Article
Cardiac & Cardiovascular Systems
Michael X. Jiang, Eugene H. Blackstone, Tara Karamlou, Joanna Ghobrial, Ellen K. Brinza, Michael J. Haupt, Gosta B. Pettersson, Jeevanantham Rajeswaran, William G. Williams, Elizabeth V. Saarel
Summary: This study characterized anomalous aortic origin of coronary artery (AAOCA) in a large single-center adult cohort, finding that most patients were diagnosed in the presence of cardiac symptoms, 22% of patients underwent surgical repair with no deaths occurring during a median follow-up of 2.5 years. Anomalous right coronary arteries were diagnosed at an older median age compared to anomalous left main coronary arteries.
ANNALS OF THORACIC SURGERY
(2021)
Review
Cardiac & Cardiovascular Systems
Edward Buratto, Igor E. Konstantinov
Summary: The management of patients with an anomalous aortic origin of a coronary artery (AAOCA) has been a significant challenge for cardiologists and surgeons, with ongoing debates regarding the optimal surgical approach. Expert consensus guidelines published in 2017 and subsequent literature reviews have provided valuable insights for clinicians to effectively utilize in practice.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Carlos Bonilla-Ramirez, Silvana Molossi, Shagun Sachdeva, Dana Reaves-O'Neal, Prakash Masand, Carlos M. Mery, Christopher A. Caldarone, E. Dean McKenzie, Ziyad M. Binsalamah
Summary: The study compared outcomes of patients with AAOCA who underwent TAR and patients who underwent an unroofing procedure. Results showed that patients who had TAR had similar intramural length compared to patients who had an unroofing. In some cases, TAR may be a useful surgical alternative for AAOCA.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Mauro Lo Rito, Rodrigo Maximiliano Romarowski, Antonio Rosato, Silvia Pica, Francesco Secchi, Alessandro Giamberti, Ferdinando Auricchio, Alessandro Frigiola, Michele Conti
Summary: The computational model developed in this study can simulate anomalous behavior of the coronary artery and assess coronary characteristics under increasing loading stress conditions. The model showed promising results in quantifying pathological behavior and potentially aiding in patient-specific risk stratification.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Steve Bibevski, Mark Ruzmetov, Immanuel I. Turner, Frank G. Scholl
Summary: Anomalous aortic origin of right coronary artery (AAORCA) is a congenital heart lesion that can lead to coronary ischemia and sudden death. This study analyzed patients with AAORCA managed at the center, finding that 30% underwent surgical management while 70% were monitored nonsurgically. The outcomes in the midterm were excellent with functional testing showing no evidence of ischemia in the surgical patients.
ANNALS OF THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Guoliang Yang, Xiaoyue Lai, Chunshui Liang, Weijie Fan, Wanlei Fu, Zheng Liu, Hongmei Xia
Summary: This case report describes a 24-year-old male patient with a history of oral ulcer who presented with recurrent hyperpyrexia and chest pain. Echocardiography and computed tomography revealed anomalous origin of the coronary arteries, aortic valve vegetations, and a bulge at the aortic root. The patient underwent a Bentall procedure and was discharged 15 days after surgery. This case highlights the role of multimodal cardiovascular imaging in the diagnosis of rare disorders.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Pediatrics
Zhen Zhen, Ziyan Dong, Jia Na, Xi Chen, Qirui Li, Lu Gao, Yue Yuan
Summary: We conducted a retrospective study to analyze the clinical characteristics of children with different types of anomalous aortic origin of the coronary artery (AAOCA) at different ages and discuss the factors related to myocardial ischemia. The study included 69 children diagnosed with AAOCA using CT coronary angiography, and they were classified based on AAOCA type, age, and high-risk anatomy. We compared the clinical characteristics of different AAOCA types and age groups and analyzed the correlation between manifestations and high-risk anatomy. There were no significant differences in the proportions of high-risk anatomy and clinical characteristics among children with different AAOCA types.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Review
Pediatrics
Antimo Tessitore, Thomas Caiffa, Marco Bobbo, Biancamaria D'Agata Mottolese, Egidio Barbi, Daniela Chicco
Summary: Anomalous aortic origin of a coronary artery (AAOCA), especially the interarterial course of the right or left coronary artery, can lead to myocardial ischemia in pediatric patients and is a major cause of sudden cardiac death. General pediatricians may face challenges in diagnosing this anomaly, but should pay attention to exercise-related syncope, chest pain, and dyspnea. Transthoracic echocardiogram with Doppler color flow mapping is the best method to identify AAOCA.
