Polarity and cell division orientation in the cleavage embryo: from worm to human

Cortical Tension Allocates the First Inner Cells of the Mammalian Embryo

(2015) Chaminda R. Samarage et al.   DEVELOPMENTAL CELL

Pulsatile cell-autonomous contractility drives compaction in the mouse embryo

(2015) Jean-Léon Maître et al.   NATURE CELL BIOLOGY

An instructive role for C. elegans E-cadherin in translating cell contact cues into cortical polarity

(2015) Diana Klompstra et al.   NATURE CELL BIOLOGY

Initiation of Hippo signaling is linked to polarity rather than to cell position in the pre-implantation mouse embryo

(2014) Shihadeh Anani et al.   DEVELOPMENT

Inhibition of RHO–ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst

(2014) Kanako Kono et al.   DEVELOPMENTAL BIOLOGY

The basal position of nuclei is one pre-requisite for asymmetric cell divisions in the early mouse embryo

(2014) Anna Ajduk et al.   DEVELOPMENTAL BIOLOGY

Coupling of Rotational Cortical Flow, Asymmetric Midbody Positioning, and Spindle Rotation Mediates Dorsoventral Axis Formation in C. elegans

(2014) Deepika Singh et al.   DEVELOPMENTAL CELL

Getting to know your neighbor: Cell polarization in early embryos

(2014) Jeremy Nance   JOURNAL OF CELL BIOLOGY

HIPPO Pathway Members Restrict SOX2 to the Inner Cell Mass Where It Promotes ICM Fates in the Mouse Blastocyst

(2014) Eryn Wicklow et al.   PLoS Genetics

The Hippo Pathway Member Nf2 Is Required for Inner Cell Mass Specification

(2013) Katie Cockburn et al.   CURRENT BIOLOGY

Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos

(2013) Yoshikazu Hirate et al.   CURRENT BIOLOGY

PAR-2, LGL-1 and the CDC-42 GAP CHIN-1 act in distinct pathways to maintain polarity in the C. elegans embryo

(2013) A. Beatty et al.   DEVELOPMENT

Atypical PKC, regulated by Rho GTPases and Mek/Erk, phosphorylates Ezrin during eight-cell embryocompaction

(2013) Hongjie Liu et al.   DEVELOPMENTAL BIOLOGY

What is the Hippo pathway? Is the Hippo pathway conserved in Caenorhabditis elegans?

(2013) Z. Yang et al.   JOURNAL OF BIOCHEMISTRY

Mechanisms of CDC-42 activation during contact-induced cell polarization

(2013) E. Chan et al.   JOURNAL OF CELL SCIENCE

Quality control of embryo development

(2013) Anna Ajduk et al.   MOLECULAR ASPECTS OF MEDICINE

Epithelial polarity and spindle orientation: intersecting pathways

(2013) D. T. Bergstralh et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Modelling a risk classification of aneuploidy in human embryos using non-invasive morphokinetics

(2013) Alison Campbell et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms

(2013) Chuen Yan Leung et al.   Nature Communications

Asymmetric Localization of Cdx2 mRNA during the First Cell-Fate Decision in Early Mouse Development

(2013) Maria Skamagki et al.   Cell Reports

Phospholipase C-ζ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection

(2012) Karl Swann et al.   FERTILITY AND STERILITY

Investigation of gene expression profiles before and after embryonic genome activation and assessment of functional pathways at the human metaphase II oocyte and blastocyst stage

(2012) Georgia Kakourou et al.   FERTILITY AND STERILITY

Cortical dynein is critical for proper spindle positioning in human cells

(2012) Sachin Kotak et al.   JOURNAL OF CELL BIOLOGY

Cytoplasmic streaming in Drosophila oocytes varies with kinesin activity and correlates with the microtubule cytoskeleton architecture

(2012) S. Ganguly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Planar embryos have poor prognosis in terms of blastocyst formation and implantation

(2012) T. Ebner et al.   REPRODUCTIVE BIOMEDICINE ONLINE

A Tight Junction-Associated Merlin-Angiomotin Complex Mediates Merlin's Regulation of Mitogenic Signaling and Tumor Suppressive Functions

(2011) Chunling Yi et al.   CANCER CELL

PAR-4/LKB1 Mobilizes Nonmuscle Myosin through Anillin to Regulate C. elegans Embryonic Polarization and Cytokinesis

(2011) Nicolas T. Chartier et al.   CURRENT BIOLOGY

Dynamic localization of C. elegans TPR-GoLoco proteins mediates mitotic spindle orientation by extrinsic signaling

(2011) A. D. Werts et al.   DEVELOPMENT

Waves of early transcriptional activation and pluripotency program initiation during human preimplantation development

(2011) R. Vassena et al.   DEVELOPMENT

Elaborating polarity: PAR proteins and the cytoskeleton

(2011) J. Nance et al.   DEVELOPMENT

Human embryonic development after blastomere removal: a time-lapse analysis

(2011) Kirstine Kirkegaard et al.   HUMAN REPRODUCTION

The Transcriptome of a Human Polar Body Accurately Reflects Its Sibling Oocyte

(2011) Adrian Reich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways

(2011) Jinwei Zhu et al.   MOLECULAR CELL

Combining resources to obtain a comprehensive survey of the bovine embryo transcriptome through deep sequencing and microarrays

