Reverter-Masia, Carmen Mayolas-Pi, Pedro Gualberto Morales-Corral, Alejandro Legaz-Arrese
Summary: This cross-sectional observational study found that post-exercise elevations of cTnT and cTnI may differ, with cTnT peaking earlier at 2.9 hours post-exercise and cTnI peaking later at 4.5 hours post-exercise. There was no significant effect of sex and maturational status on cTn responses.
Article
Medical Laboratory Technology
Ling Li, Alexander G. Semenov, Evgeniya E. Feygina, Chenchen Yang, Nan Wang, Chao Chen, Xinghai Hu, Xiaoqin Ni, Zhenlu Zhang
Summary: The study compared the diagnostic accuracy of two NT-proBNP assays and found that the clinical value of total NT-proBNP for HF diagnosis was similar to the non-glycosylated subfraction of NT-proBNP. The lower percentage of non-glycosylated NT-proBNP to total NT-proBNP in non-HF patients suggests that total NT-proBNP might be more sensitive in individuals without current or prior symptoms of HF.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Medicine, General & Internal
Chin-Shern Lau, Ya Li Liang, Soon Kieng Phua, Gillian Murtagh, Imo E. Hoefer, Ron H. Stokwielder, Milica Kosevich, Jennifer Yen, Jaganathan Sickan, Christos Varounis, Tar-Choon Aw
Summary: This study evaluated the performance of the Abbott NT-proBNP assay compared to the Roche NT-proBNP immunoassay at two sites. Precision, linearity, and sensitivity studies were conducted, and a regression analysis was performed. The results showed excellent agreement between the two assays, with slight bias in the Roche assay. The age groups recommended for acute heart failure diagnosis by ESC/AHA were also applicable to the Abbott assay.
Article
Oncology
Jozef Chovanec Jr, Jozef Chovanec, Michal Chovanec, Michal Mego
Summary: Currently, it is known that cancer cells can produce natriuretic peptides. The synthesis of N-terminal pro B-type natriuretic peptide (NT-proBNP) may be a response to the activity of proinflammatory cytokines. NT-proBNP is also a marker for myocardial damage caused by anthracycline chemotherapy in cancer patients.
Article
Medical Laboratory Technology
Kwaku D. Tawiah, Caroline E. Franks, Jessica Tang, Avihu Gazit, Dennis J. Dietzen, Christopher W. Farnsworth
Summary: This study investigated the concordance and correlation between BNP and NT-proBNP in pediatric patients. The results showed a positive correlation and moderate concordance between BNP and NT-proBNP. Age group and cardiac pathology had some impact on the concordance.
CLINICAL BIOCHEMISTRY
(2022)
Article
Medical Laboratory Technology
Nicole Mueller, Eva Bayer, Christine Bernhardt, Johannes Breuer, Noa J. Freudenthal
Summary: Urinary NT-proBNP has been shown to be a useful diagnostic tool for children with congenital heart disease, with the ability to differentiate between relevant and nonrelevant cases. It may also be valuable as a follow-up parameter for children after corrective surgery.
CLINICA CHIMICA ACTA
(2022)
Article
Oncology
Sonja Levy, Aoife B. Kilgallen, Catharina M. Korse, Marish I. F. J. Oerlemans, Joost P. G. Sluijter, Linda W. van Laake, Gerlof D. Valk, Margot E. T. Tesselaar
Summary: This study validated NT-proBNP as the superior biomarker for CHD. Patients with elevated serotonin levels and NT-proBNP levels between 6.5 and 27 pmol/L, and specifically >27 pmol/L, should be monitored closely for the development of CHD.
Article
Pediatrics
Lukas Schroeder, Manuel Kuelshammer, Ramona Dolscheid-Pommerich, Stefan Holdenrieder, Andreas Mueller, Florian Kipfmueller
Summary: The present study aimed to investigate the suitability of NT-proBNP as a biomarker for predicting extubation failure in critically ill neonates with pulmonary hypertension or ventricular dysfunction. The results showed that there were differences in the absolute values of NT-proBNP before and after extubation, and the Zlog transformation of NT-proBNP could better predict the occurrence of extubation failure.
PEDIATRIC PULMONOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Yi Peng, Nikhil Raj, Juliette W. Strasser, Richard M. Crooks
Summary: This study reports the use of silver nanodisks (AgNDs) as electrochemical labels for the detection of the heart failure biomarker NT-proBNP. The AgNDs labels showed superior performance compared to other silver nanocubes and nanospheres, with a detection range that fully overlaps the risk stratification range for heart failure.
