Antitumor effects of interleukin-6 (IL-6)/interleukin-6 receptor (IL-6R) signaling pathway inhibition in clear cell carcinoma of the ovary

Coexistent ARID1A–PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling

(2015) Ronald L. Chandler et al.   Nature Communications

A Phase I/II, Multiple-Dose, Dose-Escalation Study of Siltuximab, an Anti-Interleukin-6 Monoclonal Antibody, in Patients with Advanced Solid Tumors

(2014) E. Angevin et al.   CLINICAL CANCER RESEARCH

Expression and prognostic significance of the polymeric immunoglobulin receptor in epithelial ovarian cancer

(2014) Jonna Berntsson et al.   Journal of Ovarian Research

New perspectives on molecular targeted therapy in ovarian clear cell carcinoma

(2013) D S P Tan et al.   BRITISH JOURNAL OF CANCER

Minocycline Suppresses Interleukine-6, Its Receptor System and Signaling Pathways and Impairs Migration, Invasion and Adhesion Capacity of Ovarian Cancer Cells: In Vitro and In Vivo Studies

(2013) Parvin Ataie-Kachoie et al.   PLoS One

Interleukin-6 signaling pathway in targeted therapy for cancer

(2012) Yuqi Guo et al.   CANCER TREATMENT REVIEWS

Interleukin-6/interleukin-6 Receptor Pathway as a New Therapy Target in Epithelial Ovarian Cancer

(2012) Eveline M. Dijkgraaf et al.   CURRENT PHARMACEUTICAL DESIGN

Interleukin-6 signaling regulates anchorage-independent growth, proliferation, adhesion and invasion in human ovarian cancer cells

(2012) Yue Wang et al.   CYTOKINE

Clear cell carcinoma of the ovary: A review of the literature

(2012) Marcela G. del Carmen et al.   GYNECOLOGIC ONCOLOGY

IL6-STAT3-HIF Signaling and Therapeutic Response to the Angiogenesis Inhibitor Sunitinib in Ovarian Clear Cell Cancer

(2011) M. S. Anglesio et al.   CLINICAL CANCER RESEARCH

Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer

(2011) Jermaine Coward et al.   CLINICAL CANCER RESEARCH

Clear cell carcinoma of the ovary: A report from the first Ovarian Clear Cell Symposium, June 24th, 2010

(2011) Michael S. Anglesio et al.   GYNECOLOGIC ONCOLOGY

Prognosis of ovarian clear cell carcinoma compared to other histological subtypes: A meta-analysis

(2011) Yoo-Young Lee et al.   GYNECOLOGIC ONCOLOGY

Expression of soluble interleukin-6 receptor in malignant ovarian tissue

(2010) Kellie S. Rath et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Autocrine production of interleukin-6 confers cisplatin and paclitaxel resistance in ovarian cancer cells

(2010) Yue Wang et al.   CANCER LETTERS

Effects of Siltuximab on the IL-6-Induced Signaling Pathway in Ovarian Cancer

(2010) Y. Guo et al.   CLINICAL CANCER RESEARCH

Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes

(2010) K Yamaguchi et al.   ONCOGENE

Humanized Anti-Interleukin-6 Receptor Antibody Suppresses Tumor Angiogenesis and In vivo Growth of Human Oral Squamous Cell Carcinoma

(2009) S. Shinriki et al.   CLINICAL CANCER RESEARCH

Antitumor effect of humanized anti–interleukin-6 receptor antibody (tocilizumab) on glioma cell proliferation

(2009) Mareina Kudo et al.   JOURNAL OF NEUROSURGERY

siRNA and Innate Immunity

(2009) Marjorie Robbins et al.   OLIGONUCLEOTIDES

Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial–mesenchymal transition in ovarian carcinomas

(2008) M Colomiere et al.   BRITISH JOURNAL OF CANCER

Mechanisms of chemoresistance and poor prognosis in ovarian clear cell carcinoma

(2008) Hiroaki Itamochi et al.   CANCER SCIENCE