Article
Cardiac & Cardiovascular Systems
Julien Adjedj, Fabien Hyafil, Xavier Halna du Fretay, Patrick Dupouy, Jean-Michel Juliard, Phalla Ou, Jean-Pierre Laissy, Olivier Muller, William Wijns, Pierre Aubry
Summary: This study retrospectively evaluated the physiological and clinical impact of FFRCT analysis in patients with ANOCOR. The presence of ANOCOR was associated with a moderate hemodynamic decrease of FFRCT values and low risk of cardiovascular events after a 5-year follow-up in this middle-aged population.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Tam T. Doan, Silvana Molossi, Shagun Sachdeva, James C. Wilkinson, Robert W. Loar, Justin D. Weigand, Tobias R. Schlingmann, Dana L. Reaves-O'Neal, Amol S. Pednekar, Prakash Masand, Cory V. Noel
Summary: In pediatric patients with AAOCA, DSCMR is a safe and feasible method to assess inducible hypoperfusion and WMA, with a low incidence of major/minor events. The test can accurately stratify patients into high-risk and standard-risk categories based on the presence or absence of inducible hypoperfusion.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Sri Harsha Patlolla, Elizabeth H. Stephens, Hartzell V. Schaff, Nandan S. Anavekar, William R. Miranda, Paul R. Julsrud, Joseph A. Dearani
Summary: This study examined the outcomes of surgical unroofing in 148 patients with anomalous aortic origin of coronary arteries and reported a single institution's experience. The results showed a high success rate, low early mortality, and high long-term survival, with effective control of symptoms.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Review
Cardiac & Cardiovascular Systems
Massimo A. Padalino, Anusha Jegatheeswaran, David Blitzer, Gabriella Ricciardi, Alvise Guariento
Summary: AAOCA is the second leading cause of sudden cardiac death in otherwise healthy young individuals. Surgical repair carries a certain risk but is generally effective in the short or medium term. There are various repair techniques, but the indications and limitations of each technique are often not well understood.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Pediatrics
Anusha Jegatheeswaran, Julie A. Brothers
Summary: The review focused on the anatomy, risk, evaluation, and management of anomalous aortic origin of a coronary artery (AAOCA). Management decisions should be individualized based on patient anatomy and risk factors.
CURRENT OPINION IN PEDIATRICS
(2021)
Article
Medicine, General & Internal
Hiyam Mahmoud, Eliza Cinteza, Cristiana Voicu, Irina Margarint, Iulian Rotaru, Amelia Aria, Tammam Youssef, Alin Nicolescu
Summary: Anomalous origin of the right coronary artery from the pulmonary artery is an extremely rare congenital heart disease. Although patients can be asymptomatic, early corrective intervention is generally recommended.
Article
Veterinary Sciences
Kazuki Takamura, Ayaka Chen, Shin Ono, Masami Uechi
Summary: This case report discusses a Kaninchen Dachshund diagnosed with functional mitral valve regurgitation and anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA). Evaluation using echocardiography and coronary computed tomographic angiography confirmed the presence of ALCAPA and other related abnormalities. Surgical treatment failed to ligate the anomalous artery, and the dog died from pulmonary edema 5 months after surgery.
BMC VETERINARY RESEARCH
(2022)
Article
Cardiac & Cardiovascular Systems
Soh Hosoba, Toshiaki Ito, Makoto Mori, Riku Kato, Koh Kajiyama, Shogo Maeda, Yuji Nakai, Yoshihiro Morishita
Summary: This study describes the approach and perioperative outcomes of totally endoscopic isolated and concomitant surgical aortic valve replacement (AVR) using various valve types. The results demonstrate that endoscopic AVR can safely address concomitant valve diseases.
ANNALS OF THORACIC SURGERY
(2024)