Article
Cardiac & Cardiovascular Systems
Bernard Belhassen, Mikael Laredo, Rob W. Roudijk, Giovanni Peretto, Guy Zahavi, Srijita Sen-Chowdhry, Nicolas Badenco, Anneline S. J. M. Te Riele, Simone Sala, Guillaume Duthoit, J. Peter van Tintelen, Gabriele Paglino, Jean-Marc Sellal, Alessio Gasperetti, Elena Arbelo, Antoine Andorin, Sandro Ninni, Anne Rollin, Petr Peichl, Xavier Waintraub, Laurens P. Bosman, Bertrand Pierre, Eyal Nof, Chris Miles, Jacob Tfelt-Hansen, Alexandros Protonotarios, Carla Giustetto, Frederic Sacher, Jean-Sylvain Hermida, Stepan Havranek, Leonardo Calo, Ruben Casado-Arroyo, Giulio Conte, Konstantinos P. Letsas, Esther Zorio, Francisco J. Bermudez-Jimenez, Elijah R. Behr, Roy Beinart, Laurent Fauchier, Josef Kautzner, Philippe Maury, Dominique Lacroix, Vincent Probst, Josep Brugada, Firat Duru, Christian de Chillou, Paolo Della Bella, Estelle Gandjbakhch, Richard Hauer, Anat Milman
Summary: The study found that RBBB-VT accounts for a significant proportion of sustained VTs in ACM patients. Sex and type of pathogenic mutations are associated with VT type, with female sex associated with LBBB + RBBB-VT and DSP mutation associated with RBBB-VT.
Article
Cardiac & Cardiovascular Systems
Natasja M. S. de Groot, Dipen Shah, Patrick M. Boyle, Elad Anter, Gari D. Clifford, Isabel Deisenhofer, Thomas Deneke, Pascal van Dessel, Olaf Doessel, Polychronis Dilaveris, Frank R. Heinzel, Suraj Kapa, Pier D. Lambiase, Joost Lumens, Pyotr G. Platonov, Tachapong Ngarmukos, Juan Pablo Martinez, Alejandro Olaya Sanchez, Yoshihide Takahashi, Bruno P. Valdigem, Alle-Jan Van der Veen, Kevin Vernooy, Ruben Casado-Arroyo, Tom De Potter, Borislav Dinov, Jedrzej Kosiuk, Dominik Linz, Lis Neubeck, Emma Svennberg, Young-Hoon Kim, Elaine Wan, Nestor Lopez-Cabanillas, Emanuela T. Locati, Peter Macfarlane
Summary: This article provides a critical appraisal of signal recording and processing technologies applied for atrial fibrillation mapping and detection. Current technologies have limitations and are mainly restricted to specific applications. It highlights the importance of improving signal processing and anticipates future enhancements and automation.
Article
Medicine, General & Internal
Shingo Maeda, Masahiko Goya, Yasuhiro Shirai, Atsuhiko Yagishita, Susumu Tao, Jackson Jeikai Liang, Ruben Casado Arroyo, Yoshihide Takahashi, Mihoko Kawabata, Tetsuo Sasano, Kenzo Hirao
Summary: This study aimed to identify novel predictors of effective atrial anti-tachycardia pacing (A-ATP) for terminating atrial fibrillation (AF) in patients undergoing catheter ablation. The results showed that simultaneous biatrial A-ATP from the right atrium (RA) and coronary sinus (CS) could terminate AF in patients with paroxysmal AF. The predictors for successful termination included longer AF cycle length and higher AF stability.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biotechnology & Applied Microbiology
Rafel Cirer-Sastre, Romario Jimenez-Gaytan, Luis Enrique Carranza-Garcia, Keith George, Fred S. Apple, Ricardo Navarro-Orocio, Ricardo Lopez-Garcia, Joaquin Reverter-Masia, Carmen Mayolas-Pi, Pedro Gualberto Morales-Corral, Alejandro Legaz-Arrese
Summary: This cross-sectional observational study found that post-exercise elevations of cTnT and cTnI may differ, with cTnT peaking earlier at 2.9 hours post-exercise and cTnI peaking later at 4.5 hours post-exercise. There was no significant effect of sex and maturational status on cTn responses.
Review
Cardiac & Cardiovascular Systems
Giuseppe Boriani, Marco Vitolo, Emma Svennberg, Ruben Casado-Arroyo, Jose L. Merino, Christophe Leclercq
Summary: There is a growing emphasis on demonstrating the value of medical interventions and technologies. New approaches such as outcome-based contracts and risk-sharing agreements have been proposed to link coverage or payment for innovative treatments to specific clinical outcomes. This is particularly relevant in the field of electrophysiology, where risk-sharing agreements can demonstrate the value of innovative technologies and reduce financial risk for hospitals. Physicians involved in arrhythmia management and invasive electrophysiology should be prepared to participate in evaluating technology performance and patient outcomes.
