A novel histone deacetylase 6-selective inhibitor suppresses synovial inflammation and joint destruction in a collagen antibody-induced arthritis mouse model

Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects

(2013) Santosh Vishwakarma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Development and therapeutic impact of HDAC6-selective inhibitors

(2012) Sabrina Dallavalle et al.   BIOCHEMICAL PHARMACOLOGY

Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma

(2012) L. Santo et al.   BLOOD

Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay

(2011) Aleksander M Grabiec et al.   ANNALS OF THE RHEUMATIC DISEASES

Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin

(2011) David Kaluza et al.   EMBO JOURNAL

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(2011) Leo Joosten et al.   MOLECULAR MEDICINE

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(2011) Charles Dinarello et al.   MOLECULAR MEDICINE

Clinical value of blocking IL-6 receptor

(2010) Toru Mima et al.   CURRENT OPINION IN RHEUMATOLOGY

The Role of HDAC6 in Cancer

(2010) Grace I. Aldana-Masangkay et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis

(2010) Tomoko Kawabata et al.   ARTHRITIS RESEARCH & THERAPY

Expression and Function of Histone Deacetylases in Rheumatoid Arthritis Synovial Fibroblasts

(2009) M. HORIUCHI et al.   JOURNAL OF RHEUMATOLOGY

Combination Strategy Targeting the Hypoxia Inducible Factor-1  with Mammalian Target of Rapamycin and Histone Deacetylase Inhibitors

(2008) H. M.W. Verheul et al.   CLINICAL CANCER RESEARCH

Histone Deacetylase Inhibitors: New Hope for Rheumatoid Arthritis?

(2008) Q. Choo et al.   CURRENT PHARMACEUTICAL DESIGN

Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors

(2008) Sabrina Dallavalle et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model

(2008) Y. Nasu et al.   OSTEOARTHRITIS AND CARTILAGE

Role of hypoxia-inducible factor-1  in hypoxia-induced expressions of IL-8, MMP-1 and MMP-3 in rheumatoid fibroblast-like synoviocytes

(2008) J. K. Ahn et al.   RHEUMATOLOGY

HDAC6: a key regulator of cytoskeleton, cell migration and cell–cell interactions

(2008) Agustín Valenzuela-Fernández et al.   TRENDS IN CELL BIOLOGY