Hypoxia-Targeting Fluorescent Nanobodies for Optical Molecular Imaging of Pre-Invasive Breast Cancer

Imaging tumour hypoxia with positron emission tomography

(2014) I N Fleming et al.   BRITISH JOURNAL OF CANCER

A novel VHH nanobody against the active site (the CA domain) of tumor-associated, carbonic anhydrase isoform IX and its usefulness for cancer diagnosis

(2013) Fatemeh Araste et al.   BIOTECHNOLOGY LETTERS

Molecular imaging with a fluorescent antibody targeting carbonic anhydrase IX can successfully detect hypoxic ductal carcinoma in situ of the breast

(2013) Aram S. A. van Brussel et al.   BREAST CANCER RESEARCH AND TREATMENT

Rapid optical imaging of human breast tumour xenografts using anti-HER2 VHHs site-directly conjugated to IRDye 800CW for image-guided surgery

(2013) Marta Kijanka et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Intraoperative fluorescence delineation of head and neck cancer with a fluorescent Anti-epidermal growth factor receptor nanobody

(2013) P.B.A.A. van Driel et al.   INTERNATIONAL JOURNAL OF CANCER

Near Infrared Optical Visualization of Epidermal Growth Factor Receptors Levels in COLO205 Colorectal Cell Line, Orthotopic Tumor in Mice and Human Biopsies

(2013) Gadi Cohen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthesis, Preclinical Validation, Dosimetry, and Toxicity of 68Ga-NOTA-Anti-HER2 Nanobodies for iPET Imaging of HER2 Receptor Expression in Cancer

(2013) C. Xavier et al.   JOURNAL OF NUCLEAR MEDICINE

Immunophenotyping invasive breast cancer: paving the road for molecular imaging

(2012) Jeroen F Vermeulen et al.   BMC CANCER

Nanobody-Based Targeting of the Macrophage Mannose Receptor for EffectiveIn VivoImaging of Tumor-Associated Macrophages

(2012) Kiavash Movahedi et al.   CANCER RESEARCH

In Vivo Imaging and Quantification of Carbonic Anhydrase IX Expression as an Endogenous Biomarker of Tumor Hypoxia

(2012) Bagna Bao et al.   PLoS One

A novel method to quantify IRDye800CW fluorescent antibody probes ex vivo in tissue distribution studies

(2012) Sabrina Oliveira et al.   EJNMMI Research

Noninvasive Detection of Breast Cancer Lymph Node Metastasis Using Carbonic Anhydrases IX and XII Targeted Imaging Probes

(2011) N. K. Tafreshi et al.   CLINICAL CANCER RESEARCH

Facile labelling of an anti-epidermal growth factor receptor Nanobody with 68Ga via a novel bifunctional desferal chelate for immuno-PET

(2011) Maria J. W. D. Vosjan et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Intraoperative Near-Infrared Fluorescence Tumor Imaging with Vascular Endothelial Growth Factor and Human Epidermal Growth Factor Receptor 2 Targeting Antibodies

(2011) A. G. T. Terwisscha van Scheltinga et al.   JOURNAL OF NUCLEAR MEDICINE

Generation of a Family-specific Phage Library of Llama Single Chain Antibody Fragments That Neutralize HIV-1

(2010) Willie W. L. Koh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia and metabolic phenotypes during breast carcinogenesis: expression of HIF-1α, GLUT1, and CAIX

(2010) Chi-Long Chen et al.   VIRCHOWS ARCHIV

Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target

(2009) Giuseppina De Simone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Molecular imaging of breast cancer

(2009) T.H. Oude Munnink et al.   BREAST

Real-time intraoperative fluorescence imaging system using light-absorption correction

(2009) George Themelis et al.   JOURNAL OF BIOMEDICAL OPTICS

A modeling analysis of the effects of molecular size and binding affinity on tumor targeting

(2009) M. M. Schmidt et al.   MOLECULAR CANCER THERAPEUTICS

A Novel Fluorescent Imaging Agent for Diffuse Optical Tomography of the Breast: First Clinical Experience in Patients

(2009) Stephanie van de Ven et al.   MOLECULAR IMAGING AND BIOLOGY

Comparative pharmacokinetics, biodistribution, metabolism and hypoxia-dependent uptake of [18F]-EF3 and [18F]-MISO in rodent tumor models

(2008) Pierre Mahy et al.   RADIOTHERAPY AND ONCOLOGY