Journal
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
Volume 12, Issue 2, Pages 174-176Publisher
WILEY-BLACKWELL PUBLISHING, INC
DOI: 10.1111/j.1756-185X.2009.01402.x
Keywords
systemic lupus erythematous; systemic lupus erythematous (clinical aspects); type 2B insulin resistance
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In type B insulin resistance and acanthosis nigricans, the insulin resistance is due to the presence of anti-insulin receptor antibody 1. Approximately one-third of patients with these antibodies have an associated illness such as systemic lupus erythematostis (SLE) or Sjogren's syndrome. This report describes a case wherein the patient had presented with uncontrolled diabetes and required > 3000 units of human insulin to control hyperglycemia. She also had features of SLE. There was complete recovery following treatment with steroids.
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