Structure-function analysis of USP1: insights into the role of Ser313 phosphorylation site and the effect of cancer-associated mutations on autocleavage

A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses

(2014) Qin Liang et al.   Nature Chemical Biology

CAPNS1 Regulates USP1 Stability and Maintenance of Genome Integrity

(2013) F. Cataldo et al.   MOLECULAR AND CELLULAR BIOLOGY

USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy

(2013) Iraia García-Santisteban et al.   Molecular Cancer

Small-Molecule Inhibitors of USP1 Target ID1 Degradation in Leukemic Cells

(2013) H. Mistry et al.   MOLECULAR CANCER THERAPEUTICS

Targeting protein–protein interactions as an anticancer strategy

(2013) Andrei A. Ivanov et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Serine Phosphorylation Is Critical for the Activation of Ubiquitin-Specific Protease 1 and Its Interaction with WD40-Repeat Protein UAF1

(2012) Mark A. Villamil et al.   BIOCHEMISTRY

A Noncanonical Cysteine Protease USP1 Is Activated through Active Site Modulation by USP1-Associated Factor 1

(2012) Mark A. Villamil et al.   BIOCHEMISTRY

Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions

(2012) Sylvie Urbé et al.   MOLECULAR BIOLOGY OF THE CELL

The Auto-Generated Fragment of the Usp1 Deubiquitylase Is a Physiological Substrate of the N-End Rule Pathway

(2012) Konstantin I. Piatkov et al.   MOLECULAR CELL

Two Nuclear Localization Signals in USP1 Mediate Nuclear Import of the USP1/UAF1 Complex

(2012) Iraia Garcia-Santisteban et al.   PLoS One

Integrative Proteomics and Tissue Microarray Profiling Indicate the Association between Overexpressed Serum Proteins and Non-Small Cell Lung Cancer

(2012) Yansheng Liu et al.   PLoS One

USP1 Deubiquitinates ID Proteins to Preserve a Mesenchymal Stem Cell Program in Osteosarcoma

(2011) Samuel A. Williams et al.   CELL

Insights into phosphorylation-dependent mechanisms regulating USP1 protein stability during the cell cycle

(2011) Xiomaris M. Cotto Rios et al.   CELL CYCLE

Selective and Cell-Active Inhibitors of the USP1/ UAF1 Deubiquitinase Complex Reverse Cisplatin Resistance in Non-small Cell Lung Cancer Cells

(2011) Junjun Chen et al.   CHEMISTRY & BIOLOGY

The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types

(2011) Alex C. Faesen et al.   CHEMISTRY & BIOLOGY

Dynamic regulation of PCNA ubiquitylation/deubiquitylation

(2011) Jennifer T. Fox et al.   FEBS LETTERS

Regulation of the Fanconi anemia pathway by a SUMO-like delivery network

(2011) K. Yang et al.   GENES & DEVELOPMENT

Human ELG1 Regulates the Level of Ubiquitinated Proliferating Cell Nuclear Antigen (PCNA) through Its Interactions with PCNA and USP1

(2010) Kyoo-young Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

Dissection of USP catalytic domains reveals five common insertion points

(2009) Yu Ye et al.   Molecular BioSystems

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

UAF1 Is a Subunit of Multiple Deubiquitinating Enzyme Complexes

(2008) Martin A. Cohn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY