Targeting STAT3/miR-21 axis inhibits epithelial-mesenchymal transition via regulating CDK5 in head and neck squamous cell carcinoma

Proton pump inhibitor pantoprazole abrogates adriamycin-resistant gastric cancer cell invasiveness via suppression of Akt/GSK-β/β-catenin signaling and epithelial–mesenchymal transition

(2015) Bin Zhang et al.   CANCER LETTERS

AC1MMYR2 impairs high dose paclitaxel-induced tumor metastasis by targeting miR-21/CDK5 axis

(2015) Yu Ren et al.   CANCER LETTERS

MicroRNA-21, up-regulated by arsenite, directs the epithelial–mesenchymal transition and enhances the invasive potential of transformed human bronchial epithelial cells by targeting PDCD4

(2015) Fei Luo et al.   TOXICOLOGY LETTERS

Loss of VHL expression contributes to epithelial–mesenchymal transition in oral squamous cell carcinoma

(2014) Shu Zhang et al.   ORAL ONCOLOGY

WP1066 Sensitizes Oral Squamous Cell Carcinoma Cells to Cisplatin by Targeting STAT3/miR-21 axis

(2014) Xuan Zhou et al.   Scientific Reports

The Role of Cdk5 in Neuroendocrine Thyroid Cancer

(2013) Karine Pozo et al.   CANCER CELL

MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways

(2013) Longlong Bao et al.   CANCER LETTERS

AC1MMYR2, an Inhibitor of Dicer-Mediated Biogenesis of Oncomir miR-21, Reverses Epithelial-Mesenchymal Transition and Suppresses Tumor Growth and Progression

(2013) Z. Shi et al.   CANCER RESEARCH

Cdk5 regulates Rap1 activity

(2013) Elias Utreras et al.   NEUROCHEMISTRY INTERNATIONAL

Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

(2013) Fei Luo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Achaete-scute homologue-1 (ASH1) stimulates migration of lung cancer cells through Cdk5/p35 pathway

(2012) Abeba Demelash et al.   MOLECULAR BIOLOGY OF THE CELL

Epithelial to mesenchymal transition (EMT) biomarkers – E-cadherin, beta-catenin, APC and Vimentin – in oral squamous cell carcinogenesis and transformation

(2012) S.Y. Chaw et al.   ORAL ONCOLOGY

Epithelial to mesenchymal transition in head and neck squamous cell carcinoma

(2012) Ashley Smith et al.   ORAL ONCOLOGY

Antagonism of miR-21 Reverses Epithelial-Mesenchymal Transition and Cancer Stem Cell Phenotype through AKT/ERK1/2 Inactivation by Targeting PTEN

(2012) Mingli Han et al.   PLoS One

Cyclin-Dependent Kinase 5 Promotes Pancreatic  -Cell Survival via Fak-Akt Signaling Pathways

(2011) M. Daval et al.   DIABETES

TGF-β-induced miR-21 negatively regulates the antiproliferative activity but has no effect on EMT of TGF-β in HaCaT cells

(2011) Tao Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Altered expression of miR-21, miR-125b, and miR-203 indicates a role for these microRNAs in oral lichen planus

(2011) K. Danielsson et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells

(2011) Mingli Han et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

 -catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness

(2011) E. Sanchez-Tillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM

(2010) Stephen B. Edge et al.   ANNALS OF SURGICAL ONCOLOGY

Inhibiting the Cyclin-Dependent Kinase CDK5 Blocks Pancreatic Cancer Formation and Progression through the Suppression of Ras-Ral Signaling

(2010) Georg Feldmann et al.   CANCER RESEARCH

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Cyclin-dependent Kinase 5 Regulates Endothelial Cell Migration and Angiogenesis

(2010) Johanna Liebl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

(2010) Xuan Zhou et al.   LABORATORY INVESTIGATION

Up-regulation of miR-21 by HER2/neuSignaling Promotes Cell Invasion

(2009) Tzu-Hsuan Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

(2008) G. Gabriely et al.   MOLECULAR AND CELLULAR BIOLOGY