(2011) Claude Robert et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes

(2011) Kexi Yi et al.   NATURE CELL BIOLOGY

Microtubules induce self-organization of polarized PAR domains in Caenorhabditis elegans zygotes

(2011) Fumio Motegi et al.   NATURE CELL BIOLOGY

Oct4 kinetics predict cell lineage patterning in the early mammalian embryo

(2011) Nicolas Plachta et al.   NATURE CELL BIOLOGY

Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions

(2011) S. Culurgioni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)

(2011) S. Yuzawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic changes in leptin distribution in the progression from ovum to blastocyst of the pre-implantation mouse embryo

(2011) Laura C Schulz et al.   REPRODUCTION

Rhythmic actomyosin-driven contractions induced by sperm entry predict mammalian embryo viability

(2011) Anna Ajduk et al.   Nature Communications

LGL Can Partition the Cortex of One-Cell Caenorhabditis elegans Embryos into Two Domains

(2010) Carsten Hoege et al.   CURRENT BIOLOGY

Bazooka is required for polarisation of the Drosophila anterior-posterior axis

(2010) H. Doerflinger et al.   DEVELOPMENT

The C. elegans homolog of Drosophila Lethal giant larvae functions redundantly with PAR-2 to maintain polarity in the early embryo

(2010) A. Beatty et al.   DEVELOPMENT

Hippo signaling: growth control and beyond

(2010) G. Halder et al.   DEVELOPMENT

Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E-cadherin

(2010) R. O. Stephenson et al.   DEVELOPMENT

PAR-3 mediates the initial clustering and apical localization of junction and polarity proteins during C. elegans intestinal epithelial cell polarization

(2010) A. Achilleos et al.   DEVELOPMENT

Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst

(2010) Guoji Guo et al.   DEVELOPMENTAL CELL

The NF2 Tumor Suppressor, Merlin, Regulates Epidermal Development through the Establishment of a Junctional Polarity Complex

(2010) Andrew B. Gladden et al.   DEVELOPMENTAL CELL

Rho-Kinase Directs Bazooka/Par-3 Planar Polarity during Drosophila Axis Elongation

(2010) Sérgio de Matos Simões et al.   DEVELOPMENTAL CELL

ESHRE PGD consortium data collection X: cycles from January to December 2007 with pregnancy follow-up to October 2008†

(2010) J.C. Harper et al.   HUMAN REPRODUCTION

ESHRE PGD Consortium/Embryology Special Interest Group--best practice guidelines for polar body and embryo biopsy for preimplantation genetic diagnosis/screening (PGD/PGS)

(2010) G. L. Harton et al.   HUMAN REPRODUCTION

Epigenetic Modification Affecting Expression of Cell Polarity and Cell Fate Genes to Regulate Lineage Specification in the Early Mouse Embryo

(2010) David-Emlyn Parfitt et al.   MOLECULAR BIOLOGY OF THE CELL

RNA-Seq analysis to capture the transcriptome landscape of a single cell

(2010) Fuchou Tang et al.   Nature Protocols

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

CGEF-1 and CHIN-1 Regulate CDC-42 Activity during Asymmetric Division in the Caenorhabditis elegans Embryo

(2009) Kraig T. Kumfer et al.   MOLECULAR BIOLOGY OF THE CELL

Spindle orientation during asymmetric cell division

(2009) Karsten H. Siller et al.   NATURE CELL BIOLOGY

Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo

(2009) Magdalena Zernicka-Goetz et al.   NATURE REVIEWS GENETICS

Transcriptome Profiling of Human Pre-Implantation Development

(2009) Pu Zhang et al.   PLoS One

Cellular Symmetry Breaking during Caenorhabditis elegans Development

(2009) E. Munro et al.   Cold Spring Harbor Perspectives in Biology

Polarization of Drosophila Neuroblasts During Asymmetric Division

(2009) K. E. Prehoda   Cold Spring Harbor Perspectives in Biology

Formation of the embryonic-abembryonic axis of the mouse blastocyst: relationships between orientation of early cleavage divisions and pattern of symmetric/asymmetric divisions

(2008) M. Bischoff et al.   DEVELOPMENT

Dynamic localization of LIN-5 and GPR-1/2 to cortical force generation domains during spindle positioning

(2008) Dae Hwi Park et al.   DEVELOPMENTAL BIOLOGY

Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell mass in the mouse embryo

(2008) A. Jedrusik et al.   GENES & DEVELOPMENT

Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos

(2008) H. Zhang et al.   JOURNAL OF CELL SCIENCE

Polarization of the C. elegans Embryo by RhoGAP-Mediated Exclusion of PAR-6 from Cell Contacts

(2008) D. C. Anderson et al.   SCIENCE

Lgl and its phosphorylation by aPKC regulate oocyte polarity formation in Drosophila

(2007) A.-G. Tian et al.   DEVELOPMENT

Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos

(2007) Noriyuki Nishioka et al.   MECHANISMS OF DEVELOPMENT