Lentiviral vector-mediated insertional mutagenesis screen identifies genes that influence androgen independent prostate cancer progression and predict clinical outcome

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome

(2015) Hyejin Cho et al.   METHODS

CCAAT/Enhancer binding protein β controls androgen-deprivation-induced senescence in prostate cancer cells

(2015) D J Barakat et al.   ONCOGENE

Interactions between Filamin A and MMP-9 Regulate Proliferation and Invasion in Renal Cell Carcinoma

(2014) Guo-Gui Sun et al.   Asian Pacific Journal of Cancer Prevention

Interaction of TIF-90 and filamin A in the regulation of rRNA synthesis in leukemic cells

(2014) L. X. T. Nguyen et al.   BLOOD

Colorectal cancer risk and patients’ survival: influence of polymorphisms in genes somatically mutated in colorectal tumors

(2014) Stefanie Huhn et al.   CANCER CAUSES & CONTROL

Conversion of Androgen Receptor Signaling From a Growth Suppressor in Normal Prostate Epithelial Cells to an Oncogene in Prostate Cancer Cells Involves a Gain of Function in c-Myc Regulation

(2014) Donald J. Vander Griend et al.   International Journal of Biological Sciences

Filamin A expression correlates with proliferation and invasive properties of human metastatic melanoma tumors: implications for survival in patients

(2014) Kai Zhang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

A novel approach to identify driver genes involved in androgen-independent prostate cancer

(2014) Ellyn N Schinke et al.   Molecular Cancer

WHSC1 Promotes Oncogenesis through Regulation of NIMA-Related Kinase-7 in Squamous Cell Carcinoma of the Head and Neck

(2014) Vassiliki Saloura et al.   MOLECULAR CANCER RESEARCH

Lentiviral Vector-based Insertional Mutagenesis Identifies Genes Involved in the Resistance to Targeted Anticancer Therapies

(2014) Marco Ranzani et al.   MOLECULAR THERAPY

Copy number alteration burden predicts prostate cancer relapse

(2014) H. Hieronymus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Filamin A regulates MMP-9 expression and suppresses prostate cancer cell migration and invasion

(2014) G. G. Sun et al.   TUMOR BIOLOGY

Histone demethylase KDM2A promotes tumor cell growth and migration in gastric cancer

(2014) Yufeng Huang et al.   TUMOR BIOLOGY

PEAR: a fast and accurate Illumina Paired-End reAd mergeR

(2013) J. Zhang et al.   BIOINFORMATICS

Comparative RNA-seq analysis reveals potential mechanisms mediating the conversion to androgen independence in an LNCaP progression cell model

(2013) Yongqing Wang et al.   CANCER LETTERS

Lung tumor-associated dendritic cell-derived resistin promoted cancer progression by increasing Wolf–Hirschhorn syndrome candidate 1/Twist pathway

(2013) Chih-Hsin Kuo et al.   CARCINOGENESIS

Punctuated Evolution of Prostate Cancer Genomes

(2013) Sylvan C. Baca et al.   CELL

Automatic cell cloning assay for determining the clonogenic capacity of cancer and cancer stem-like cells

(2013) Radek Fedr et al.   CYTOMETRY PART A

Current Status of Biomarkers for Prostate Cancer

(2013) Vicki Velonas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A novel mechanism of keratin cytoskeleton organization through casein kinase I  and FAM83H in colorectal cancer

(2013) T. Kuga et al.   JOURNAL OF CELL SCIENCE

KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling

(2013) Klaus W. Wagner et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer Gene Discovery: Exploiting Insertional Mutagenesis

(2013) Marco Ranzani et al.   MOLECULAR CANCER RESEARCH

Lentiviral vector–based insertional mutagenesis identifies genes associated with liver cancer

(2013) Marco Ranzani et al.   NATURE METHODS

Androgen Deprivation-Induced Senescence Promotes Outgrowth of Androgen-Refractory Prostate Cancer Cells

(2013) Dominick G. A. Burton et al.   PLoS One

SurvExpress: An Online Biomarker Validation Tool and Database for Cancer Gene Expression Data Using Survival Analysis

(2013) Raul Aguirre-Gamboa et al.   PLoS One

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

An antiproliferative gene FLNA regulates migration and invasion of gastric carcinoma cell in vitro and its clinical significance

(2013) G. G. Sun et al.   TUMOR BIOLOGY

Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma

(2012) Moe Matsuo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization

(2012) Benjamin A Mooso et al.   ENDOCRINE-RELATED CANCER

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

(2012) Christopher E Barbieri et al.   NATURE GENETICS

Increased expression of NuSAP in recurrent prostate cancer is mediated by E2F1

(2012) Z G Gulzar et al.   ONCOGENE

The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial–mesenchymal transition and invasive properties of prostate cancer

(2012) T Ezponda et al.   ONCOGENE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

The changing landscape in the treatment of metastatic castration-resistant prostate cancer

(2012) Joelle El-Amm et al.   Therapeutic Advances in Medical Oncology

Prostate Epithelial Pten/TP53 Loss Leads to Transformation of Multipotential Progenitors and Epithelial to Mesenchymal Transition

(2011) Philip Martin et al.   AMERICAN JOURNAL OF PATHOLOGY

KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state

(2011) David Frescas et al.   CELL CYCLE

ARFGAP3, an androgen target gene, promotes prostate cancer cell proliferation and migration

(2011) Daisuke Obinata et al.   INTERNATIONAL JOURNAL OF CANCER

Androgen-Induced Cell Migration: Role of Androgen Receptor/Filamin A Association

(2011) Gabriella Castoria et al.   PLoS One

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

MHF1-MHF2, a Histone-Fold-Containing Protein Complex, Participates in the Fanconi Anemia Pathway via FANCM

(2010) Thiyam Ramsing Singh et al.   MOLECULAR CELL

A Histone-Fold Complex and FANCM Form a Conserved DNA-Remodeling Complex to Maintain Genome Stability

(2010) Zhijiang Yan et al.   MOLECULAR CELL

Characterization of the Small RNA Transcriptomes of Androgen Dependent and Independent Prostate Cancer Cell Line by Deep Sequencing

(2010) Gang Xu et al.   PLoS One

Identification of the Transcription Factor Single-Minded Homologue 2 as a Potential Biomarker and Immunotherapy Target in Prostate Cancer

(2009) M. S. Arredouani et al.   CLINICAL CANCER RESEARCH

Molecular cell biology of androgen receptor signalling

(2009) Nigel C. Bennett et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Prostate cancer regulatory networks

(2009) Dario C. Altieri et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Tumor Immunobiological Differences in Prostate Cancer between African-American and European-American Men

(2008) T. A. Wallace et al.   CANCER RESEARCH

Clinical significance of p53 alterations in surgically treated prostate cancers

(2008) Thorsten Schlomm et al.   MODERN PATHOLOGY

Regulation of Prostate-Specific Antigen Expression by the Junctional Adhesion Molecule A

(2008) Qiuwei Wang et al.   UROLOGY