Article
Sport Sciences
J. O. Lagunes-Carrasco, R. Lopez-Garcia, L. E. Carranza-Garcia, R. Navarro-Orocio, E. Ramirez-Lopez
Summary: The aim of this study was to describe the anthropometric profile and somatotype of Mexican college football players, and examine them based on their playing position. The results showed that linemen had higher body weight and body composition compared to other positions, although they had relatively high musculoskeletal development, they did not meet the standards of professional and university levels, and were found to have problems of overweight and obesity.
REVISTA IBEROAMERICANA DE CIENCIAS DE LA ACTIVIDAD FISICA Y EL DEPORTE
(2022)
Article
Sport Sciences
C. Y. Rojas-Aboite, P. L. Hernandez-Cortes, M. C. Enriquez-Reyna, L. E. Carranza-Garcia, R. Navarro-Orocio, D. Carranza-Bautista
Summary: This study described the cardiovascular risk and level of physical activity among working adults in a health institution, and explored the association between these variables. The findings revealed that age, hypertension, smoking, diabetes mellitus, and overweight/obesity were the most prevalent cardiovascular risk factors, all of which were strongly associated with physical inactivity.
REVISTA IBEROAMERICANA DE CIENCIAS DE LA ACTIVIDAD FISICA Y EL DEPORTE
(2022)
Review
Cardiac & Cardiovascular Systems
Zbigniew Kalarus, Georges H. Mairesse, Adam Sokal, Giuseppe Boriani, Beata Sredniawa, Ruben Casado Arroyo, Rolf Wachter, Gerrit Frommeyer, Vassil Traykov, Nikolaos Dagres, Gregory Y. H. Lip, Lucas Boersma, Petr Peichl, Dobromir Dobrev, Alan Bulava, Carina Blomstrom-Lundqvist, Natasja M. S. de Groot, Renate Schnabel, Frank Heinzel, Isabelle C. Van Gelder, Corrado Carbuccichio, Dipen Shah, Lars Eckardt
Editorial Material
Cardiac & Cardiovascular Systems
Ruben Casado-Arroyo, Moises Levinstein
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Article
Health Care Sciences & Services
Cecile Maeyens, Pierre Nokerman, Ruben Casado-Arroyo, Juan-Pablo Abugattas De Torres, Brenton Alexander, Edgard Engelman, Denis Schmartz, Turgay Tuna
Summary: This study measured the displacement of cardiac structures in 21 patients undergoing atrial fibrillation ablation during high-frequency jet ventilation (HFJV) and normal mechanical ventilation. The results showed that the displacement of cardiac structures was significantly smaller during HFJV compared to normal mechanical ventilation.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Sport Sciences
L. E. Carranza-Garcia, R. Lopez-Garcia, J. O. Lagunes-Carrasco, P. L. Hernandez-Cortes, M. C. Enriquez-Reyna, R. Navarro-Orocio
Summary: This article reviews conservative treatments for flat foot, including strengthening exercises, stretching, and orthotics. More research is needed to evaluate the short- and long-term effects of these treatments.
REVISTA IBEROAMERICANA DE CIENCIAS DE LA ACTIVIDAD FISICA Y EL DEPORTE
(2022)
Review
Orthopedics
Victor M. Salinas-Torres, Rafael A. Salinas-Torres, Luis E. Carranza-Garcia, Jesus Herrera-Orozco, Jose L. Tristan-Rodriguez
JOURNAL OF FOOT & ANKLE SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Giuseppe Boriani, Jacopo F. Imberti, Francisco Leyva, Ruben Casado-Arroyo, Julian Chun, Frieder Braunschweig, Maura M. Zylla, David Duncker, Michal M. Farkowski, Helmut Puererfellner, Jose L. Merino
Summary: There is wide variability in the length of stay for elective EP procedures, with some procedures having disproportionately long stays compared to their complexity. Reimbursement and bed availability did not consistently impact the organization of elective procedures.
Article
Hospitality, Leisure, Sport & Tourism
Ricardo Lopez Garcia, Jose Omar Lagunes Carrasco, Luis Enrique Carranza Garcia, Ricardo Navarro-Orocio, Andres Aquilino Castro Zamora
Summary: The aim of this study was to investigate the relationship between bone diameters, BMI, and fat percentage in Mexican university athletes. The results showed that individuals with higher BMI and fat percentage had larger bone diameters.
RETOS-NUEVAS TENDENCIAS EN EDUCACION FISICA DEPORTE Y RECREACION
(2022)
Article
Hospitality, Leisure, Sport & Tourism
Jose Omar Lagunes-Carrasco, Luis Enrique Carranza-Garcia, Ricardo Lopez-Garcia, Alejandro Legaz-Arrese, Ricardo Navarro-Orocio, Erik Ramirez-Lopez
Summary: The study aimed to develop a new anthropometric regression equation for predicting body fat percentage in American football players. Through evaluation and research on body composition of 90 players, a new prediction equation was established.
RETOS-NUEVAS TENDENCIAS EN EDUCACION FISICA DEPORTE Y RECREACION
(2022)